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대한갑상선학회 갑상선분화암 진료권고안; Part III. 진행성 갑상선분화암의 치료 - 제3장 진행성 갑상선분화암 환자의 방사성요오드 치료 2024

Korean Thyroid Association Guidelines on the Management of Differentiated Thyroid Cancers; Part III. Management of Advanced Differentiated Thyroid Cancers - Chapter 3. Radioactive Iodine Therapy in Advanced Thyroid Cancer 2024

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참고문헌

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초록

Radioactive iodine (RAI) therapy can effectively eliminate persistent or recurrent disease in patients with advanced differentiated thyroid cancer (DTC), potentially improving progression-free, disease-specific, and overall survival rates. Repeated administration of RAI along with thyroid-stimulating hormone (TSH) suppression is the mainstay of treatment for patients with distant metastases. Remarkably, one in three patients with distant metastases can be cured using RAI therapy and experience a near-normal life expectancy. Patients with elevated serum thyroglobulin and a negative post-RAI scan may be considered for empiric RAI therapy in the absence of structurally evident disease. However, in some patients, the iodine uptake capacity of advanced lesions decreases over time, potentially resulting in RAI-refractory disease. RAI-administered dose can be either empirically fixed high activities or dosimetry-based individualized activities for treatment of known diseases. The preparation method (levothyroxine withdrawal vs. recombinant human TSH administration) should be individualized for each patient. RAI therapy is a reasonable and safe treatment for patients with advanced DTC. Despite the risk of radiation exposure, administration of low-activity RAI has not been associated with an increased risk of a secondary primary cancer (SPM), leukemia, infertility, adverse pregnancy outcomes, etc. However, depending on the cumulative dose, there is a risk of acute or delayed-onset adverse effects including salivary gland damage, dental caries, nasolacrimal duct obstruction, and SPM. Therefore, as with any treatment, the expected benefit must justify the use of RAI in patients with advanced DTC.

Abstract

Radioactive iodine (RAI) therapy can effectively eliminate persistent or recurrent disease in patients with advanced differentiated thyroid cancer (DTC), potentially improving progression-free, disease-specific, and overall survival rates. Repeated administration of RAI along with thyroid-stimulating hormone (TSH) suppression is the mainstay of treatment for patients with distant metastases. Remarkably, one in three patients with distant metastases can be cured using RAI therapy and experience a near-normal life expectancy. Patients with elevated serum thyroglobulin and a negative post-RAI scan may be considered for empiric RAI therapy in the absence of structurally evident disease. However, in some patients, the iodine uptake capacity of advanced lesions decreases over time, potentially resulting in RAI-refractory disease. RAI-administered dose can be either empirically fixed high activities or dosimetry-based individualized activities for treatment of known diseases. The preparation method (levothyroxine withdrawal vs. recombinant human TSH administration) should be individualized for each patient. RAI therapy is a reasonable and safe treatment for patients with advanced DTC. Despite the risk of radiation exposure, administration of low-activity RAI has not been associated with an increased risk of a secondary primary cancer (SPM), leukemia, infertility, adverse pregnancy outcomes, etc. However, depending on the cumulative dose, there is a risk of acute or delayed-onset adverse effects including salivary gland damage, dental caries, nasolacrimal duct obstruction, and SPM. Therefore, as with any treatment, the expected benefit must justify the use of RAI in patients with advanced DTC.

