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Treatment Decision Making in Papillary Thyroid Microcarcinoma

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The objective of this article is to detail the treatment for papillary thyroid microcarcinoma (PTMC). The literature presents only few contributions, with controversial results, about comparison between ‘active surveillance’ and surgery. Hemithyroidectomy is the treatment of choice for PTMC. Thyroidectomy is indicated in cases of multifocality, extrathyroid tumor growth, and familial PTMCs. Active surveillance can only be done under well-defined and controlled conditions. Collected findings and agreements with the patient must be precisely documented, also for medico-legal reasons. An observation of PTMC seems most appropriate for patients >60 years of age. In the case of observation of a PTMC, a lifelong examination of the tumor disease must be carried out, since tumor growth or metastases can still occur after 10–15 years. The follow-up periods for the ‘active surveillance’ proposed from the literature review are too short to conclude this as a real alternative.

Abstract

The objective of this article is to detail the treatment for papillary thyroid microcarcinoma (PTMC). The literature presents only few contributions, with controversial results, about comparison between ‘active surveillance’ and surgery. Hemithyroidectomy is the treatment of choice for PTMC. Thyroidectomy is indicated in cases of multifocality, extrathyroid tumor growth, and familial PTMCs. Active surveillance can only be done under well-defined and controlled conditions. Collected findings and agreements with the patient must be precisely documented, also for medico-legal reasons. An observation of PTMC seems most appropriate for patients >60 years of age. In the case of observation of a PTMC, a lifelong examination of the tumor disease must be carried out, since tumor growth or metastases can still occur after 10–15 years. The follow-up periods for the ‘active surveillance’ proposed from the literature review are too short to conclude this as a real alternative.

참고문헌 (34)

