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다발성 하부 뇌신경마비를 동반한 중심성 뇌기저부 골수염 1예

A Case of Central Skull Base Osteomyelitis Concurrent with Multiple Lower Cranial Nerve Palsies

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키워드

주제분류이비인후과학

초록

In most cases, skull base osteomyelitis arises from infections of external auditory canal, middle ear or paranasal sinuses. On the other hand, atypical or central skull base osteomyelitis has no evidence of external otitis or other infection sources. It is often found located on clivus and involves lower cranial nerves and brainstem through the foramina of skull base. The overall rate of mortality reaches 10% and long-term neurologic sequelae are seen in additional 31% of cases regardless of aggressive treatment. We recently encountered a 68-year-old man with right facial pain and generalized headache, and we achieved good outcome with the recovery of vocal cord palsy and disappearance of headache by surgical debridement and long-term antibiotics. We report it with a review of literature. Korean J Otorhinolaryngol-Head Neck Surg 2014;57(7):489-92

Abstract

In most cases, skull base osteomyelitis arises from infections of external auditory canal, middle ear or paranasal sinuses. On the other hand, atypical or central skull base osteomyelitis has no evidence of external otitis or other infection sources. It is often found located on clivus and involves lower cranial nerves and brainstem through the foramina of skull base. The overall rate of mortality reaches 10% and long-term neurologic sequelae are seen in additional 31% of cases regardless of aggressive treatment. We recently encountered a 68-year-old man with right facial pain and generalized headache, and we achieved good outcome with the recovery of vocal cord palsy and disappearance of headache by surgical debridement and long-term antibiotics. We report it with a review of literature. Korean J Otorhinolaryngol-Head Neck Surg 2014;57(7):489-92

참고문헌 (12)

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  3. Johnson AK, "Central skull base osteomyelitis: an emerging clinical entity", Laryngoscope, 124(5), pp.1083~1087 (2014)
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  10. Noyek AM, "The clinical significance of radionuclide bone and gallium scanning in osteomyelitis of the head and neck", Laryngoscope, 94(5 PT 2 Suppl 34), pp.1~21 (1984)
  11. 김보영, "침윤성 Candida 감염에 의한 뇌기저 골수염 2예", 대한이비인후과학회지 두경부외과학, 49(7), pp.743~746 (2006), 대한이비인후과학회
  12. Patmore H, "Skull base infection presenting with multiple lower cranial nerve palsies", Am J Otolaryngol, 31(5), pp.376~380 (2010)

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