참고문헌 (126)

  1. Avram AM, "SNMMI procedure standard", EANM practice guideline for nuclear medicine evaluation and therapy of differentiated thyroid cancer : abbreviated version, 2022, pp.63(6), 15N~35N
  2. Filetti S, "Thyroid cancer : ESMO clinical practice guidelines for diagnosis, treatment and follow-up", Ann Oncol, 30(12), pp.1856~1883 (2019)
  3. Schmidt A, "Radioactive iodine-refractory differentiated thyroid cancer : an uncommon but challenging situation", Arch Endocrinol Metab, 61(1), pp.81~89 (2017)
  4. Haymart MR, "Disease severity and radioactive iodine use for thyroid cancer", J Clin Endocrinol Metab, 98(2), pp.678~686 (2013)
  5. Van Nostrand D, "The benefits and risks of I-131 therapy in patients with well-differentiated thyroid cancer", Thyroid, 19(12), pp.1381~1391 (2009)
  6. Avenia N, "Locally advanced thyroid cancer : therapeutic options", Chir Ital, 56(4), pp.501~508 (2004)
  7. Osorio M, "Systematic review of site distribution of bone metastases in differentiated thyroid cancer", Head Neck, 39(4), pp.812~818 (2017)
  8. Ruegemer JJ, "Distant metastases in differentiated thyroid carcinoma : a multivariate analysis of prognostic variables", J Clin Endocrinol Metab, 67(3), pp.501~508 (1988)
  9. Diessl S, "Impact of moderate vs stringent TSH suppression on survival in advanced differentiated thyroid carcinoma", Clin Endocrinol(Oxf), 76(4), pp.586~592 (2012)
  10. Durante C, "Long-term outcome of 444 patients with distant metastases from papillary and follicular thyroid carcinoma : benefits and limits of radioiodine therapy", J Clin Endocrinol Metab, 91(8), pp.2892~2899 (2006)
  11. Ronga G, "Lung metastases from differentiated thyroid carcinoma. A 40 years' experience", Q J Nucl Med Mol Imaging, 48(1), pp.12~19 (2004)
  12. Ilgan S, "Iodine-131 treatment and high-resolution CT : results in patients with lung metastases from differentiated thyroid carcinoma", Eur J Nucl Med Mol Imaging, 31(6), pp.825~830 (2004)
  13. Hod N, "Differentiated thyroid carcinoma in children and young adults : evaluation of response to treatment", Clin Nucl Med, 30(6), pp.387~390 (2005)
  14. Schlumberger M, "Radioactive iodine treatment and external radiotherapy for lung and bone metastases from thyroid carcinoma", J Nucl Med, 37(4), pp.598~605 (1996)
  15. Bernier MO, "Survival and therapeutic modalities in patients with bone metastases of differentiated thyroid carcinomas", J Clin Endocrinol Metab, 86(4), pp.1568~1573 (2001)
  16. Kato S, "Current management of bone metastases from differentiated thyroid cancer", Cancers(Basel), 13(17), pp.4429~ (2021)
  17. Wexler JA, "Approach to the thyroid cancer patient with bone metastases", J Clin Endocrinol Metab, 96(8), pp.2296~2307 (2011)
  18. Van Nostrand D, "Radioiodine in the treatment of thyroid cancer", Endocrinol Metab Clin North Am, 36(3), pp.807~822 (2007)
  19. Schlumberger M, "Defects in iodide metabolism in thyroid cancer and implications for the follow-up and treatment of patients", Nat Clin Pract Endocrinol Metab, 3(3), pp.260~269 (2007)
  20. Van Nostrand D, "Dosimetrically determined doses of radioiodine for the treatment of metastatic thyroid carcinoma", Thyroid, 12(2), pp.121~134 (2002)
  21. Chiesa C, "Individualized dosimetry in the management of metastatic differentiated thyroid cancer", Q J Nucl Med Mol Imaging, 53(5), pp.546~561 (2009)
  22. Maxon HR, "Relation between effective radiation dose and outcome of radioiodine therapy for thyroid cancer", N Engl J Med, 309(16), pp.937~941 (1983)
  23. Thomas SR, "In vivo quantitation of lesion radioactivity using external counting methods", Med Phys, 03(04), pp.253~255 (1976)
  24. Holst JP, "Radioiodine therapy for thyroid cancer and hyperthyroidism in patients with end-stage renal disease on hemodialysis", Thyroid, 15(12), pp.1321~1331 (2005)
