다계통위축증 환자의 수면양상
Sleep Pattern of Patients with Multiple System Atrophy
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Objects : Multiple system atrophy (MSA) is a disorder that shows cerebellar dysfunction, autonomic symptoms, or long tract signs in addition to the parkinsonism. Contrary to that in the Parkinson’s disease, little is known about the sleep in this disease. Methods : Questionnaires and polysomnographic data were analyzed in 20 MSA patients as a pilot study. The analyses were compared to the values reported previously. Results : The questionnaire revealed the total sleep time (TST) of 7.5 hours and 25% of patients complained restless legs. Nightmare, snore, sleep apnea, and sleep talking were the main complaints. On the polysomnography, the mean TST was 248 minutes and the wake after sleep onset (WASO) was 145 minutes. Fifty-five percent of patients showed obstructive sleep apnea (OSA) and 90% showed snore or stridor. Periodic limb movements (PLMs) were present in 60% and REM sleep behavior disorder (RBD) was noticed in 15% of patients. Conclusion : MSA is a disorder with various sleep problems such as short TST, OSA, snore and stridor, PLMs, and RBD. If left unnoticed, the patient’s long-term health may be negatively impacted by these abnormalities.
Abstract
Objects : Multiple system atrophy (MSA) is a disorder that shows cerebellar dysfunction, autonomic symptoms, or long tract signs in addition to the parkinsonism. Contrary to that in the Parkinson’s disease, little is known about the sleep in this disease. Methods : Questionnaires and polysomnographic data were analyzed in 20 MSA patients as a pilot study. The analyses were compared to the values reported previously. Results : The questionnaire revealed the total sleep time (TST) of 7.5 hours and 25% of patients complained restless legs. Nightmare, snore, sleep apnea, and sleep talking were the main complaints. On the polysomnography, the mean TST was 248 minutes and the wake after sleep onset (WASO) was 145 minutes. Fifty-five percent of patients showed obstructive sleep apnea (OSA) and 90% showed snore or stridor. Periodic limb movements (PLMs) were present in 60% and REM sleep behavior disorder (RBD) was noticed in 15% of patients. Conclusion : MSA is a disorder with various sleep problems such as short TST, OSA, snore and stridor, PLMs, and RBD. If left unnoticed, the patient’s long-term health may be negatively impacted by these abnormalities.