성별에 따른 수면장애의 원인 질환 분석
Sex Differences in Etiologies of Sleep Disorders
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초록
Objectives: To investigate the etiologies of sleep disorders according to sex. Methods: We enrolled 1,270 patients who complained of insomnia (n=328) or sleep apnea (n=942) for more than 6 months and classified them into primary insomnia (PI, n=120), comorbid obstructive sleep apnea with insomnia (COMISA, n=146), and obstructive sleep apnea (OSA, n=884) groups based on their polysomnography (PSG) findings, demographics, sleep-related symptoms, and questionnaire results (Insomnia Severity Index and Epworth Sleepiness Scale). Results: The highest prevalence of females was observed in PI (71.7%), and the lowest in the OSA group (15.6%). Males were more prevalent than females in the COMISA group (58.2% vs. 41.8%). Regarding the etiology of insomnia, half of the male patients with complaints of insomnia had OSA, while only one-third of the females had OSA. Thirteen percent of female who complained of OSA-related symptoms were diagnosed as normal. There were few differences in PSG data between female and male patients in the PI and COMISA groups. Females with OSA showed longer total sleep time than males with OSA in PSG. The self-reported questionnaire responses of patients in the COMISA and PI groups were similar, and PSG data of patients in the COMISA and OSA groups were comparable regardless of sex. Conclusions: Females and males have different sleep perceptions and sleep-related complaints. Thus,
Abstract
Objectives: To investigate the etiologies of sleep disorders according to sex. Methods: We enrolled 1,270 patients who complained of insomnia (n=328) or sleep apnea (n=942) for more than 6 months and classified them into primary insomnia (PI, n=120), comorbid obstructive sleep apnea with insomnia (COMISA, n=146), and obstructive sleep apnea (OSA, n=884) groups based on their polysomnography (PSG) findings, demographics, sleep-related symptoms, and questionnaire results (Insomnia Severity Index and Epworth Sleepiness Scale). Results: The highest prevalence of females was observed in PI (71.7%), and the lowest in the OSA group (15.6%). Males were more prevalent than females in the COMISA group (58.2% vs. 41.8%). Regarding the etiology of insomnia, half of the male patients with complaints of insomnia had OSA, while only one-third of the females had OSA. Thirteen percent of female who complained of OSA-related symptoms were diagnosed as normal. There were few differences in PSG data between female and male patients in the PI and COMISA groups. Females with OSA showed longer total sleep time than males with OSA in PSG. The self-reported questionnaire responses of patients in the COMISA and PI groups were similar, and PSG data of patients in the COMISA and OSA groups were comparable regardless of sex. Conclusions: Females and males have different sleep perceptions and sleep-related complaints. Thus,
참고문헌 (33)
- American Academy of Sleep Medicine, "International Classification of Sleep Disorders-Third Edition (ICSD-3)", American Academy of Sleep Medicine, ~ (2014)
- Morin CM, "Chronic insomnia", Lancet, 379, pp.1129~1141 (2012)[DOI]
- Zhang B, "Sex differences in insomnia : a meta-analysis", Sleep, 29, pp.85~93 (2006)[DOI]
- Kim KW, "Prevalence and clinical characteristics of insomnia and its subtypes in the Korean elderly", Arch Gerontol Geriatr, 68, pp.68~75 (2017)[DOI]
- Marin JM, "Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure : an observational study", Lancet, 365, pp.1046~1053 (2005)[DOI]
- Choi SJ, "Sleep misperception in chronic insomnia patients with obstructive sleep apnea syndrome: implications for clinical assessment", J Clin Sleep Med, 12, pp.1517~1525 (2016)[DOI]
- Luyster FS, "Comorbid insomnia and obstructive sleep apnea : challenges for clinical practice and research", J Clin Sleep Med, 6, pp.196~204 (2010)[DOI]