  25. Driedger AA, "A pragmatic protocol for I-131 rhTSHstimulated ablation therapy in patients with renal failure", Clin Nucl Med, 31(8), pp.454~457 (2006)
  26. Jarzab B, "Juvenile differentiated thyroid carcinoma and the role of radioiodine in its treatment : a qualitative review", Endocr Relat Cancer, 12(4), pp.773~803 (2005)
  27. Verburg FA, "I-131 activities as high as safely administrable(AHASA)for the treatment of children and adolescents with advanced differentiated thyroid cancer", J Clin Endocrinol Metab, 96(8), pp.E1268~E1271 (2011)
  28. Ma C, "Recombinant human thyrotropin(rhTSH)aided radioiodine treatment for residual or metastatic differentiated thyroid cancer", Cochrane Database Syst Rev, 2010(11), pp.CD008302~ (2010)
  29. Sgouros G, "Patient-specific dosimetry for 131I thyroid cancer therapy using 124I PET and 3-dimensional-internal dosimetry(3D-ID)software", J Nucl Med, 45(8), pp.1366~1372 (2004)
  30. Jentzen W, "Optimized 124I PET dosimetry protocol for radioiodine therapy of differentiated thyroid cancer", J Nucl Med, 49(6), pp.1017~1023 (2008)
  31. Pettinato C, "Usefulness of 124I PET", CT imaging to predict absorbed doses in patients affected by metastatic thyroid cancer and treated with 131I, 2012, pp.56(6), 509~514
  32. Haugen BR, "2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer : the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer", Thyroid, 26(1), pp.1~133 (2016)
  33. Kulkarni K, "The relative frequency in which empiric dosages of radioiodine would potentially overtreat or undertreat patients who have metastatic well-differentiated thyroid cancer", Thyroid, 16(10), pp.1019~1023 (2006)
  34. Tuttle RM, "Empiric radioactive iodine dosing regimens frequently exceed maximum tolerated activity levels in elderly patients with thyroid cancer", J Nucl Med, 47(10), pp.1587~1591 (2006)
  35. Hugo J, "Recombinant human thyroid stimulating hormone-assisted radioactive iodine remnant ablation in thyroid cancer patients at intermediate to high risk of recurrence", Thyroid, 22(10), pp.1007~1015 (2012)
  36. Gomes-Lima CJ, "Metastatic differentiated thyroid cancer survival is unaffected by mode of preparation for(131)I administration", J Endocr Soc, 6(5), pp.bvac032~ (2022)
  37. Simoes-Pereira J, "Outcomes of thyrotropin alfa versus levothyroxine withdrawal-aided radioiodine therapy for distant metastasis of papillary thyroid cancer", Thyroid, 31(10), pp.1514~1522 (2021)
  38. Tala H, "Five-year survival is similar in thyroid cancer patients with distant metastases prepared for radioactive iodine therapy with either thyroid hormone withdrawal or recombinant human TSH", J Clin Endocrinol Metab, 96(7), pp.2105~2111 (2011)
  39. Tsai HC, "Feasibility of recombinant human TSH as a preparation for radioiodine therapy in patients with distant metastases from papillary thyroid cancer : comparison of long-term survival outcomes with thyroid hormone withdrawal", Diagnostics(Basel), 12(1), pp.221~ (2022)
  40. Campopiano MC, "No difference in the outcome of metastatic thyroid cancer patients when using recombinant or endogenous TSH", Eur J Endocrinol, 183(4), pp.411~417 (2020)
  41. Klubo-Gwiezdzinska J, "Radioiodine treatment of metastatic thyroid cancer : relative efficacy and side effect profile of preparation by thyroid hormone withdrawal versus recombinant human thyrotropin", Thyroid, 22(3), pp.310~317 (2012)
  42. Park S, "Comparison of recombinant human thyroid-stimulating hormone and thyroid hormone withdrawal for 131 I therapy in patients with intermediate-to high-risk thyroid cancer : a systematic review and meta-analysis", Clin Nucl Med, 49(3), pp.e96~e104 (2024)
