Papillary Thyroid Carcinoma with Retropharyngeal Node Metastasis Demonstrating Negative I-131 but Positive FDG Uptake on PET/CT
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Papillary thyroid carcinoma (PTC) is commonly accompanied by cervical lymph node metastasis, whereas metastases to the retropharyngeal lymph nodes (RPN) are rare. Radioactive iodine (RAI) ablation is recommended for detection and treatment of differentiated thyroid carcinoma (DTC). However, in some cases of iodine-negative DTC, F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) can aid in detection of additional lesions. We report on a patient with PTC who had retropharyngeal node involvement with iodine-negative features and low thyroglobulin level at the time of diagnosis but with metastasis identified on FDG PET/CT.
Abstract
Papillary thyroid carcinoma (PTC) is commonly accompanied by cervical lymph node metastasis, whereas metastases to the retropharyngeal lymph nodes (RPN) are rare. Radioactive iodine (RAI) ablation is recommended for detection and treatment of differentiated thyroid carcinoma (DTC). However, in some cases of iodine-negative DTC, F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) can aid in detection of additional lesions. We report on a patient with PTC who had retropharyngeal node involvement with iodine-negative features and low thyroglobulin level at the time of diagnosis but with metastasis identified on FDG PET/CT.
참고문헌 (13)
- Togashi T, "Surgical management of retropharyngeal nodes metastases from papillary thyroid carcinoma", World J Surg, 38, pp.2831~2837 (2014)
- Lee JW, "Clinical utility of 18F-FDG PET", CT concurrent with 131I therapy in intermediateto-high-risk patients with differentiated thyroid cancer: dual-center experience with 286 patients, 2013, pp.54, 1230~1236
- Mirallié E, "Therapeutic impact of 18FDG-PET", CT in the management of iodine-negative recurrence of differentiated thyroid carcinoma, 2007, pp.142, 952~958
- American Thyroid Association (ATA) Guidelines Taskforce on Thyroid Nodules and Differentiated Thyroid Cancer, "Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer", Thyroid, 19, pp.1167~1214 (2009)
- Lee J, "Is level IIb lymph node dissection always necessary in N1b papillary thyroid carcinoma patients?", World J Surg, 32, pp.716~721 (2008)
- Merdad M, "Metastatic papillary thyroid cancer with lateral neck disease: pattern of spread by level", Head Neck, 35, pp.1439~1442 (2013)
- Cheng PT, "Objective comparison of shoulder dysfunction after three neck dissection techniques", Ann Otol Rhinol Laryngol, 109, pp.761~766 (2000)
- 이초록, "분화 갑상선암에서 측경부 림프절 절제술의 범위", The Journal of Endocrine Surgery, 14(1), pp.1~6 (2014), 대한갑상선-내분비외과학회
- Leger AF, "Upper retropharyngeal node involvement in differentiated thyroid carcinoma demonstrated by 131I scintigraphy", Br J Radiol, 73, pp.1260~1264 (2000)
- Rouvière H, "Anatomy of the human lymphatic system", pp.5~65 (1938), Edwards Brothers
- Kim WG, "Change of serum antithyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma", J Clin Endocrinol Metab, 93, pp.4683~4689 (2008)
- Park EK, "Recurrent", metastatic thyroid carcinomas false negative for serum thyroglobulin but positive by posttherapy I-131 whole body scans, 2009, pp.36, 172~179
- Bachelot A, "Relationship between tumor burden and serum thyroglobulin level in patients with papillary and follicular thyroid carcinoma", Thyroid, 12, pp.707~711 (2002)