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Periodic Limb Movements during Sleep: Review of Physiology and Pathology

Brian Koo
대한수면연구학회 (Korean Sleep Research Society)|2012.12|Journal of sleep medicine|제9권 제2호|pp. 23-27

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참고문헌

키워드

수면하지불안증후군주기적 팔다리 운동

초록

Periodic limb movements during sleep (PLMS) are spontaneously occurring movements of the legs which occur repetitively throughout the sleeping period. The clinical significance of these movements is unclear but when they occur frequently, sleep fragmentation can result. PLMS occur commonly in persons with the restless legs syndrome and also in the elderly even without sleep complaints. PLMS are not specific and can occur in the setting of several different diseases, including essential hypertension, stroke and sleep apnea. In this review, we cover briefly the epidemiology of PLMS and then go more into depth concerning physiology and then adverse effects associated with PLMS.

Abstract

Periodic limb movements during sleep (PLMS) are spontaneously occurring movements of the legs which occur repetitively throughout the sleeping period. The clinical significance of these movements is unclear but when they occur frequently, sleep fragmentation can result. PLMS occur commonly in persons with the restless legs syndrome and also in the elderly even without sleep complaints. PLMS are not specific and can occur in the setting of several different diseases, including essential hypertension, stroke and sleep apnea. In this review, we cover briefly the epidemiology of PLMS and then go more into depth concerning physiology and then adverse effects associated with PLMS.

참고문헌 (60)

