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비중격 천공에 의해 늦게 진단된 결절외 비성 Natural Killer/T 세포 림프종 1예

Delayed Diagnosis Due to Septal Perforation in Patient with Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type

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초록

Extranodal natural killer (NK)/T-cell lymphoma, nasal type is a rare non-Hodgkin lymphomaoriginating in the nasal cavity or in the paranasal sinuses, and is etiologically closely related withthe Epstein Barr Virus infection. It is more commonly found in East Asia, South America, andMexico than in Europe or North America. Extranodal NK/T-cell lymphoma, nasal type typicallyshows a crust on the nasal mucosal surface, necrosis, and inflammation. Pathologically, itpresents as significant vascular damage and destruction, with apparent tissue necrosis and cytotoxicity. These neoplasms are very aggressive and can show septal perforation, diffuse ulcer lesionon the nasal mucosa, fistula or epistaxis. We experienced a case of the extranodal NK/Tcelllymphoma, nasal type at the nasal septum, which was delayed in diagnosis due to septalperforation, which occurred after septoplasty in a 47-year-old female. Thus, we report this casewith a review of literatures.

Abstract

Extranodal natural killer (NK)/T-cell lymphoma, nasal type is a rare non-Hodgkin lymphomaoriginating in the nasal cavity or in the paranasal sinuses, and is etiologically closely related withthe Epstein Barr Virus infection. It is more commonly found in East Asia, South America, andMexico than in Europe or North America. Extranodal NK/T-cell lymphoma, nasal type typicallyshows a crust on the nasal mucosal surface, necrosis, and inflammation. Pathologically, itpresents as significant vascular damage and destruction, with apparent tissue necrosis and cytotoxicity. These neoplasms are very aggressive and can show septal perforation, diffuse ulcer lesionon the nasal mucosa, fistula or epistaxis. We experienced a case of the extranodal NK/Tcelllymphoma, nasal type at the nasal septum, which was delayed in diagnosis due to septalperforation, which occurred after septoplasty in a 47-year-old female. Thus, we report this casewith a review of literatures.

참고문헌 (11)

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