골수흡인물 농축액 및 기질유래연골형성 수술 이후 관찰된 거골의 골연골병변의 골유합: 증례 보고
Bony Union of Osteochondral Lesion of the Talus after Bone Marrow Aspirate Concentrate and Matrix-Induced Chondrogenesis: A Case Report
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Traditionally, arthroscopic microfracture and autologous osteochondral autograft transplantation have been the primary surgical treat- ments for osteochondral lesions of the talus. On the other hand, recent advancements have introduced alternative approaches, such as autologous chondrocyte transplantation, matrix-derived autologous chondrocyte transplantation, intra-articular injection of concen- trated bone marrow aspirate concentrate, and the use of fibrin glue to address chondral defects. Furthermore, some studies have ex- plored a combination of bone marrow aspirate and matrix-derived chondrogenesis. In light of these developments, this report presents a case study of a young male patient in his early twenties with a relatively large osteochondral lesion exceeding 1.5 cm2 on the medial talar dome. Instead of removing the osteochondral lesion, a surgical approach was employed to retain the lesion while addressing the unstable cartilage in the affected area. This approach involved a combination of bone marrow aspirate concentrate and matrix-derived chondro- genesis. The treatment yielded favorable clinical outcomes and ultimately successfully induced the bony union of osteochondral lesions. This paper reports the author’s experience with this innovative approach with a review of the relevant literature
Abstract
Traditionally, arthroscopic microfracture and autologous osteochondral autograft transplantation have been the primary surgical treat- ments for osteochondral lesions of the talus. On the other hand, recent advancements have introduced alternative approaches, such as autologous chondrocyte transplantation, matrix-derived autologous chondrocyte transplantation, intra-articular injection of concen- trated bone marrow aspirate concentrate, and the use of fibrin glue to address chondral defects. Furthermore, some studies have ex- plored a combination of bone marrow aspirate and matrix-derived chondrogenesis. In light of these developments, this report presents a case study of a young male patient in his early twenties with a relatively large osteochondral lesion exceeding 1.5 cm2 on the medial talar dome. Instead of removing the osteochondral lesion, a surgical approach was employed to retain the lesion while addressing the unstable cartilage in the affected area. This approach involved a combination of bone marrow aspirate concentrate and matrix-derived chondro- genesis. The treatment yielded favorable clinical outcomes and ultimately successfully induced the bony union of osteochondral lesions. This paper reports the author’s experience with this innovative approach with a review of the relevant literature
참고문헌 (10)
- Woo Jin Choi, "Osteochondral lesion of the talus: is there a critical defect size for poor outcome?", The American Journal of Sports Medicine, 37(10), pp.1974~1980 (2009), SAGE Publications[DOI]
- J. P. Benthien, "Autologous matrix-induced chondrogenesis (AMIC): combining microfracturing and a collagen I", III matrix for articular cartilage resurfacing, 2010, pp.1(1), 65~68[DOI]
- 김범수, "거골 골연골병변에 대한 수술적 치료: 골수 흡인물 농축액 및 기질 유래 연골 형성", 대한족부족관절학회지, 24(2), pp.61~68 (2020), 대한족부족관절학회[DOI]
- Daniel Corr, "Long-term Outcomes of Microfracture for Treatment of Osteochondral Lesions of the Talus", Foot Ankle Int, 42(7), pp.833~840 (2021), SAGE Publications[DOI]
- Henning Madry, "Bone Marrow Aspirate Concentrate-Enhanced Marrow Stimulation of Chondral Defects", Stem Cells International, 2017, pp.1~13 (2017), Hindawi Limited[DOI]
- Evelyn P. Murphy, "A prospective evaluation of bone marrow aspirate concentrate and microfracture in the treatment of osteochondral lesions of the talus", Foot and Ankle Surgery, 25(4), pp.441~448 (2019), Elsevier BV[DOI]
- Martin Volz, "A randomized controlled trial demonstrating sustained benefit of Autologous Matrix-Induced Chondrogenesis over microfracture at five years", International Orthopaedics, 41(4), pp.797~804 (2017), Springer Science and Business Media LLC[DOI]
- Francesca Vannini, "Return to Sports After Bone Marrow–Derived Cell Transplantation for Osteochondral Lesions of the Talus", CARTILAGE, 8(1), pp.80~87 (2016), SAGE Publications[DOI]
- Martinus Richter, "Matrix-associated stem cell transplantation (MAST) in chondral lesions at the ankle as part of a complex surgical approach- 5-year-follow-up in 100 patients", Foot and Ankle Surgery, 25(3), pp.264~271 (2019), Elsevier BV[DOI]
- Raghu Teja Sadineni, "Imaging Patterns in MRI in Recent Bone Injuries Following Negative or Inconclusive Plain Radiographs", JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 9, pp.TC10~TC13 (2015), JCDR Research and Publications[DOI]