심경부 감염환자의 수술적 치료 결정의 예측인자로서 C-반응단백과 고혈압의 의의: 후향적 코호트 연구
C-Reactive Protein and High Blood Pressure are the Predictive Factors of Deciding the Surgical Treatment in Deep Neck Infection: A Retrospective Cohort Study
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Background and Objectives In clinical settings, some deep neck infections may be managedby conservative treatment but some still require surgical treatment. In this study, we useunivariate and multivariate analysis to discuss whether or not there are significant differencesbetween conservative treatment and surgical treatment on patients with deep neck infections. Subjects and Method We conducted a retrospective analysis using medical records of 88patients with deep neck infections from January 2010 to December 2015. Among 88 patients,56 patients were managed by conservative treatment with antibiotics and 32 patients weremanaged by surgical treatment via transcervical approach with antibiotics. As for data analysis,Mann-Whitney U test and multiple logistic regression analysis was used. Results Age, duration from symptom onset to hospitalization, hospital days, incidence ofunderlying disease, white blood cell count, erythrocyte sedimentation rate, and C-reactive protein(CRP) were found higher in the surgical treatment group than in the conservative treatmentgroup. But there was no statistical significance except for the incidence of high blood pressureand CRP. Conclusion CRP and incidence of high blood pressure were significant predictive factorsfor choosing the surgical treatment in deep neck infection. Contrary to our expectations, the incidenceof diabetes mellitus was not a significant factor that determined the treatment optionsfor the patients with deep neck infection.
Abstract
Background and Objectives In clinical settings, some deep neck infections may be managedby conservative treatment but some still require surgical treatment. In this study, we useunivariate and multivariate analysis to discuss whether or not there are significant differencesbetween conservative treatment and surgical treatment on patients with deep neck infections. Subjects and Method We conducted a retrospective analysis using medical records of 88patients with deep neck infections from January 2010 to December 2015. Among 88 patients,56 patients were managed by conservative treatment with antibiotics and 32 patients weremanaged by surgical treatment via transcervical approach with antibiotics. As for data analysis,Mann-Whitney U test and multiple logistic regression analysis was used. Results Age, duration from symptom onset to hospitalization, hospital days, incidence ofunderlying disease, white blood cell count, erythrocyte sedimentation rate, and C-reactive protein(CRP) were found higher in the surgical treatment group than in the conservative treatmentgroup. But there was no statistical significance except for the incidence of high blood pressureand CRP. Conclusion CRP and incidence of high blood pressure were significant predictive factorsfor choosing the surgical treatment in deep neck infection. Contrary to our expectations, the incidenceof diabetes mellitus was not a significant factor that determined the treatment optionsfor the patients with deep neck infection.
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