- Heinzer R, "Impact of sex and menopausal status on the prevalence, clinical presentation, and comorbidities of sleep-disordered breathing", Sleep Med, 51, pp.29~36 (2018)[DOI]
- Pyun So Young, "Gender Differences in Korean Patients with Obstructive Sleep Apnea", sleep medicine research, 11(2), pp.121~128 (2020), 대한수면학회[DOI]
- Voderholzer U, "Are there gender differences in objective and subjective sleep measures? A study of insomniacs and healthy controls", Depress Anxiety, 17, pp.162~172 (2003)[DOI]
- Loução-de-Amorim I, "Men and women with chronic insomnia disorder and OSAS : different responses to CPAP", Sleep Sci, 12, pp.190~195 (2019)[DOI]
- 조용원, "Validation of a Korean Version of the Insomnia Severity Index", Journal of Clinical Neurology, 10(3), pp.210~215 (2014), 대한신경과학회[DOI]
- Cho YW, "The reliability and validity of the Korean version of the Epworth sleepiness scale", Sleep Breath, 15, pp.377~384 (2011)[DOI]
- Berry RB, "AASM scoring manual updates for 2017 (version 2.4)", J Clin Sleep Med, 13, pp.665~666 (2017)[DOI]
- 강미리, "수면다원검사로 검증된 만성 불면증의 동반 수면질환 분석", 대한신경과학회지, 36(1), pp.1~8 (2018), 대한신경과학회[DOI]
- 성민재, "렘수면행동장애 환자의 꿈 회상 빈도와 수면의 질", Journal of sleep medicine, 14(2), pp.55~60 (2017), 대한수면연구학회[DOI]
- Morgenthaler TI, "Practice parameters for the clinical evaluation and treatment of circadian rhythm sleep disorders. An American Academy of Sleep Medicine report", Sleep, 30, pp.1445~1459 (2007)[DOI]
- Zhang Y, "Worldwide and regional prevalence rates of co-occurrence of insomnia and insomnia symptoms with obstructive sleep apnea : a systematic review and meta-analysis", Sleep Med Rev, 45, pp.1~17 (2019)[DOI]
- Sweetman A, "Co-morbid insomnia and sleep apnea(COMISA) : prevalence, consequences, methodological considerations, and recent randomized controlled trials", Brain Sci, 9, pp.371~ (2019)[DOI]
- Janssen HCJP, "Management of insomnia in sleep disordered breathing", Eur Respir Rev, 28, pp.190080~ (2019)[DOI]
- Glidewell RN, "Predictors and patterns of insomnia symptoms in OSA before and after PAP therapy", Sleep Med, 15, pp.899~905 (2014)[DOI]
- van de Laar M, "The role of personality traits in insomnia", Sleep Med Rev, 14, pp.61~68 (2010)[DOI]
- Weisberg YJ, "Gender differences in personality across the ten aspects of the big five", Front Psychol, 2, pp.178~ (2011)[DOI]
- Fernandez-Mendoza J, "Sleep misperception and chronic insomnia in the general population : role of objective sleep duration and psychological profiles", Psychosom Med, 73, pp.88~97 (2011)[DOI]
- Green MJ, "Social class and gender patterning of insomnia symptoms and psychiatric distress : a 20-year prospective cohort study", BMC Psychiatry, 14, pp.152~ (2014)[DOI]
- Pillar G, "Airway mechanics and ventilation in response to resistive loading during sleep : influence of gender", Am J Respir Crit Care Med, 162, pp.1627~1632 (2000)[DOI]
- Sidani S, "Gender differences in perpetuating factors, experience and management of chronic insomnia", J Gend Stud, 28, pp.402~413 (2019)[DOI]
- Duffy JF, "Sex difference in the near-24-hour intrinsic period of the human circadian timing system", Proc Natl Acad Sci U S A, 108(Suppl 3), pp.15602~15608 (2011)[DOI]
- Van Reen E, "Sex of college students moderates associations among bedtime, time in bed, and circadian phase angle", J Biol Rhythms, 28, pp.425~431 (2013)[DOI]
- Obayashi K, "Lower melatonin secretion in older females : gender differences independent of light exposure profiles", J Epidemiol, 25, pp.38~43 (2015)[DOI]
- Levenson JC, "The pathophysiology of insomnia", Chest, 147, pp.1179~1192 (2015)[DOI]
- Sweetman A, "Cognitive and behavioral therapy for insomnia increases the use of continuous positive airway pressure therapy in obstructive sleep apnea participants with comorbid insomnia : a randomized clinical trial", Sleep, 42, pp.zsz178~ (2019)[DOI]
- Brock MS, "Comorbid insomnia and sleep apnea: a prevalent but overlooked disorder", Sleep Breath, 22, pp.1~3 (2018)[DOI]