이하선에 발생한 염증성 근육섬유모세포종 1예
Inflammatory Myofibroblastic Tumor of the Parotid Gland
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Inflammatory myofibroblastic tumor (IMT), which is composed of spindle shaped myofibroblasts accompanied by an inflammatory infiltrate, is an uncommon neoplasm. Herein we present a rare case of an IMT of the parotid gland. The patient was a 56-year-old woman with parotid mass, which developed a tingling sensation around the mouth angle when the mass was palpated. Ultrasound and CT scan showed a parotid mass with an ill-defined margin. Preoperative gun biopsy showed spindle shaped cell proliferation without cytological atypia. Surgery revealed that the mass was adhesive to buccal branch of facial nerve without encapsulation. The adhesive part of the facial nerve was excised with mass due to the possibility of malignancy. The final pathological report confirming IMT became available following the surgery. We stress that confirmation of IMT should be included in the differential diagnosis of parotid mass which shows spindle shaped cells in histology.
Abstract
Inflammatory myofibroblastic tumor (IMT), which is composed of spindle shaped myofibroblasts accompanied by an inflammatory infiltrate, is an uncommon neoplasm. Herein we present a rare case of an IMT of the parotid gland. The patient was a 56-year-old woman with parotid mass, which developed a tingling sensation around the mouth angle when the mass was palpated. Ultrasound and CT scan showed a parotid mass with an ill-defined margin. Preoperative gun biopsy showed spindle shaped cell proliferation without cytological atypia. Surgery revealed that the mass was adhesive to buccal branch of facial nerve without encapsulation. The adhesive part of the facial nerve was excised with mass due to the possibility of malignancy. The final pathological report confirming IMT became available following the surgery. We stress that confirmation of IMT should be included in the differential diagnosis of parotid mass which shows spindle shaped cells in histology.
참고문헌 (15)
- Gleason BC, "Inflammatory myofibroblastic tumours: where are we now?", J Clin Pathol, 61(4), pp.428~437 (2008)
- Ong HS, "Head and neck inflammatory myofibroblastic tumor (IMT): evaluation of clinicopathologic and prognostic features", Oral Oncol, 48(2), pp.141~148 (2012)
- Chen YF, "Inflammatory myofibroblastic tumor of the head and neck", Med Oncol, 28(Suppl 1), pp.S349~S353 (2011)
- 우현재, "성대 용종으로 오인된염증성 근섬유모세포종 1예", 대한이비인후과학회지 두경부외과학, 51(2), pp.206~208 (2008), 대한이비인후과학회
- 조재구, "비강에 발생한 염증성 근육섬유모세포종 1예", 대한이비인후과학회지 두경부외과학, 52(12), pp.1005~1008 (2009), 대한이비인후과학회
- 우현재, "8세 여아 비강에서 발생한 염증성 근섬유모세포종 1예", 대한이비인후과학회지 두경부외과학, 51(5), pp.481~483 (2008), 대한이비인후과학회
- Monteil RA, "Oral inflammatory pseudotumour: immunohistochemical investigation of a case involving the submandibular gland and review of the literature", Oral Oncol, 33(3), pp.215~219 (1997)
- Van Weert S, "Inflammatory myofibroblastic tumor of the parotid gland: case report and review of the literature", Acta Otolaryngol, 125(4), pp.433~437 (2005)
- Qiu X, "Inflammatory myofibroblastic tumor and low-grade myofibroblastic sarcoma: a comparative study of clinicopathologic features and further observations on the immunohistochemical profile of myofibroblasts", Hum Pathol, 39(6), pp.846~856 (2008)
- Ramachandra S, "Inflammatory pseudotumour of soft tissues: a clinicopathological and immunohistochemical analysis of 18 cases", Histopathology, 27(4), pp.313~323 (1995)
- Olsen KD, "Tumefactive fibroinflammatory lesions of the head and neck", Laryngoscope, 96(9 Pt 1), pp.940~944 (1986)
- Williams SB, "Inflammatory pseudotumors of the major salivary glands. Clinicopathologic and immunohistochemical analysis of six cases", Am J Surg Pathol, 16(9), pp.896~902 (1992)
- Inui M, "Inflammatory pseudotumor in the submandibular region. Clinicopathologic study and review of the literature", Oral Surg Oral Med Oral Pathol, 76(3), pp.333~337 (1993)
- Cross DL, "Fibroinflammatory pseudotumor of the submandibular gland", Head Neck, 18(5), pp.465~468 (1996)
- Kojima M, "Inflammatory pseudotumor of the submandibular gland: report of a case presenting with autoimmune disease-like clinical manifestations", Arch Pathol Lab Med, 125(8), pp.1095~1097 (2001)