두경부에 생긴 과립세포종 9예
Granular Cell Tumors of the Head and Neck:A Case Report of 9 Cases
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Abstract
Granular cell tumor (GCT) is a rather uncommon neoplasm. Though GCTs are usually small, solitary and benign in most cases,a small number (1-2%) of cases are malignant. They can originate from anywhere in the body but are most frequently found in thehead and neck, particularly in an oral cavity. Histopathologically, GCT is composed of large, round, or polygonal cells with smalldense nuclei. Cytoplasm contains abundant eosinophilic granules. In an immunohistochemical study, granules of GCT are positivefor S-100 protein. Surgical intervention, wide excision with enough margin, is the treatment modality of choice. Inadequateresection of a tumor may result in local recurrence, even with a benign GCT. We have experienced 9 cases of GCT betweenDecember 1997 and June 2003, and report on them with a review of literatures.
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