하시모토 갑상선염과 동반된 갑상선 유두상 암종의 임상적 의의
Clinical Assessment and Management of Papillary Thyroid Carcinomawith Coexistent Hashimoto’s Thyroiditis
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Abstract
Background and Objectives：The frequency of co-ocurence of Hashimotos thyroiditis and papillary thyroid carcinoma has ben variously reported to range from 0.3% to 38%, and the asociation of these two diseases is still controversial. The aim of cs of patients with and without histopathological evidence of Hashimotos thyroiditis. Subjects and Method：Among 366 patients treated for thyroid nodules (including benign nodules and thyroid cancers) during the period of July 2004 - June 2005, 278 patients (male versus female= 1 : 7.9) with papillary thyroid carcinoma were included in this study. Results：Hashimotos thyroiditis co-ocurred with papillary thyroid carcinoma in 68 of (24.5%), compared with 0 of 21 patients (0% ) with other thyroid malignancies. The age at presentation (median, 43.9 years), tumor size (median, 1.31 cm), methods of diag-nostic evaluation, and the extent of surgery had not influenced by the presence of Hashimotos thyroiditis. However, TNM stage, AMES stage, MACIS score were slightly lower and the proportion of female patients (1：67) was higher in patients with Conclusion：These results sugest that patients who have papillary thyroid carcinoma may have more favorable prognosis in the co-ocurring Hashimotos thyroiditis. Further studies are required to confirm the long-term prognostic association betwen these two diseases. (Korean J Otolaryngol 2007 ;50 :537-41)
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