  43. Luster M, "Use of recombinant human thyrotropin before radioiodine therapy in patients with advanced differentiated thyroid carcinoma", J Clin Endocrinol Metab, 85(10), pp.3640~3645 (2000)
  44. Rani D, "Examining recombinant human TSH primed 131I therapy protocol in patients with metastatic differentiated thyroid carcinoma : comparison with the traditional thyroid hormone withdrawal protocol", Eur J Nucl Med Mol Imaging, 41(9), pp.1767~1780 (2014)
  45. Jarzab B, "Recombinant human TSH-aided radioiodine treatment of advanced differentiated thyroid carcinoma : a single-centre study of 54 patients", Eur J Nucl Med Mol Imaging, 30(8), pp.1077~1086 (2003)
  46. Robbins RJ, "S. and Canadian Thyrogen Compassionate Use Program Investigator Group. Recombinant human thyrotropin-assisted radioiodine therapy for patients with metastatic thyroid cancer who could not elevate endogenous thyrotropin or be withdrawn from thyroxine", Thyroid, 16(11), pp.1121~1130 (2006)
  47. Fatourechi V, "Lack of impact of radioiodine therapy in tg-positive, diagnostic whole-body scan-negative patients with follicular cell-derived thyroid cancer", J Clin Endocrinol Metab, 87(4), pp.1521~1526 (2002)
  48. Koh JM, "Effects of therapeutic doses of 131I in thyroid papillary carcinoma patients with elevated thyroglobulin level and negative 131I whole-body scan : comparative study", Clin Endocrinol(Oxf), 58(4), pp.421~427 (2003)
  49. Kloos RT, "Approach to the patient with a positive serum thyroglobulin and a negative radioiodine scan after initial therapy for differentiated thyroid cancer", J Clin Endocrinol Metab, 93(5), pp.1519~1525 (2008)
  50. -fluorodeoxyglucoseavid metastatic thyroid cancer lesions to treatment with high-dose radioactive iodine, "Thyroid", 2001, 1169~1175
  51. Salvatore B, "Fluorodeoxyglucose PET", CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and(131)I ablation, 2008, pp.52(1), 2~8
  52. fluoro-2-deoxy-D-glucose-positron emission tomography scanning, "J Clin Endocrinol Metab", 2006, 498~505
  53. Yim JH, "Long-term consequence of elevated thyroglobulin in differentiated thyroid cancer", Thyroid, 23(1), pp.58~63 (2013)
  54. Miyauchi A, "Prognostic impact of serum thyroglobulin doubling-time under thyrotropin suppression in patients with papillary thyroid carcinoma who underwent total thyroidectomy", Thyroid, 21(7), pp.707~716 (2011)
  55. Black EG, "Serial serum thyroglobulin measurements in the management of differentiated thyroid carcinoma", Clin Endocrinol(Oxf), 27(1), pp.115~120 (1987)
  56. Huang SH, "Sequential follow-up of serum thyroglobulin and whole body scan in thyroid cancer patients without initial metastasis", Thyroid, 16(12), pp.1273~1278 (2006)
  57. Mazzaferri EL, "Clinical review 128 : current approaches to primary therapy for papillary and follicular thyroid cancer", J Clin Endocrinol Metab, 86(4), pp.1447~1463 (2001)
  58. Pacini F, "Outcome of differentiated thyroid cancer with detectable serum Tg and negative diagnostic(131)I whole body scan : comparison of patients treated with high(131)I activities versus untreated patients", J Clin Endocrinol Metab, 86(9), pp.4092~4097 (2001)
  59. van Tol KM, "Outcome in patients with differentiated thyroid cancer with negative diagnostic whole-body scanning and detectable stimulated thyroglobulin", Eur J Endocrinol, 148(6), pp.589~596 (2003)
  60. Kabasakal L, "Treatment of iodine-negative thyroglobulin-positive thyroid cancer : differences in outcome in patients with macrometastases and patients with micrometastases", Eur J Nucl Med Mol Imaging, 31(11), pp.1500~1504 (2004)
  61. Tramontin MY, "High thyroglobulin and negative whole-body scan : no long-term benefit of empiric radioiodine therapy", Endocrine, 73(2), pp.398~406 (2021)