  1. Wechsler LR, "Periodic leg movements of sleep (nocturnal myoclonus): an electrophysiological study", Ann Neurol, 19, pp.168~173 (1986)
  2. Pollmächer T, "Periodic leg movements (PLM): their relationship to sleep stages", Sleep, 16, pp.572~577 (1993)
  3. Symonds CP, "Nocturnal myoclonus", J Neurol Neurosurg Psychiatry, 16, pp.166~171 (1953)
  4. Lugaresi E, "Some periodic phenomena arising during drowsiness and sleep in man", Electroencephalogr Clin Neurophysiol, 32, pp.701~705 (1972)
  5. Bliwise D, "Periodic leg movements during sleep in the elderly", Arch Gerontol Geriatr, 4, pp.273~281 (1985)
  6. Warnes H, "Periodic limb movements and sleep apnoea", J Sleep Res, 2, pp.38~44 (1993)
  7. Kang SY, "Unilateral periodic limb movement in sleep after supratentorial cerebral infarction", Parkinsonism Relat Disord, 10, pp.429~431 (2004)
  8. Espinar-Sierra J, "Periodic leg movements in sleep in essential hypertension", Psychiatry Clin Neurosci, 51, pp.103~107 (1997)
  9. Abetz L, "Evaluating the quality of life of patients with restless legs syndrome", Clin Ther, 26, pp.925~935 (2004)
  10. Hornyak M, "Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment", Sleep Med Rev, 10, pp.169~177 (2006)
  11. American Academy of Sleep Medicine, "International classification of sleep disorders, revised: Diagnostic and coding manual", American Academy of Sleep Medicine, ~ (2001)
  12. Coleman RM, "Sleeping and waking disorders: indications and techniques", pp.265~295 (1982), AddisonWesley
  13. "Recording and scoring leg movements. The Atlas Task Force", Sleep, 16, pp.748~759 (1993)
  14. Zucconi M, "The official World Association of Sleep Medicine (WASM) standards for recording and scoring periodic leg movements in sleep (PLMS) and wakefulness (PLMW) developed in collaboration with a task force from the International Restless Legs Syndrome Study Group (IRLSSG)", Sleep Med, 7, pp.175~183 (2006)
  15. Kales A, "Measurements of all-night sleep in normal elderly persons: effects of aging", J Am Geriatr Soc, 15, pp.405~414 (1967)
  16. Bixler EO, "Nocturnal myoclonus and nocturnal myoclonic activity in the normal population", Res Commun Chem Pathol Pharmacol, 36, pp.129~140 (1982)
  17. Scofield H, "Periodic limb movements during sleep: population prevalence, clinical correlates, and racial differences", Sleep, 31, pp.1221~1227 (2008)
  18. Ancoli-Israel S, "Periodic limb movements in sleep in community-dwelling elderly", Sleep, 14, pp.496~500 (1991)
  19. Claman DM, "Prevalence and correlates of periodic limb movements in older women", J Clin Sleep Med, 2, pp.438~445 (2006)
  20. Montplaisir J, "Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: a study of 133 patients diagnosed with new standard criteria", Mov Disord, 12, pp.61~65 (1997)
  21. Ferri R, "Age-related changes in periodic leg movements during sleep in patients with restless legs syndrome", Sleep Med, 9, pp.790~798 (2008)
  22. Garcia-Borreguero D, "Correlation between rating scales and sleep laboratory measurements in restless legs syndrome", Sleep Med, 5, pp.561~565 (2004)
  23. Hornyak M, "Relationship of the restless legs syndrome rating scale scores to objective and subjective measures of sleep", Sleep, 27, pp.A309~ (2004)
  24. Baker TL, "Comparative polysomnographic study of narcolepsy and idiopathic central nervous system hypersomnia", Sleep, 9(1 Pt 2), pp.232~242 (1986)
  25. Baran AS, "Change in periodic limb movement index during treatment of obstructive sleep apnea with continuous positive airway pressure", Sleep, 26, pp.717~720 (2003)
  26. Fantini ML, "Periodic leg movements in REM sleep behavior disorder and related autonomic and EEG activation", Neurology, 59, pp.1889~1894 (2002)
  27. Hanly PJ, "Periodic limb movements during sleep in patients with congestive heart failure", Chest, 109, pp.1497~1502 (1996)
  28. Benz RL, "Potential novel predictors of mortality in end-stage renal disease patients with sleep disorders", Am J Kidney Dis, 35, pp.1052~1060 (2000)
  29. Myers BA, "Nocturnal cataclysms with myoclonus: a new side effect of clomipramine", Am J Psychiatry, 143, pp.1490~1491 (1986)
  30. Garvey MJ, "Occurrence of myoclonus in patients treated with cyclic antidepressants", Arch Gen Psychiatry, 44, pp.269~272 (1987)
  31. Dorsey CM, "Fluoxetine-induced sleep disturbance in depressed patients", Neuropsychopharmacology, 14, pp.437~442 (1996)
  32. Salín-Pascual RJ, "Sleep changes after 4 consecutive days of venlafaxine administration in normal volunteers", J Clin Psychiatry, 58, pp.348~350 (1997)
  33. Yang C, "Antidepressants and periodic leg movements of sleep", Biol Psychiatry, 58, pp.510~514 (2005)
  34. Trenkwalder C, "Electrophysiological pattern of involuntary limb movements in the restless legs syndrome", Muscle Nerve, 19, pp.155~162 (1996)
  35. de Weerd AW, "Activity patterns of leg muscles in periodic limb movement disorder", J Neurol Neurosurg Psychiatry, 75, pp.317~319 (2004)
  36. Plazzi G, "Motor pattern of periodic limb movements in sleep in idiopathic RLS patients", Sleep Med, 3, pp.S31~S34 (2002)
  37. Bara-Jimenez W, "Periodic limb movements in sleep: state-dependent excitability of the spinal flexor reflex", Neurology, 54, pp.1609~1616 (2000)
  38. Ferrillo F, "Changes in cerebral and autonomic activity heralding periodic limb movements in sleep", Sleep Med, pp.407~412 (2004)
  39. Parrino L, "The cyclic alternating pattern plays a gate-control on periodic limb movements during non-rapid eye movement sleep", J Clin Neurophysiol, 13, pp.314~323 (1996)
  40. Winkelman JW, "The evoked heart rate response to periodic leg movements of sleep", Sleep, 22, pp.575~580 (1999)
  41. Guggisberg AG, "The significance of the sympathetic nervous system in the pathophysiology of periodic leg movements in sleep", Sleep, 30, pp.755~766 (2007)
  42. Sforza E, "Cardiovascular variability during periodic leg movements: a spectral analysis approach", Clin Neurophysiol, 116, pp.1096~1104 (2005)
  43. Pennestri MH, "Nocturnal blood pressure changes in patients with restless legs syndrome", Neurology, 68, pp.1213~1218 (2007)
  44. Siddiqui F, "Rise of blood pressure with periodic limb movements in sleep and wakefulness", Clin Neurophysiol, 118, pp.1923~1930 (2007)
  45. Winkelman JW, "Prevalence and correlates of restless legs syndrome symptoms in the Wisconsin Sleep Cohort", Sleep Med, 7, pp.545~552 (2006)
  46. Winkelman JW, "Association of restless legs syndrome and cardiovascular disease in the Sleep Heart Health Study", Neurology, 70, pp.35~42 (2008)
  47. Koo BB, "Association of incident cardiovascular disease with periodic limb movements during sleep in older men: outcomes of sleep disorders in older men (MrOS) study", Circulation, 124, pp.1223~1231 (2011)
  48. Trenkwalder C, "Recent advances in the diagnosis, genetics and treatment of restless legs syndrome", J Neurol, 256, pp.539~553 (2009)
  49. Winkelmann J, "Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions", Nat Genet, 39, pp.1000~1006 (2007)
  50. Kemlink D, "Replication of restless legs syndrome loci in three European populations", J Med Genet, 46, pp.315~318 (2009)
  51. Yang Q, "Family-based and population-based association studies validate PTPRD as a risk factor for restless legs syndrome", Mov Disord, 26, pp.516~519 (2011)
  52. Schormair B, "PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome", Nat Genet, 40, pp.946~948 (2008)
  53. Stefansson H, "A genetic risk factor for periodic limb movements in sleep", N Engl J Med, 357, pp.639~647 (2007)
  54. Winkelmann J, "Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1", PLoS Genet, 7, pp.e1002171~ (2011)
  55. Karadeniz D, "Are periodic leg movements during sleep (PLMS) responsible for sleep disruption in insomnia patients?", Eur J Neurol, 7, pp.331~336 (2000)
  56. Manconi M, "Dissociation of periodic leg movements from arousals in restless legs syndrome", Ann Neurol, 71, pp.834~844 (2012)
  57. Saletu M, "Sleep laboratory studies in periodic limb movement disorder (PLMD) patients as compared with normals and acute effects of ropinirole", Hum Psychopharmacol, 16, pp.177~187 (2001)
  58. Ferri R, "Acute dopamine-agonist treatment in restless legs syndrome: effects on sleep architecture and NREM sleep instability", Sleep, 33, pp.793~800 (2010)
  59. Grewal M, "Treatment of periodic limb movements in sleep with selegiline HCl", Mov Disord, 17, pp.398~401 (2002)
  60. Manconi M, "Pramipexole versus ropinirole: polysomnographic acute effects in restless legs syndrome", Mov Disord, 26, pp.892~895 (2011)

