비중격만곡증시 발생하는 하비갑개 대상성 비대의 조직학적 소견

Abstract

Background and Objectives：Deviation of the nasal septum toward one side is often asociated with an outgrowth of the inferior turbinate, which occupies the expansive space of the contralateral nasal cavity. It is assumed that this contrabalanced mechanism characterized by compensatory hypertrophy has originated to protect the more patent nasal side from excesive airflow with its drying and crusting efect. We tried to investigate histologic differences of inferior turbinate mucosa of both Materials and Method：Specimens were taken from the anterior portion of inferior turbinates of 15 patients with deviated nasal septum and compensatory hypertrophy of the inferior turbinate. After staining by hematoxylin-eosin, the histologic diferences of bilateral turbinate mucosa were examined under light microscope. Results：Epithelia of both sides showed normal or epithelial exfoliation. The number of submucosal glands was significantly higher in the opposite side than in the hypertrophied side. Inflamatory cell infiltration was more severe in the hypertrophied side than in the opposite side. Conclusion：Above results suggest that heavy infiltration of inflamatory cells and decreased number of glands in the hypertrophied side might result from aerodynamic change originated from diference of area of airway. (Korean J Otolaryngol 2003 ;46 :230-3)