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갑상선에서 발생한 편평상피세포-유두상 동시 암종 1예

A Case of Synchronous Squamous Cell and Papillary Carcinoma of the Thyroid Gland

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초록

The simultaneous occurrence of two distinct neoplasms derived from different cells of origin is sometimes recognized. In the thyroid gland, two such distinct tumors could consist of a concurrent squamous cell carcinoma and well-differentiated carcinoma showing follicular epithelial cell differentiation. Because the squamous cell carcinoma is characterized by rapidly progressive clinical course in spite of its differentiated morphologic feature, the tumor should be treated more vigorously at its initial stage. We report a rare, interesting case of concurrent squamous cell and papillary carcinoma of the thyroid gland. A 69-year-old male underwent a total thyroidectomy, central neck dissection and bilaterally modified radical neck dissection, which was diagnosed as papillary carcinoma by ultrasonography-guided aspiration cytology. The pathological report of the surgical specimen of the thyroid gland revealed synchronous squamous cell carcinoma and papillary carcinoma. He received local radiotherapy but died of pneumonia eight months after surgery. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:1065-7)

Abstract

The simultaneous occurrence of two distinct neoplasms derived from different cells of origin is sometimes recognized. In the thyroid gland, two such distinct tumors could consist of a concurrent squamous cell carcinoma and well-differentiated carcinoma showing follicular epithelial cell differentiation. Because the squamous cell carcinoma is characterized by rapidly progressive clinical course in spite of its differentiated morphologic feature, the tumor should be treated more vigorously at its initial stage. We report a rare, interesting case of concurrent squamous cell and papillary carcinoma of the thyroid gland. A 69-year-old male underwent a total thyroidectomy, central neck dissection and bilaterally modified radical neck dissection, which was diagnosed as papillary carcinoma by ultrasonography-guided aspiration cytology. The pathological report of the surgical specimen of the thyroid gland revealed synchronous squamous cell carcinoma and papillary carcinoma. He received local radiotherapy but died of pneumonia eight months after surgery. (Korean J Otorhinolaryngol-Head Neck Surg 2008;51:1065-7)

참고문헌 (14)

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