본문 바로가기
KERD
논문KCI 등재

두경부암 환자에서 루골용액을 이용한 식도 내시경 선별검사

Endoscopic Screening of Esophagus with Lugol’s Solutionin Patients with Head and Neck Cancer

이강대|이환호|이형신|홍종철|하남욱|박선자
대한이비인후과학회 (Korean Society of Otorhinolaryngology-Head and Neck Surgery)|2006.10|대한이비인후과학회지 두경부외과학 (Korean Journal of Otorhinolaryngology-Head and Neck Surgery)|제49권 제10호|pp. 1008-1013

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

두경부암·이차 원발암·루골용액.Head and neck cancer·Second primary·Lugol’s solution.
주제분류이비인후과학

초록

Abstract

Background and Objectives：Second primary esophageal cancer has been reported to comprise 6-9% of head and neckcancer cases, which are frequently detected in the advanced stage. Thus, detecting esophageal cancer in the early stage is importantin the prognosis of head and neck cancer. However, it is difficult to detect early lesions using the conventional endoscopy.In the current study, the feasibility of endoscopic screening using Lugols solution was assessing for detecting early esophagealcancer in patients of head and neck cancer. Subjects and Method：Sixty-two patients (Group I-synchronous cancer studygroup) diagnosed with head and neck cancer between November, 2003 and November, 2004 were prospectively studied. Fortysixpatients (Group II-metachronous cancer study group) under the follow-up care with head and neck cancer during the sameperiod were also evaluated. The esophagus was initially observed under direct endoscopic view and then Lugol dye was sprayedat the esophagus. Any unstained area was biopsied. Results：Of 34 patients (54.8%) with unstained lesions in Group I, 10(16.1%) showed dysplasia and 4 (6.4%) had cancer. Of 21 patients (45.6%) with unstained lesions in Group II, 2 (4.3%)showed dysplasia and 5 (10.8%) had cancer. Among 9 (8.3%) second primary esophageal cancer, 6 were detected with superficialesophageal cancer while the other 3 were found to be in the advanced stage of cancer. This superficial cancer revealed nonspecificmucosal findings in the direct endoscopic view and was difficult to be visualized as a pathologic lesion; however, itrevealed unstained areas when Lugol’s solution was sprayed, thus could be diagnosed as cancer through biopsy of the area.Conclusion：Endoscopy of esophagus with Lugol’s solution could be highly effective as a screening method to detect secondprimary esophageal cancer in patients with head and neck cancer. (Korean J Otolaryngol 2006;49:1008-13)

참고문헌 (20)

  1. "Multiple primary cancer inpatients with cancer of the head and neck Second cancer of the headand neck", pp.467~76
  2. "Secondary primary malignancies in headand neck squamous cell carcinoma", 115, pp.988~991 (2001)
  3. "Smoking and drinking in relation to cancers of the oral cavity and esophagus in Northern Italy", serrai(d), pp.6502~7
  4. "Secondneoplasm in patients with head and neck cancer", 21, pp.204~210 (1999)
  5. "Subsequent upper aerodigestivemalignancies following treatment of esophageal cancer", 55, pp.1882~5 (1985)
  6. "Role of Lugol dye endoscopy in the diagnosis of early esophagealcancer", 22, pp.12~6 (1990)
  7. "Endoscopicdetection of early esophageal cancer in a high-risk population:Does Lugol staining improve videoendoscopy?", 45, pp.480~484 (1997)
  8. "Endoscopic examination of the upper gastrointestinaltract for the presence of second primary cancers in head and neckcancer patients", 501, pp.103~6 (1993)
  9. "Second primary tumors in patients with head and neck squamous cellcarcinoma", 75, pp.1343~1353 (1995)
  10. "Survival in second primary malignancies of patientswith head and neck cancer", 116, pp.831~838 (2002)
  11. "Associationof multiple Lugol-voiding lesions with synchronous andmetachronous esophageal squamous cell carcinoma in patients withhead and neck cancer", 56, pp.517~521 (2002)
  12. "Diagnosis of superficial esophageal cancer and dysplasiausing endoscopic screening with a 2% Lugol dye solution inpatients with head and neck cancer", 22, pp.170~174 (2000)
  13. "Endoscopic screening of early esophageal cancer with theLugol dye method in patients with head and neck cancers", 66, pp.2068~71 (1990)
  14. "Pathologic basis of disease" (1996), WBSounders
  15. "Pathology of incipient neoplasia", pp.64~71 (1994)
  16. "How can we diagnose the earlystage of esophageal cancer", endoscopic diag(sis), pp.11~8
  17. "Lugol-combinedendoscopic detection of minute malignant lesions of the thoracicesophagus", 208, pp.179~83 (1988)
  18. "Clinical implications of multicentric origin", pp.963~8
  19. "Radiotherapy for oral cancer as a risk factor for second primarycancers", 220, pp.185~195 (2005)
  20. "Multiple primary cancer in patients with esophagealcancer", 38, pp.264~271 (2003)