  62. Yuan L, "Outcome of patients with differentiated thyroid cancer treated with empirical radioiodine therapy on the basis of thyroglobulin elevation negative iodine scintigraphy(TENIS)syndrome without structural disease : a retrospective cohort study", Ann Nucl Med, 37(1), pp.18~25 (2023)
  63. Kim K, "Efficacy of empirical 131I radioiodine therapy in well-differentiated thyroid carcinoma patients with thyroglobulin-elevated negative iodine scintigraphy syndrome: a systematic review and meta-analysis", Clin Nucl Med (2024)
  64. Teng CJ, "Use of radioactive iodine for thyroid cancer and risk of second primary malignancy : a nationwide population-based study", J Natl Cancer Inst, 108(2), pp.djv314~ (2016)
  65. Rubino C, "Second primary malignancies in thyroid cancer patients", Br J Cancer, 89(9), pp.1638~1644 (2003)
  66. Walter MA, "The dental safety profile of high-dose radioiodine therapy for thyroid cancer : long-term results of a longitudinal cohort study", J Nucl Med, 48(10), pp.1620~1625 (2007)
  67. Kloos RT, "Nasolacrimal drainage system obstruction from radioactive iodine therapy for thyroid carcinoma", J Clin Endocrinol Metab, 87(12), pp.5817~5820 (2002)
  68. Brown AP, "The risk of second primary malignancies up to three decades after the treatment of differentiated thyroid cancer", J Clin Endocrinol Metab, 93(2), pp.504~515 (2008)
  69. Sandeep TC, "Second primary cancers in thyroid cancer patients : a multinational record linkage study", J Clin Endocrinol Metab, 91(5), pp.1819~1825 (2006)
  70. Subramanian S, "Second primary malignancy risk in thyroid cancer survivors : a systematic review and meta-analysis", Thyroid, 17(12), pp.1277~1288 (2007)
  71. Delgado A, "Clinical endpoints in oncology-a primer", Am J Cancer Res, 11(4), pp.1121~1131 (2021)
  72. Nakada K, "Does lemon candy decrease salivary gland damage after radioiodine therapy for thyroid cancer?", J Nucl Med, 46(2), pp.261~266 (2005)
  73. Jentzen W, "The influence of saliva flow stimulation on the absorbed radiation dose to the salivary glands during radioiodine therapy of thyroid cancer using 124I PET", CT imaging, 2010, pp.37(12), 2298~2306
  74. Van Nostrand D, "Radiopharmacokinetics of radioiodine in the parotid glands after the administration of lemon juice", Thyroid, 20(10), pp.1113~1119 (2010)
  75. Mandel SJ, "Radioactive iodine and the salivary glands", Thyroid, 13(3), pp.265~271 (2003)
  76. Bomeli SR, "Interventional sialendoscopy for treatment of radioiodine-induced sialadenitis", Laryngoscope, 119(5), pp.864~867 (2009)
  77. Prendes BL, "Therapeutic sialendoscopy for the management of radioiodine sialadenitis", Arch Otolaryngol Head Neck Surg, 138(1), pp.15~19 (2012)
  78. Bhayani MK, "Sialendoscopy for patients with radioiodine-induced sialadenitis and xerostomia", Thyroid, 25(7), pp.834~838 (2015)
  79. Auttara-Atthakorn A, "Prevention of salivary gland dysfunction in patients treated with radioiodine for differentiated thyroid cancer : a systematic review of randomized controlled trials", Front Endocrinol(Lausanne), 13, pp.960265~ (2022)
  80. Yu CY, "A systematic review and meta-analysis of subsequent malignant neoplasm risk after radioactive iodine treatment of thyroid cancer", Thyroid, 28(12), pp.1662~1673 (2018)
  81. Reinecke MJ, "Second primary malignancies induced by radioactive iodine treatment of differentiated thyroid carcinoma-a critical review and evaluation of the existing evidence", Eur J Nucl Med Mol Imaging, 49(9), pp.3247~3256 (2022)
  82. Ko KY, "(131)I treatment for thyroid cancer and the risk of developing salivary and lacrimal gland dysfunction and a second primary malignancy : a nationwide population-based cohort study", Eur J Nucl Med Mol Imaging, 42(8), pp.1172~1178 (2015)
