분화갑상선암 환자에서 치료적 측경부림프절절제술의 적절한 범위
Optimal Surgical Extent of Therapeutic Lateral Neck Dissection in Well-Differentiated Thyroid Carcinoma Patients with Clinical Lateral Lymph Node Metastasis
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Regional neck metastases in well-differentiated thyroid carcinoma (WDTC) are relatively frequent. The prognosticeffects of lymph node (LN) metastases remain controversial. However, it is well known that lateral LN metastasisis related to the recurrence of the disease. In general, when lateral neck LN metastasis is confirmed in WDTCpatients, therapeutic lateral neck dissection is recommended. However, the optimal surgical extent of therapeuticlateral neck dissection in WDTC patients with clinical lateral LN metastasis is not clearly presented. Traditionalcomprehensive neck dissection including level II, III, IV and V even in patients with minimal lateral neck metastasesmay not be reasonable when considering both oncologic safety and functional aspects. There is controversywhether it is always necessary to perform level II and V LN dissection for all WDTC patients with clinical lateralLN metastasis. This is due to the fact that the likelihood of postoperative complications by the damage of thespinal accessory nerve increases with level II and level V dissection. Therefore, many studies have been reportedon the possibility of omitting levels II (especially IIb) and V during therapeutic comprehensive lateral neck dissection. However, there have been no definite conclusions about it, and it is still debate. In this article, we reviewed tofind out optimal lateral neck dissection range for WDTC patients with clinical lateral neck metastasis.
Abstract
Regional neck metastases in well-differentiated thyroid carcinoma (WDTC) are relatively frequent. The prognosticeffects of lymph node (LN) metastases remain controversial. However, it is well known that lateral LN metastasisis related to the recurrence of the disease. In general, when lateral neck LN metastasis is confirmed in WDTCpatients, therapeutic lateral neck dissection is recommended. However, the optimal surgical extent of therapeuticlateral neck dissection in WDTC patients with clinical lateral LN metastasis is not clearly presented. Traditionalcomprehensive neck dissection including level II, III, IV and V even in patients with minimal lateral neck metastasesmay not be reasonable when considering both oncologic safety and functional aspects. There is controversywhether it is always necessary to perform level II and V LN dissection for all WDTC patients with clinical lateralLN metastasis. This is due to the fact that the likelihood of postoperative complications by the damage of thespinal accessory nerve increases with level II and level V dissection. Therefore, many studies have been reportedon the possibility of omitting levels II (especially IIb) and V during therapeutic comprehensive lateral neck dissection. However, there have been no definite conclusions about it, and it is still debate. In this article, we reviewed tofind out optimal lateral neck dissection range for WDTC patients with clinical lateral neck metastasis.
참고문헌 (29)
- Mulla MG, "Lateral cervical lymph node metastases in papillary thyroid cancer: a systematic review of imaging-guided and prophylactic removal of the lateral compartment", Clin Endocrinol (Oxf), 77(1), pp.126~131 (2012)
- Randolph GW, "The prognostic significance of nodal metastases from papillary thyroid carcinoma can be stratified based on the size and number of metastatic lymph nodes, as well as the presence of extranodal extension", Thyroid, 22(11), pp.1144~1152 (2012)
- Qubain SW, "Distribution of lymph node micrometastasis in pN0 welldifferentiated thyroid carcinoma", Surgery, 131(3), pp.249~256 (2002)
- Ito Y, "Prognosis of patients with papillary thyroid carcinoma having clinically apparent metastasis to the lateral compartment", Endocr J, 56(6), pp.759~766 (2009)
- Haugen BR, "2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer : the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer", Thyroid, 26(1), pp.1~133 (2016)
