접형동에서 발생한 역형성 림프종 키나제 음성 역형성대세포림프종 1예
A Case of Anaplastic Lymphoma Kinase Negative Anaplastic Large Cell Lymphoma of Sphenoid Sinus
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초록
Anaplastic large cell lymphoma (ALCL) is a rare subtype of peripheral T cell lymphoma,which is clinically, pathologically, and genetically heterogeneous. The disease is characterizedby large CD30 positive anaplastic cells that usually have horseshoe or kidney-shaped nucleiand infiltrate lymph nodes. Given the rarity of ALCL and its non-specific symptoms, it ischallenging to consider a differential diagnosis at first; however, meticulous tissue biopsy andimmunohistochemical staining can diagnose it. Recently, we encountered a patient who com-plained of facial pain, trismus and numb of lip for three months and was diagnosed with ana-plastic lymphoma kinase negative ALCL of the sphenoid sinus. Here we report this rare casewith review literature.
Abstract
Anaplastic large cell lymphoma (ALCL) is a rare subtype of peripheral T cell lymphoma,which is clinically, pathologically, and genetically heterogeneous. The disease is characterizedby large CD30 positive anaplastic cells that usually have horseshoe or kidney-shaped nucleiand infiltrate lymph nodes. Given the rarity of ALCL and its non-specific symptoms, it ischallenging to consider a differential diagnosis at first; however, meticulous tissue biopsy andimmunohistochemical staining can diagnose it. Recently, we encountered a patient who com-plained of facial pain, trismus and numb of lip for three months and was diagnosed with ana-plastic lymphoma kinase negative ALCL of the sphenoid sinus. Here we report this rare casewith review literature.
참고문헌 (15)
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