  83. Kim KJ, "Linear association between radioactive iodine dose and second primary malignancy risk in thyroid cancer", J Natl Cancer Inst, 115(6), pp.695~702 (2023)
  84. Hong CM, "Second primary malignancy after radioiodine therapy in thyroid cancer patient : a nationwide study", Nucl Med Mol Imaging, 57(6), pp.275~286 (2023)
  85. Hong CM, "Incidence rate and factors associated with the development of secondary cancers after radioiodine therapy in differentiated thyroid cancer : a multicenter retrospective study", Eur J Nucl Med Mol Imaging, 49(5), pp.1661~1670 (2022)
  86. Khang AR, "The risk of second primary malignancy is increased in differentiated thyroid cancer patients with a cumulative(131)I dose over 37 GBq", Clin Endocrinol(Oxf), 83(1), pp.117~123 (2015)
  87. Kim S, "Second primary malignancy risk in thyroid cancer and matched patients with and without radioiodine therapy analysis from the observational health data sciences and informatics", Eur J Nucl Med Mol Imaging, 49(10), pp.3547~3556 (2022)
  88. Seo GH, "Increased risk of leukemia after radioactive iodine therapy in patients with thyroid cancer : a nationwide, population-based study in Korea", Thyroid, 25(8), pp.927~934 (2015)
  89. Ali Hailan YM, "Chronic myeloid leukemia following exposure to radioactive iodine(I131) : a systematic review", Oncology, 101(6), pp.362~368 (2023)
  90. Chen AY, "The development of breast carcinoma in women with thyroid carcinoma", Cancer, 92(2), pp.225~231 (2001)
  91. Zhang Y, "Risk of second primary breast cancer after radioactive iodine treatment in thyroid cancer : a systematic review and meta-analysis", Nucl Med Commun, 37(2), pp.110~115 (2016)
  92. Hall P, "Cancer risks in thyroid cancer patients", Br J Cancer, 64(1), pp.159~163 (1991)
  93. Travis CC, "131I ablation treatment in young females after the Chernobyl accident", J Nucl Med, 47(10), pp.1723~1727 (2006)
  94. Pasqual E, "Association between radioactive iodine treatment for pediatric and young adulthood differentiated thyroid cancer and risk of second primary malignancies", J Clin Oncol, 40(13), pp.1439~1449 (2022)
  95. Seo GH, "Radioactive iodine treatment for children and young adults with thyroid cancer in South Korea : a population-based study", J Clin Endocrinol Metab, 106(7), pp.e2580~e2588 (2021)
  96. Benua RS, "The relation of radioiodine dosimetry to results and complications in the treatment of metastatic thyroid cancer", Am J Roentgenol Radium Ther Nucl Med, 87, pp.171~182 (1962)
  97. Perry WF, "The urinary excretion and thyroid uptake of iodine in renal disease", J Clin Invest, 31(5), pp.457~463 (1952)
  98. Smith LH, "Clinical and laboratory considerations in metabolic bone disease", Ann Clin Lab Sci, 5(4), pp.252~256 (1975)
  99. Morrish DW, "131I treatment of thyroid papillary carcinoma in a patient with renal failure", Cancer, 66(12), pp.2509~2513 (1990)
  100. Saracyn M, "Can radioiodine be administered effectively and safely to a patient with severe chronic kidney disease?", Clin Endocrinol(Oxf), 81(2), pp.169~174 (2014)
  101. Sioka C, "Effects of I-131 therapy on gonads and pregnancy outcome in patients with thyroid cancer", Fertil Steril, 95(5), pp.1552~1559 (2011)
  102. Yaish I, "A single radioactive iodine treatment has a deleterious effect on ovarian reserve in women with thyroid cancer : results of a prospective pilot study", Thyroid, 28(4), pp.522~527 (2018)
  103. Acibucu F, "Evaluation of ovarian reserve with AMH level in patients with well-differentiated thyroid cancer receiving radioactive iodine ablation treatment", Exp Clin Endocrinol Diabetes, 124(10), pp.593~596 (2016)
  104. Giusti M, "Anti-Mullerian hormone in pre-menopausal females after ablative radioiodine treatment for differentiated thyroid cancer", Endocrine, 60(3), pp.516~523 (2018)