- Nixon IJ, "The impact of nodal status on outcome in older patients with papillary thyroid cancer", Surgery, 156(1), pp.137~146 (2014)
- Kim SK, "Patterns, predictive factors and prognostic impact of multilevel metastasis in N1b papillary thyroid carcinoma", Br J Surg, 104(7), pp.857~867 (2017)
- Heaton CM, "Prognostic implications of lymph node yield in central and lateral neck dissections for well-differentiated papillary thyroid carcinoma", Thyroid, 26(3), pp.434~440 (2016)
- Joo JY, "Recurrence in regional lymph nodes after total thyroidectomy and neck dissection in patients with papillary thyroid cancer", Oral Oncol, 51(2), pp.164~169 (2015)
- Terrell JE, "Pain, quality of life, and spinal accessory nerve status after neck dissection", Laryngoscope, 110(4), pp.620~626 (2000)
- Inoue H, "Quality of life after neck dissection", Arch Otolaryngol Head Neck Surg, 132(6), pp.662~666 (2006)
- Lee BJ, "Level IIb lymph node metastasis in neck dissection for papillary thyroid carcinoma", Arch Otolaryngol Head Neck Surg, 133(10), pp.1028~1030 (2007)
- Lee J, "Is level IIb lymph node dissection always necessary in N1b papillary thyroid carcinoma patients?", World J Surg, 32(5), pp.716~721 (2008)
- Koo BS, "Predictive factors of level IIb lymph node metastasis in patients with papillary thyroid carcinoma", Ann Surg Oncol, 16(5), pp.1344~1347 (2009)
- Kupferman ME, "Predictors of level V metastasis in well-differentiated thyroid cancer", Head Neck, 30(11), pp.1469~1474 (2008)
- Kupferman ME, "Patterns of lateral neck metastasis in papillary thyroid carcinoma", Arch Otolaryngol Head Neck Surg, 130(7), pp.857~860 (2004)
- Eskander A, "Pattern of spread to the lateral neck in metastatic well-differentiated thyroid cancer : a systematic review and meta-analysis", Thyroid, 23(5), pp.583~592 (2013)
- Lombardi D, "Therapeutic lateral neck dissection in well-differentiated thyroid cancer : analysis on factors predicting distribution of positive nodes and prognosis", Head Neck, 40(2), pp.242~250 (2018)
- Kim SK, "Should level V be routinely dissected in N1b papillary thyroid carcinoma?", Thyroid, 27(2), pp.253~260 (2017)
- Won HR, "Optimal extent of lateral neck dissection for well-differentiated thyroid carcinoma with metastatic lateral neck lymph nodes : a systematic review and meta-analysis", Oral Oncol, 87, pp.117~125 (2018)
- Roh JL, "Lateral cervical lymph node metastases from papillary thyroid carcinoma : pattern of nodal metastases and optimal strategy for neck dissection", Ann Surg Oncol, 15(4), pp.1177~1182 (2008)
- King JM, "Management of lateral cervical metastases in papillary thyroid cancer : patterns of lymph node distribution", Ear Nose Throat J, 90(8), pp.386~389 (2011)
- Farrag T, "Is routine dissection of level II-B and V-A necessary in patients with papillary thyroid cancer undergoing lateral neck dissection for FNA-confirmed metastases in other levels", World J Surg, 33(8), pp.1680~1683 (2009)
- McNamara WF, "Pattern of neck recurrence after lateral neck dissection for cervical metastases in papillary thyroid cancer", Surgery, 159(6), pp.1565~1571 (2016)
- Turanli S, "Is the type of dissection in lateral neck metastasis for differentiated thyroid carcinoma important?", Otolaryngol Head Neck Surg, 136(6), pp.957~960 (2007)
- Strajina V, "Comprehensive lateral neck dissection in papillary thyroid carcinoma may reduce lateral neck recurrence rates", Ann Surg Oncol, 26(1), pp.86~92 (2019)
- Javid M, "Dissection of levels II through V is required for optimal outcomes in patients with lateral neck lymph node metastasis from papillary thyroid carcinoma", J Am Coll Surg, 222(6), pp.1066~1073 (2016)
- Zhang D, "Comparison between video-assisted and open lateral neck dissection for papillary thyroid carcinoma with lateral neck lymph node metastasis : a prospective randomized study", J Laparoendosc Adv Surg Tech A, 27(11), pp.1151~1157 (2017)
- Kupferman ME, "Safety of modified radical neck dissection for differentiated thyroid carcinoma", Laryngoscope, 114(3), pp.403~406 (2004)