갑상선암 수술 후 유착방지제(Guardix-SGⓇ) 사용과 배액량과의 관계
Anti-adhesive Agent (Guardix-SGⓇ) Does Not Influence the Drainage Volume after Thyroid Cancer Surgery
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Purpose: This study was conducted to investigate whether the use of HA-CMC solution in thyroid surgery influences drainage amount and hospital stay.Methods: Between November 2012 and December 12, 147 patients with thyroid cancer who underwent total thyroidectomy with central compartment neck dissection were analyzed retrospectively. The patients were divided into four groups; those with or without HA-CMC solution application and high or low output drainage.Results: There were no differences in hospital stay and mean total drainage between the with and without HA-CMC solution application groups (P=0.230, P=0.732). The mean hospital stay was 2.2±0.4 days for the low output of drainage group and 3.1±0.6 days for the high output drainage group (P＜0.001). There was no significant difference in the use of HA-CMC solution (41.1% vs. 56.8%, P=0.070).Conclusion: The use of HA-CMC solution in thyroid cancer surgery might not increase drainage amount and make hospital stay longer.
Abstract
Purpose: This study was conducted to investigate whether the use of HA-CMC solution in thyroid surgery influences drainage amount and hospital stay.Methods: Between November 2012 and December 12, 147 patients with thyroid cancer who underwent total thyroidectomy with central compartment neck dissection were analyzed retrospectively. The patients were divided into four groups; those with or without HA-CMC solution application and high or low output drainage.Results: There were no differences in hospital stay and mean total drainage between the with and without HA-CMC solution application groups (P=0.230, P=0.732). The mean hospital stay was 2.2±0.4 days for the low output of drainage group and 3.1±0.6 days for the high output drainage group (P＜0.001). There was no significant difference in the use of HA-CMC solution (41.1% vs. 56.8%, P=0.070).Conclusion: The use of HA-CMC solution in thyroid cancer surgery might not increase drainage amount and make hospital stay longer.
참고문헌 (23)
- Shaha AR, "TNM classification of thyroid carcinoma", World J Surg, 31, pp.879~887 (2007)
- Lee YS, "Practical management of well differentiated thyroid carcinoma in Korea", Endocr J, 55, pp.1015~1024 (2008)
- 이용상, "Postoperative Complications of Thyroid Cancer in a Single Center Experience", Journal of Korean Medical Science, 25(4), pp.541~545 (2010), 대한의학회
- Takamura Y, "Stretching exercises to reduce symptoms of postoperative neck discomfort after thyroid surgery: prospective randomized study", World J Surg, 29, pp.775~779 (2005)
- Yigit O, "Efficacy of anti-adhesive barriers in secondary thyroidectomy: an experimental study", Laryngoscope, 114, pp.1668~1673 (2004)
- Park WS, "Anti-adhesive effect and safety of sodium hyaluronate and sodium carboxymethyl cellulose solution in thyroid surgery", Asian J Surg, 33, pp.25~30 (2010)
- Park JH, "The efficacy and safety of Guardix-SG® in patients who are undergoing thyroid surgery: a randomized, prospective, double- blinded study", Korean J Endocrine Surg, 9, pp.127~132 (2009)
- Falk K, "Reduction of experimental adhesion formation by inhibition of plasminogen activator inhibitor type 1", Br J Surg, 88, pp.286~289 (2001)
- Burns JW, "Preclinical evaluation of Seprafilm bioresorbable membrane", Eur J Surg Suppl, 577, pp.40~48 (1997)
- Becker JM, "Prevention of postoperative abdominal adhesions by a sodium hyaluronate-based bioresorbable membrane: a prospective, randomized, double-blind multicenter study", J Am Coll Surg, 183, pp.297~306 (1996)
- Fazio VW, "Reduction in adhesive small-bowel obstruction by Seprafilm adhesion barrier after intestinal resection", Dis Colon Rectum, 49, pp.1~11 (2006)
- Kutlay J, "Comparative effectiveness of several agents for preventing postoperative adhesions", World J Surg, 28, pp.662~665 (2004)
- Sahin M, "The effects of anti-adhesion materials in preventing postoperative adhesion in abdominal cavity (anti-adhesion materials for postoperative adhesions)", Inflammation, 30, pp.244~249 (2007)
- Kristoffersson A, "Drainage in uncomplicated thyroid and parathyroid surgery", Br J Surg, 73, pp.121~122 (1986)
- Scerrino G, "Esophageal motility changes after thyroidectomy; possible associations with postoperative voice and swallowing disorders: preliminary results", Otolaryngol Head Neck Surg, 148, pp.926~932 (2013)
- Hellebrekers BW, "Use of fibrinolytic agents in the prevention of postoperative adhesion formation", Fertil Steril, 74, pp.203~212 (2000)
- Shaha AR, "Recurrent differentiated thyroid cancer", Endocr Pract, 18, pp.600~603 (2012)
- Clark OH, "Recurrent thyroid cancer", J Endocrinol Invest, 18, pp.167~169 (1995)
- Park SO, "Prevention of capsular contracture with Guardix-SG(Ⓡ) after silicone implant insertion", Aesthetic Plast Surg, 37, pp.543~548 (2013)
- Weber R, "20. Weber R, Keerl R, Hochapfel F, Draf W, Toffel PH. Packing in endonasal surgery", Am J Otolaryngol, 22, pp.306~320 (2001)
- Elkins TE, "Adhesion prevention by solutions of sodium carboxymethylcellulose in the rat", I. Fertil Steril, 41, pp.926~928 (1984)
- Yilmaz O, "Assessment of the efficacy of absorbable adhesion barriers on dissection in esophagus operations", Int J Pediatr Otorhinolaryngol, 71, pp.409~414 (2007)
- Ahmad G, "Barrier agents for adhesion prevention after gynaecological surgery", Cochrane Database Syst Rev, 2 (2008)