Adrenal Schwannoma: Rare Entity of Adrenal Incidentaloma
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Purpose: Adrenal schwannomas are very rare and are usually incidentally found on autopsy and imaging. The aim of this study was to describe our experience of adrenal schwannoma and review the literature regarding this rare tumor.Methods: To identify patients with adrenal schwannoma, the MEDLINE database was searched via the major electronic database PubMed using the medical subject heading terms “adrenal” and “schwannoma”. Thirty-nine adrenal schwannoma cases, including two from our institution were included.Results: The mean age at diagnosis was 47.95 years (range, 11∼89 years). The female:male ratio was 21:17. Sixteen patients had tumors on the right side, 19 on the left, while one patient had bilateral tumors. The mean tumor size was 6.12 cm (range, 0.6∼14.5 cm), and the mean tumor weight was 161.3 g (range, 31.5∼600.0 g). Sixteen tumors were solid, four cystic, one solid and cystic, and 18 were not described. Histologically, 14 cases were Antoni A, two were Antoni B, and 12 had concomitant Antoni A and B.Conclusion: Adrenal schwannoma is usually an incidental finding, and the clinician must have a high index of suspicion to recognize it when imaging reveals suggestive features.
Abstract
Purpose: Adrenal schwannomas are very rare and are usually incidentally found on autopsy and imaging. The aim of this study was to describe our experience of adrenal schwannoma and review the literature regarding this rare tumor.Methods: To identify patients with adrenal schwannoma, the MEDLINE database was searched via the major electronic database PubMed using the medical subject heading terms “adrenal” and “schwannoma”. Thirty-nine adrenal schwannoma cases, including two from our institution were included.Results: The mean age at diagnosis was 47.95 years (range, 11∼89 years). The female:male ratio was 21:17. Sixteen patients had tumors on the right side, 19 on the left, while one patient had bilateral tumors. The mean tumor size was 6.12 cm (range, 0.6∼14.5 cm), and the mean tumor weight was 161.3 g (range, 31.5∼600.0 g). Sixteen tumors were solid, four cystic, one solid and cystic, and 18 were not described. Histologically, 14 cases were Antoni A, two were Antoni B, and 12 had concomitant Antoni A and B.Conclusion: Adrenal schwannoma is usually an incidental finding, and the clinician must have a high index of suspicion to recognize it when imaging reveals suggestive features.
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