렘수면행동장애에서 수면 중 신체손상병력과 수면무호흡과의 연관성
The Association between History of Body Injury during Sleep and Obstructive Sleep Apnea in REM Sleep Behavior Disorder
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objectives: To investigate whether a history of body injury is associated with obstructive sleep apnea (OSA) in patients with rapid eye movement (REM) sleep behavior disorder (RBD). Methods: We enrolled 56 consecutive patients with RBD, a history of dream-enacting behaviors, and polysomnographic evidence of REM sleep without atonia. Participants were asked whether they had any history of body injuries such as self-injury or bed-partner injury during sleep. The demographic characteristics and polysomnographic parameters of the groups with a history of injury (n=34, 60.7%) and without (n=22, 39.3%) were compared. The association between the history of injury and OSA was assessed. Results: OSA [apnea-hypopnea index (AHI) ≥5/h) was associated with a history of body injury [odds ratio (OR)=6.25, 95% confidence interval (CI)= 1.64–23.84]. Additionally, the logistic regression analysis showed that insomnia severity index (OR=0.87, 95% CI=0.80–0.98) and AHI (OR=1.10, 95% CI=1.02–1.18) were associated with history of body injury. Conclusions: Therefore, we can conclude that history of body injury is related to obstructive sleep apnea in patients with RBD.
Abstract
Objectives: To investigate whether a history of body injury is associated with obstructive sleep apnea (OSA) in patients with rapid eye movement (REM) sleep behavior disorder (RBD). Methods: We enrolled 56 consecutive patients with RBD, a history of dream-enacting behaviors, and polysomnographic evidence of REM sleep without atonia. Participants were asked whether they had any history of body injuries such as self-injury or bed-partner injury during sleep. The demographic characteristics and polysomnographic parameters of the groups with a history of injury (n=34, 60.7%) and without (n=22, 39.3%) were compared. The association between the history of injury and OSA was assessed. Results: OSA [apnea-hypopnea index (AHI) ≥5/h) was associated with a history of body injury [odds ratio (OR)=6.25, 95% confidence interval (CI)= 1.64–23.84]. Additionally, the logistic regression analysis showed that insomnia severity index (OR=0.87, 95% CI=0.80–0.98) and AHI (OR=1.10, 95% CI=1.02–1.18) were associated with history of body injury. Conclusions: Therefore, we can conclude that history of body injury is related to obstructive sleep apnea in patients with RBD.
참고문헌 (23)
- Schenck CH, "Chronic behavioral disorders of human REM sleep : a new category of parasomnia", Sleep, 9, pp.293~308 (1986)[DOI]
- Schenck CH, "Rapid eye movement sleep behavior disorder. A treatable parasomnia affecting older adults", JAMA, 257, pp.1786~1789 (1987)[DOI]
- Iranzo A, "Rapid-eye-movement sleep behaviour disorder as an early marker for a neurodegenerative disorder: a descriptive study", Lancet Neurol, 5, pp.572~577 (2006)[DOI]
- Schenck CH, "REM sleep behavior disorder : clinical, developmental, and neuroscience perspectives 16 years after its formal identification in SLEEP", Sleep, 25, pp.120~138 (2002)[DOI]
- American Academy of Sleep Medicine, "International classification of sleep disorders: diagnostic and coding manual. 3rd ed", American Academy of Sleep Medicine, ~ (2014)
- Shahar E, "Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study", Am J Respir Crit Care Med, 163, pp.19~25 (2001)[DOI]
- Gabryelska A, "Prevalence of obstructive sleep apnoea in REM behaviour disorder : response to continuous positive airway pressure therapy", Sleep Breath, 22, pp.825~830 (2018)[DOI]
- Olson EJ, "Rapid eye movement sleep behaviour disorder : demographic, clinical and laboratory findings in 93 cases", Brain, 123, pp.331~339 (2000)[DOI]
- Iranzo A, "Severe obstructive sleep apnea", hypopnea mimicking REM sleep behavior disorder, 2005, pp.28, 203~206
- Johns MW, "A new method for measuring daytime sleepiness : the Epworth sleepiness scale", Sleep, 14, pp.540~545 (1991)[DOI]
- Beck AT, "An inventory for measuring depression", Arch Gen Psychiatry, 4, pp.561~571 (1961)[DOI]
- Bastien CH, "Validation of the Insomnia Severity Index as an outcome measure for insomnia research", Sleep Med, 2, pp.297~307 (2001)[DOI]
- Iber C, "The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications" (2007), American Academy of Sleep Medicine
- Arnulf I, "REM sleep behavior disorder : motor manifestations and pathophysiology", Mov Disord, 27, pp.677~689 (2012)[DOI]
- BaHammam AS, "Dreams and nightmares in patients with obstructive sleep apnea : a review", Front Neurol, 10, pp.1127~ (2019)[DOI]
- Pagel JF, "The nightmares of sleep apnea : nightmare frequency declines with increasing apnea hypopnea index", J Clin Sleep Med, 6, pp.69~73 (2010)[DOI]
- Hackius M, "Electrophysiological evidence for alternative motor networks in REM sleep behavior disorder", J Neurosci, 36, pp.11795~11800 (2016)[DOI]
- Tahmasian M, "Structural and functional neural adaptations in obstructive sleep apnea : an activation likelihood estimation meta-analysis", Neurosci Biobehav Rev, 65, pp.142~156 (2016)[DOI]
- Schuld A, "Obstructive sleep apnea syndrome induced by clonazepam in a narcoleptic patient with REM-sleep-behavior disorder", J Sleep Res, 8, pp.321~322 (1999)[DOI]
- Bugalho P, "The influence of sleep disordered breathing in REM sleep behavior disorder", Sleep Med, 37, pp.210~215 (2017)[DOI]
- Kim KT, "Quality of life in patients with an idiopathic rapid eye movement sleep behaviour disorder in Korea", J Sleep Res, 26, pp.422~427 (2017)[DOI]
- 성민재, "렘수면행동장애 환자의 꿈 회상 빈도와 수면의 질", Journal of sleep medicine, 14(2), pp.55~60 (2017), 대한수면연구학회[DOI]
- Wu MN, "More severe hypoxemia is associated with better subjective sleep quality in obstructive sleep apnea", BMC Pulm Med, 15, pp.117~ (2015)[DOI]