양성 돌발두위현훈의 재발 요인 분석: 11년간의 국민건강보험공단 표본 코호트 연구
Analysis of Risk Factors for Recurrence of Benign Paroxysmal Positional Vertigo: An 11-Year Nationwide Population-Based Study
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Background and Objectives Benign paroxysmal positional vertigo (BPPV) is one of the mostcommon causes of dizziness with a high recurrence rate. This study aimed to analyze the recurrencerate and the risk factors for recurrence using the Korean National Health Insurance ServiceNational Sample Cohort (NHIS-NSC 2002-2013) data. Subjects and Method Patients aged 20 years or older who were diagnosed with BPPV inthe period of 2002-2012 and had at least 1 year of monitoring period were included in this study. The diagnosis of BPPV was made when the code for BPPV (KCD-6 code H811) was used orwhen canalith reposition therapy (EDI code MX035) was entered even in cases with differentdiagnoses. The risk factors of BPPV recurrence were analyzed. Results Of the total of 21355 patients diagnosed with BPPV, 5876 patients (28%) demonstratedrecurrence. Multiple recurrences were common. When using the univariate regression analysis,age, sex, vestibular disease, headache, osteoporosis, and ischemic heart disease were foundsignificant. When the patients were classified into 4 groups according to age and sex, vestibulardiseases were found as a common risk factor for recurrence in all groups, while headache,osteoporosis, hypertension, and ischemic heart disease were significant in females. Conclusion The recurrence rate of BPPV in the Korean adult population was approximately28% and recurrences were more common in patients aged over 65 and in females. Patients withvestibular diseases were at a higher risk of recurrence regardless of age or sex, while headache,osteoporosis, hypertension and ischemic heart disease increased the risk of recurrence in females.
Abstract
Background and Objectives Benign paroxysmal positional vertigo (BPPV) is one of the mostcommon causes of dizziness with a high recurrence rate. This study aimed to analyze the recurrencerate and the risk factors for recurrence using the Korean National Health Insurance ServiceNational Sample Cohort (NHIS-NSC 2002-2013) data. Subjects and Method Patients aged 20 years or older who were diagnosed with BPPV inthe period of 2002-2012 and had at least 1 year of monitoring period were included in this study. The diagnosis of BPPV was made when the code for BPPV (KCD-6 code H811) was used orwhen canalith reposition therapy (EDI code MX035) was entered even in cases with differentdiagnoses. The risk factors of BPPV recurrence were analyzed. Results Of the total of 21355 patients diagnosed with BPPV, 5876 patients (28%) demonstratedrecurrence. Multiple recurrences were common. When using the univariate regression analysis,age, sex, vestibular disease, headache, osteoporosis, and ischemic heart disease were foundsignificant. When the patients were classified into 4 groups according to age and sex, vestibulardiseases were found as a common risk factor for recurrence in all groups, while headache,osteoporosis, hypertension, and ischemic heart disease were significant in females. Conclusion The recurrence rate of BPPV in the Korean adult population was approximately28% and recurrences were more common in patients aged over 65 and in females. Patients withvestibular diseases were at a higher risk of recurrence regardless of age or sex, while headache,osteoporosis, hypertension and ischemic heart disease increased the risk of recurrence in females.
참고문헌 (26)
- Bhattacharyya N, "Clinical practice guideline: benign paroxysmal positional vertigo", Otolaryngol Head Neck Surg, 139(5 Suppl 4), pp.S47~S81 (2008)
- Kim JS, "Clinical practice. benign paroxysmal positional vertigo", N Engl J Med, 370(12), pp.1138~1147 (2014)
- Pérez P, "Recurrence of benign paroxysmal positional vertigo", Otol Neurotol, 33(3), pp.437~443 (2012)
- Kim SH, "A cupulolith repositioning maneuver in the treatment of horizontal canal cupulolithiasis", Auris Nasus Larynx, 39(2), pp.163~168 (2012)
- Choi SJ, "Clinical features of recurrent or persistent benign paroxysmal positional vertigo", Otolaryngol Head Neck Surg, 147(5), pp.919~924 (2012)
- Simhadri S, "Efficacy of particle repositioning maneuver in BPPV : a prospective study", Am J Otolaryngol, 24(6), pp.355~360 (2003)
- Nunez RA, "Short-and long-term outcomes of canalith repositioning for benign paroxysmal positional vertigo", Otolaryngol Head Neck Surg, 122(5), pp.647~652 (2000)
- Brandt T, "Benign paroxysmal positioning vertigo : a long-term follow-up(6-17 years)of 125 patients", Acta Otolaryngol, 126(2), pp.160~163 (2006)
- De Stefano A, "A multicenter observational study on the role of comorbidities in the recurrent episodes of benign paroxysmal positional vertigo", Auris Nasus Larynx, 41(1), pp.31~36 (2014)
- Sakaida M, "Longterm outcome of benign paroxysmal positional vertigo", Neurology, 60(9), pp.1532~1534 (2003)
- Su P, "Risk factors for the recurrence of post-semicircular canal benign paroxysmal positional vertigo after canalith repositioning", J Neurol, 263(1), pp.45~51 (2016)
- Tanimoto H, "Risk factors for recurrence of benign paroxysmal positional vertigo", J Otolaryngol Head Neck Surg, 37(6), pp.832~835 (2008)
- National Health Insurance Service, "National health insurance statistical yearbook" (2014), Health Insurance Review and Assessment Service and National Health Insurance Service
- Picciotti PM, "Comorbidities and recurrence of benign paroxysmal positional vertigo : personal experience", Int J Audiol, 55(5), pp.279~284 (2016)
- Kansu L, "Long-term follow-up of patients with posterior canal benign paroxysmal positional vertigo", Acta Otolaryngol, 130(9), pp.1009~1012 (2010)
- Ishiyama G, "Imbalance and vertigo : the aging human vestibular periphery", Semin Neurol, 29(5), pp.491~499 (2009)
- Jang YS, "Age-related changes on the morphology of the otoconia", Laryngoscope, 116(6), pp.996~1001 (2006)
- Ogun OA, "Menopause and benign paroxysmal positional vertigo", Menopause, 21(8), pp.886~889 (2014)
- Yu S, "Association between osteoporosis and benign paroxysmal positional vertigo : a systematic review", BMC Neurol, 14, pp.110~ (2014)
- Yamanaka T, "Osteoporosis as a risk factor for the recurrence of benign paroxysmal positional vertigo", Laryngoscope, 123(11), pp.2813~2816 (2013)
- Jang YS, "Relationship between bone mineral density and clinical features in women with idiopathic benign paroxysmal positional vertigo", Otol Neurotol, 30(1), pp.95~100 (2009)
- Dornhoffer JL, "Benign paroxysmal positional vertigo and canalith repositioning : clinical correlations", Am J Otol, 21(2), pp.230~233 (2000)
- Ishiyama A, "Migraine and benign positional vertigo", Ann Otol Rhinol Laryngol, 109(4), pp.377~380 (2000)
- Vass Z, "Capsaicin stimulation of the cochlea and electric stimulation of the trigeminal ganglion mediate vascular permeability in cochlear and vertebro-basilar arteries : a potential cause of inner ear dysfunction in headache", Neuroscience, 103(1), pp.189~201 (2001)
- Jeong SH, "Osteopenia and osteoporosis in idiopathic benign positional vertigo", Neurology, 72(12), pp.1069~1076 (2009)
- Takemura T, "Localization of osteopontin in the otoconial organs of adult rats", Hear Res, 79(1-2), pp.99~104 (1994)