노인성 어지럼증 진단 기준을 중심으로 한 나이에 따른 Vestibulo-Ocular Reflex 값의 차이
Age-Related Differences of Vestibulo-Ocular Reflex Gains Based on Presbyvestibulopathy Objective Criteria
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Background and Objectives With the growing acknowledgment of age-related vestibularimpairments, consensus diagnostic criteria for presbyvestibulopathy (PVP) have been recentlypublished. The PVP criteria retains its objectivity with video head impulse test (vHIT), rotatorychair test (RCT) and caloric test. These objective tests share testing principles, but targeted frequenciesvary across the tests. The PVP criteria are applicable for subjects of age over 60. However,there are different age cut-offs for older male in different areas. The purpose of the presentstudy was to explore whether the PVP diagnostic criteria were appropriate for early elderly(Eel) patients and to identify the most sensitive test for age-related loss of vestibular function. Subjects and Method Eligible patients, aged 60 years or older, complained of dizziness forat least 3 weeks, and have undergone at least one of the followings: vHIT, RCT, or caloric test. We selected two groups based on age: the Eel group (aged >60 years but <65 years) and the lateelderly (Lel) group (aged ≥75 years). Results The vestibulo-ocular reflex (VOR) gains differed significantly between the Eel andLel groups for vHIT and caloric gain test. No Eel patient met the PVP criteria but 26.1% of Lelpatients met the criteria for vHIT, and the proportions of such patients in the two groups differedsignificantly. Conclusion Eel subjects could be considered to differ from Lel subjects. Given the significanceof both averages, VOR difference and the proportional difference in terms of meetingthe PVP criteria and vHIT may be optimal when evaluating age-related changes.
Abstract
Background and Objectives With the growing acknowledgment of age-related vestibularimpairments, consensus diagnostic criteria for presbyvestibulopathy (PVP) have been recentlypublished. The PVP criteria retains its objectivity with video head impulse test (vHIT), rotatorychair test (RCT) and caloric test. These objective tests share testing principles, but targeted frequenciesvary across the tests. The PVP criteria are applicable for subjects of age over 60. However,there are different age cut-offs for older male in different areas. The purpose of the presentstudy was to explore whether the PVP diagnostic criteria were appropriate for early elderly(Eel) patients and to identify the most sensitive test for age-related loss of vestibular function. Subjects and Method Eligible patients, aged 60 years or older, complained of dizziness forat least 3 weeks, and have undergone at least one of the followings: vHIT, RCT, or caloric test. We selected two groups based on age: the Eel group (aged >60 years but <65 years) and the lateelderly (Lel) group (aged ≥75 years). Results The vestibulo-ocular reflex (VOR) gains differed significantly between the Eel andLel groups for vHIT and caloric gain test. No Eel patient met the PVP criteria but 26.1% of Lelpatients met the criteria for vHIT, and the proportions of such patients in the two groups differedsignificantly. Conclusion Eel subjects could be considered to differ from Lel subjects. Given the significanceof both averages, VOR difference and the proportional difference in terms of meetingthe PVP criteria and vHIT may be optimal when evaluating age-related changes.
참고문헌 (20)
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