두피 혈관육종(Scalp Angiosarcoma)의 치료 성적: 단일 기관의 경험
Treatment Outcome of Scalp Angiosarcoma: A Single Institute Experience
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Background and Objectives Scalp angiosarcoma is a rare but aggressive vascular malignancy. It is often found in the advanced state and tends to cause distant metastasis at an earlystage. There is no consensus on a treatment modality, although wide excision followed by adjuvanttherapy is currently used. The purpose of this study was to analyze the treatment resultsand disease progress pattern of scalp angiosarcoma in a single institution. Subjects and Method We enrolled patients who diagnosed with scalp angiosarcoma atAsan Medical Center from March 2011 to September 2019. Disease course and prognostic factorswere analyzed by estimating overall survival rate and disease free survival. Results A total 12 patients were enrolled in this study. The median overall survival was 16.0months. The 3-year-survival rate was 10.6%, and the median disease free survival was 5.0months. On the average, it took 11.4 months till death after recurrence. Conclusion Although wide surgical excision and multiple adjuvant therapies are employed,scalp angiosarcoma showed frequent recurrences and metastasis which led to poor outcomes. Further investigations for scalp angiosarcoma are necessary to improve treatment outcomes.
Abstract
Background and Objectives Scalp angiosarcoma is a rare but aggressive vascular malignancy. It is often found in the advanced state and tends to cause distant metastasis at an earlystage. There is no consensus on a treatment modality, although wide excision followed by adjuvanttherapy is currently used. The purpose of this study was to analyze the treatment resultsand disease progress pattern of scalp angiosarcoma in a single institution. Subjects and Method We enrolled patients who diagnosed with scalp angiosarcoma atAsan Medical Center from March 2011 to September 2019. Disease course and prognostic factorswere analyzed by estimating overall survival rate and disease free survival. Results A total 12 patients were enrolled in this study. The median overall survival was 16.0months. The 3-year-survival rate was 10.6%, and the median disease free survival was 5.0months. On the average, it took 11.4 months till death after recurrence. Conclusion Although wide surgical excision and multiple adjuvant therapies are employed,scalp angiosarcoma showed frequent recurrences and metastasis which led to poor outcomes. Further investigations for scalp angiosarcoma are necessary to improve treatment outcomes.
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