  1. "SEER Cancer Statistics Review 1975-2014" (2017)[URL]
  2. "Krebs in Deutschland 2011/2012" (2016)[URL]
  3. Gschwandtner E, "Increase of papillary thyroid microcarcinoma and a plea for restrictive treatment: a retrospective study of 1,391 prospective documented patients", Surgery, 159, pp.503~511 (2016)[DOI]
  4. Ahn HS, "Koreas thyroid-cancer epidemic--screening and overdiagnosis", N Engl J Med, 371, pp.1765~1767 (2014)[DOI]
  5. Ito Y, "An observation trial without surgical treatment in patients with papillary microcarcinoma of the thyroid", Thyroid, 13, pp.381~387 (2003)[DOI]
  6. Kwon H, "Active surveillance for patients with papillary thyroid microcarcinoma: a single center's experience in Korea", J Clin Endocrinol Metab, 102, pp.1917~1925 (2017)[DOI]
  7. Tuttle RM, "Natural history and tumor volume kinetics of papillary thyroid cancers during active surveillance", JAMA Otolaryngol Head Neck Surg, 143, pp.1015~1020 (2017)[DOI]
  8. Lang W, "Occult carcinomas of the thyroid. Evaluation of 1,020 sequential autopsies", Am J Clin Pathol, 90, pp.72~76 (1988)[DOI]
  9. Musholt TJ, "Detection of papillary thyroid carcinoma by analysis of BRAF and RET", PTC1 mutations in fine-needle aspiration biopsies of thyroid nodules, 2010, pp.34, 2595~2603
  10. Machens A, "Impact of central node dissection on postoperative morbidity in pediatric patients with suspected or proven thyroid cancer", Surgery, 160, pp.484~492 (2016)[DOI]
  11. Ito Y, "Patient age is significantly related to the progression of papillary microcarcinoma of the thyroid under observation", Thyroid, 24, pp.27~34 (2014)[DOI]
  12. Neuhold N, "Latent carcinoma of the thyroid in Austria: a systematic autopsy study", Endocr Pathol, 12, pp.23~31 (2001)[DOI]
  13. Miyauchi A, "Insights into the management of papillary microcarcinoma of the thyroid", Thyroid, 28, pp.23~31 (2018)[DOI]
  14. Fukuoka O, "Natural history of asymptomatic papillary thyroid microcarcinoma: time-dependent changes in calcification and vascularity during active surveillance", World J Surg, 40, pp.529~537 (2016)[DOI]
  15. Miyauchi A, "Clinical trials of active surveillance of papillary microcarcinoma of the thyroid", World J Surg, 40, pp.516~522 (2016)[DOI]
  16. Haugen BR, "2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer", Thyroid, 26, pp.1~133 (2016)[DOI]
  17. Mohamad Yusof A, "Integrated characterization of microRNA and mRNA transcriptome in papillary thyroid carcinoma", Front Endocrinol (Lausanne), 9, pp.158~ (2018)[DOI]
  18. Li F, "BRAFV600E mutation in papillary thyroid microcarcinoma: a meta-analysis", Endocr Relat Cancer, 22, pp.159~168 (2015)[DOI]
  19. Perros P, "Guidelines for the management of thyroid cancer", Clin Endocrinol (Oxf), 81(Suppl 1), pp.1~122 (2014)
  20. Lamartina L, "Are evidence-based guidelines reflected in clinical practice? An analysis of prospectively collected data of the Italian Thyroid Cancer Observatory", Thyroid, 27, pp.1490~1497 (2017)[DOI]
  21. Takami H, "Revisiting the guidelines issued by the Japanese Society of Thyroid Surgeons and Japan Association of Endocrine Surgeons: a gradual move towards consensus between Japanese and western practice in the management of thyroid carcinoma", World J Surg, 38, pp.2002~2010 (2014)[DOI]
  22. Kim SK, "Total thyroidectomy versus lobectomy in conventional papillary thyroid microcarcinoma: analysis of 8,676 patients at a single institution", Surgery, 161, pp.485~492 (2017)[DOI]
  23. Hou CJ, "Diagnostic value of ultrasound features and sex of fetuses in female patients with papillary thyroid microcarcinoma", Sci Rep, 8, pp.7510~ (2018)[DOI]
  24. Jeon MJ, "Features of papillary thyroid microcarcinoma associated with lateral cervical lymph node metastasis", Clin Endocrinol (Oxf), 86, pp.845~851 (2017)[DOI]
  25. Oh HS, "Young age and male sex are predictors of large-volume central neck lymph node metastasis in clinical N0 papillary thyroid microcarcinomas", Thyroid, 27, pp.1285~1290 (2017)[DOI]
  26. Leboulleux S, "Papillary thyroid microcarcinoma: time to shift from surgery to active surveillance?", Lancet Diabetes Endocrinol, 4, pp.933~942 (2016)[DOI]
  27. Chen Y, "BRAF(V600E) is correlated with recurrence of papillary thyroid microcarcinoma: a systematic review, multi-institutional primary data analysis, and meta-analysis", Thyroid, 26, pp.248~255 (2016)[DOI]
  28. Hay ID, "Papillary thyroid microcarcinoma: a study of 900 cases observed in a 60-year period", Surgery, 144, pp.980~987 (2008)[DOI]
  29. Kim HI, "High serum TSH level is associated with progression of papillary thyroid microcarcinoma during active surveillance", J Clin Endocrinol Metab, 103, pp.446~451 (2018)
  30. Miyauchi A, "Estimation of the lifetime probability of disease progression of papillary microcarcinoma of the thyroid during active surveillance", Surgery, 163, pp.48~52 (2018)[DOI]
  31. Gao M, "2016 Chinese expert consensus and guidelines for the diagnosis and treatment of papillary thyroid microcarcinoma", Cancer Biol Med, 14, pp.203~211 (2017)[DOI]
  32. Merdad M, "Current management of papillary thyroid microcarcinoma in Canada", J Otolaryngol Head Neck Surg, 43, pp.32~ (2014)[DOI]
  33. van den Bergh RC, "Psychological aspects of active surveillance", Curr Opin Urol, 22, pp.237~242 (2012)[DOI]

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