관련 논문AI추천

Periodic Limb Movements in Sleep is Associated with Increased Mortality송지수, 이유진, 정도언, 최재원대한신경정신의학회 · PSYCHIATRY INVESTIGATION2017 · 제14권 제5호Cardiac Activation Associated with Non-Periodic Leg Movements in Comparison to Periodic Leg Movements during Sleep in Patients with Restless Legs Syndrome and Healthy Subjects전진선, 정기영, Kwang Su Cha, Min-Jong Kim, Tae-Joon Kim대한수면연구학회 · Journal of sleep medicine2018 · 제15권 제2호수면 중 주기성 사지운동의 원인 및 병태생리서민철대한수면의학회 · 수면정신생리2023 · 제30권 제2호Spontaneous Low-Frequency Cerebral Hemodynamics Oscillations in Restless Legs Syndrome with Periodic Limb Movements During Sleep: A Near-Infrared Spectroscopy Study김법민, 김충기, 변정익, 이관택, 정기영대한신경과학회 · Journal of Clinical Neurology2016 · 제12권 제1호하지불안증후군/주기적 사지운동병과 수면다원검사김광기대한수면연구학회 · Journal of sleep medicine2008 · 제5권 제2호Altered Cerebral Perfusion of Motor Cortex in Patients with Periodic Limb Movement Disorder김정식, 주은연, 홍승봉대한수면연구학회 · Journal of sleep medicine2011 · 제8권 제2호

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