한국의 도시지역에서 바퀴벌레 항원에 의한 알레르기비염：감작률과 진단
Cockroach Allergic Rhinitis in the Urban Area in Korea：Sensitivity and Diagnosis
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Abstract
Background and Objectives：Recently persistent type and mixed sensitization of allergic rhinitis are on the rise. We have frequently experienced patients sensitized to cockroach in allergic skin test (AST). There was a report that cockroach was prevalent in each house within Seoul metropolitan area. The aim of this study is to investigate the prevalence of patients sensitized to cockroach and to compare AST positivity to cockroach with multiple allergosorbent chemiluminescent asay (MAST-CLA) result. Subjects and Method：Alergic skin test with 5 comon inhalant alergens was performed in 180 patients who had visited Alergic Clinic of Kyung-Hee University Hospital from Jan. 2003 to Jul. 2003. Among them, MAST-CLA was performed itized patients with negative result in MAST. Results：54 patients (30% ) were AST positive to cockroach among 180 patients had allergic rhinitis. Concomitant ofending antigen were D. farinae (63% ), House dust (33.3%), Candida (13% ), Aspergillus (9.3%). on MAST. Minor bands of cockroach antigen in Western blot were detected in 6 of 10 patients who were sensitized to cockroach in AST but not to MAST. Conclusion：We suggest that cockroach should be considered as an important antigen in allergic rhinitis. It should be neded for the diagnosis of cockroach allergic rhinitis that MAST sensitivity is increased.
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