  105. Vini L, "Prognosis for fertility and ovarian function after treatment with radioiodine for thyroid cancer", Postgrad Med J, 78(916), pp.92~93 (2002)
  106. Dottorini ME, "Assessment of female fertility and carcinogenesis after iodine-131 therapy for differentiated thyroid carcinoma", J Nucl Med, 36(1), pp.21~27 (1995)
  107. Sawka AM, "A systematic review examining the effects of therapeutic radioactive iodine on ovarian function and future pregnancy in female thyroid cancer survivors", Clin Endocrinol(Oxf), 69(3), pp.479~490 (2008)
  108. Garsi JP, "Therapeutic administration of 131I for differentiated thyroid cancer : radiation dose to ovaries and outcome of pregnancies", J Nucl Med, 49(5), pp.845~852 (2008)
  109. Lin JD, "Outcome of pregnancy after radioactive iodine treatment for well differentiated thyroid carcinomas", J Endocrinol Invest, 21(10), pp.662~667 (1998)
  110. Schlumberger M, "Exposure to radioactive iodine-131 for scintigraphy or therapy does not preclude pregnancy in thyroid cancer patients", J Nucl Med, 37(4), pp.606~612 (1996)
  111. van der Lingen ACJ, "The link between cardiac status and depression and anxiety in implantable cardioverter defibrillator patients : design and first results of the PSYCHE-ICD study", J Psychosom Res, 167, pp.111182~ (2023)
  112. Wu JX, "Reproductive outcomes and nononcologic complications after radioactive iodine ablation for well-differentiated thyroid cancer", Thyroid, 25(1), pp.133~138 (2015)
  113. Alexander EK, "2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum", Thyroid, 27(3), pp.315~389 (2017)
  114. Kahaly GJ, "2018 European Thyroid Association guideline for the management of Graves' hyperthyroidism", Eur Thyroid J, 7(4), pp.167~186 (2018)
  115. Van Nostrand D, "The utility of radioiodine scans prior to iodine 131 ablation in patients with well-differentiated thyroid cancer", Thyroid, 19(8), pp.849~855 (2009)
  116. Bartel Chair TB, "SNMMI procedure standard for scintigraphy for differentiated thyroid cancer", J Nucl Med Technol, 48(3), pp.202~209 (2020)
  117. American Thyroid Association Taskforce on Radioiodine Safety, "Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131I : practice recommendations of the American Thyroid Association", Thyroid, 21(4), pp.335~346 (2011)
  118. Bernard N, "Severe adverse effects of bromocriptine in lactation inhibition : a pharmacovigilance survey", BJOG, 122(9), pp.1244~1251 (2015)
  119. Wichers M, "Testicular function after radioiodine therapy for thyroid carcinoma", Eur J Nucl Med, 27(5), pp.503~507 (2000)
  120. Hyer S, "Testicular dose and fertility in men following I(131)therapy for thyroid cancer", Clin Endocrinol(Oxf), 56(6), pp.755~758 (2002)
  121. Cai Y, "The effect of radioactive iodine treatment for differentiated thyroid cancer on male gonadal function : a meta-analysis", Endocr Connect, 12(12), pp.e230299~ (2023)
  122. Lushbaugh CC, "The effects of gonadal irradiation in clinical radiation therapy : a review", Cancer, 37(2 Suppl), pp.1111~1125 (1976)
  123. Sarkar SD, "Subsequent fertility and birth histories of children and adolescents treated with 131I for thyroid cancer", J Nucl Med, 17(6), pp.460~464 (1976)
  124. Canale D, "Effects of radioiodine treatment for differentiated thyroid cancer on testis function", Clin Endocrinol(Oxf), 82(2), pp.295~299 (2015)
  125. Bourcigaux N, "Impact on testicular function of a single ablative activity of 3. 7 GBq radioactive iodine for differentiated thyroid carcinoma", Hum Reprod, 33(8), pp.1408~1416 (2018)
  126. Mazzaferri EL, "Gonadal damage from 131I therapy for thyroid cancer", Clin Endocrinol(Oxf), 57(3), pp.313~314 (2002)

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