관련 논문AI추천

Endoscopy under general anesthesia for detecting synchronous lesions of head and neck squamous cell carcinomaDo Hoon Kim, Jin Hee Noh대한소화기내시경학회 · Clinical Endoscopy2023 · 제56권 제3호Clinical Significance of Early Detection of Esophageal Cancer in Patients with Head and Neck Cancer임현, 공은정, 김도훈, 김미영, 김진호, 나희경, 송호준, 안지영, 이정훈, 이진혁, 정훈용, 최기돈, 최기숙거트앤리버 소화기연관학회협의회 · Gut and Liver2015 · 제9권 제2호Usefulness of Probe-Based Confocal Laser Endomicroscopy for Esophageal Squamous Cell Neoplasm이상길대한소화기내시경학회 · Clinical Endoscopy2019 · 제52권 제2호구강암 경부임파절 전이에 대한 술전 평가의 정확성남웅, 이재준, 차인호대한구강악안면외과학회 · 대한구강악안면외과학회지2006 · 제32권 제2호Bimodal Chromoendoscopy with Confocal Laser Endomicroscopy for the Detection of Early Esophageal Squamous Cell NeoplasmsAnapat Sanpavat, Piyapan Prueksapanich, Rapat Pittayanon, Rungsun Rerknimitr, Thanawat Luangsukrerk대한소화기내시경학회 · Clinical Endoscopy2019 · 제52권 제2호Efficacy of endoscopy under general anesthesia for the detection of synchronous lesions in oro-hypopharyngeal cancerAkihiro Koga, Akinori Iwashita, Atsuko Ota, Hiroshi Tanabe, Kensei Ohtsu, Kenshi Yao, Kentaro Imamura, Masaki Miyaoka, Rumie Wakasaki, Satoshi Ishikawa, Satoshi Nimura, Seiji Haraoka, Susumu Sato, Takao Kanemitsu, Takashi Hisabe, Toshiharu Ueki, Yasuhiro Takaki, Yoichiro Ono대한소화기내시경학회 · Clinical Endoscopy2023 · 제56권 제3호

이 간행물의 다른 논문 (10건)

제2형 당뇨환자에서 발생한 돌발성 난청의 치료제로서 Lipo-Prostalandin E₁의 효능분석윤태현, 이광선, 김영진, 김태용, 정종우, 안중호, 한명월pp. 973-977상기도 폐색이 지속성 비강기도양압술 치료에 미치는 영향김효열, 홍상덕, 복권효, 민진영, 이우영, 정영준, 정승규, 동헌종pp. 986-990ARIA(Allergic Rhinitis and its Impact on Asthma)지침에서제시한 알레르기비염의 새 분류 기준에 따른 알레르기비염의 분석：혈청내 항원특이항체검사에 의한 검출 항원에 따른 분류법과 비교김성완, 여승근, 조중생, 이선규pp. 991-996소아 재발성 만성 부비동염 환자에 있어서 국소적 항생제 분무 치료의 효과민경근, 김선태, 김선영, 강일규, 차흥억pp. 997-1002OK-432를 이용한 하마종의 경화 요법김효선, 노종렬pp. 1003-1007
원문 보기