속발성으로 발생한 인체유두종바이러스 연관 두경부 이차암 1예
A Case of Metachronous Human Papilloma Virus-Associated Squamous Cell Carcinomas in Head and Neck
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Synchronous or metachronous head and neck cancer is known to occur in up to 20% of patients, negatively affecting long-term prognosis. We experienced a case of metachronous head and neck cancers in a Human papillomavirus (HPV)-positive patient without a history of smoking, initially presenting with as a cancer of unknown primary (CUP), and then with a contralateral tonsil cancer with metastatic lymphadenopathy five years later. This report highlights the clinical usefulness of HPV typing to determine the optimal extent of surgery and the follow-up strategy in CUP. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(3):233-7
Abstract
Synchronous or metachronous head and neck cancer is known to occur in up to 20% of patients, negatively affecting long-term prognosis. We experienced a case of metachronous head and neck cancers in a Human papillomavirus (HPV)-positive patient without a history of smoking, initially presenting with as a cancer of unknown primary (CUP), and then with a contralateral tonsil cancer with metastatic lymphadenopathy five years later. This report highlights the clinical usefulness of HPV typing to determine the optimal extent of surgery and the follow-up strategy in CUP. Korean J Otorhinolaryngol-Head Neck Surg 2016;59(3):233-7
참고문헌 (15)
- Erkal HS, "Synchronous and metachronous squamous cell carcinomas of the head and neck mucosal sites", J Clin Oncol, 19(5), pp.1358~1362 (2001)
- Slaughter DP, "Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin", Cancer, 6(5), pp.963~968 (1953)
- Fakhry C, "Clinical implications of human papillomavirus in head and neck cancers", J Clin Oncol, 24(17), pp.2606~2611 (2006)
- 정유석, "두경부암에서 인유두종바이러스의 의미: 몇 가지 질문들", 대한이비인후과학회지 두경부외과학, 57(3), pp.143~150 (2014), 대한이비인후과학회[DOI]
- Huang SH, "Atypical clinical behavior of p16-confirmed HPV-related oropharyngeal squamous cell carcinoma treated with radical radiotherapy", Int J Radiat Oncol Biol Phys, 82(1), pp.276~283 (2012)
- Joseph AW, "Molecular etiology of second primary tumors in contralateral tonsils of human papillomavirus-associated index tonsillar carcinomas", Oral Oncol, 49(3), pp.244~248 (2013)
- McGovern SL, "Three synchronous HPV-associated squamous cell carcinomas of Waldeyer’s ring: case report and comparison with Slaughter’s model of field cancerization", Head Neck, 32(8), pp.1118~1124 (2010)
- Schwartz LH, "Synchronous and metachronous head and neck carcinomas", Cancer, 74(7), pp.1933~1938 (1994)
- Caley A, "Multicentric human papillomavirus-associated head and neck squamous cell carcinoma", Head Neck, 37(2), pp.202~208 (2015)
- Grau C, "Cervical lymph node metastases from unknown primary tumours. Results from a national survey by the Danish Society for Head and Neck Oncology", Radiother Oncol, 55(2), pp.121~129 (2000)
- 안영진, "원발부위미상 경부 전이암의 진단 및 치료, 예후에 대한 고찰", 대한이비인후과학회지 두경부외과학, 50(12), pp.1125~1129 (2007), 대한이비인후과학회
- Mahoney EJ, "Evaluation and management of malignant cervical lymphadenopathy with an unknown primary tumor", Otolaryngol Clin North Am, 38(1), pp.87~97 (2005)
- Paz IB, "Human papillomavirus (HPV) in head and neck cancer. An association of HPV 16 with squamous cell carcinoma of Waldeyer’s tonsillar ring", Cancer, 79(3), pp.595~604 (1997)
- Kreimer AR, "Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review", Cancer Epidemiol Biomarkers Prev, 14(2), pp.467~475 (2005)
- Koch WM, "Oncologic rationale for bilateral tonsillectomy in head and neck squamous cell carcinoma of unknown primary source", Otolaryngol Head Neck Surg, 124(3), pp.331~333 (2001)