Nystagmus Based Screening System for Vestibular Schwannoma in Patients With Asymmetric Hearing Loss
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Background and Objectives We conducted this study to propose a nystagmus based screen-ing system (NBSS) for detecting vestibular schwannoma (VS) in patients with asymmetric sen-sorineural hearing loss (ASNHL). Subjects and Method Data of 90 patients diagnosed with VS were retrospectively analysed. For the 1:1 allocation, 90 ASNHL patients who were not diagnosed with VS were sequentiallyenrolled as the non-VS group and retrospectively analysed. Every participant received puretone audiometry (PTA), a bedside vestibular function test, and magnetic resonance imaging. A total of 122 patients who passed the exclusion criteria were selected for the study. Results The sensitivity and specificity of the abnormal criteria of auditory brainstem re-sponse (ABR) for the detection of VS in patients (n=70) showing analyzable wave responsewere 80.0% and 52.0%, respectively. However, when we included all of the patients (n=122)who did not show analyzable wave response in ABR, the sensitivity and specificity of the ab-normal criteria decreased to 34.8% and 68.4%, respectively. NBSS is composed of verticalspontaneous nystagmus, direction changing gaze evoked nystagmus, ipsilesional monophasictype head shaking nystagmus (HSN), and ipsilesional to contralesional biphasic type HSN. The sensitivity and specificity of the NBSS were 56.5% and 82.9%, respectively. Conclusion NBSS may be used as a supplementary test to ABR in detecting VS of ASNHL.
Abstract
Background and Objectives We conducted this study to propose a nystagmus based screen-ing system (NBSS) for detecting vestibular schwannoma (VS) in patients with asymmetric sen-sorineural hearing loss (ASNHL). Subjects and Method Data of 90 patients diagnosed with VS were retrospectively analysed. For the 1:1 allocation, 90 ASNHL patients who were not diagnosed with VS were sequentiallyenrolled as the non-VS group and retrospectively analysed. Every participant received puretone audiometry (PTA), a bedside vestibular function test, and magnetic resonance imaging. A total of 122 patients who passed the exclusion criteria were selected for the study. Results The sensitivity and specificity of the abnormal criteria of auditory brainstem re-sponse (ABR) for the detection of VS in patients (n=70) showing analyzable wave responsewere 80.0% and 52.0%, respectively. However, when we included all of the patients (n=122)who did not show analyzable wave response in ABR, the sensitivity and specificity of the ab-normal criteria decreased to 34.8% and 68.4%, respectively. NBSS is composed of verticalspontaneous nystagmus, direction changing gaze evoked nystagmus, ipsilesional monophasictype head shaking nystagmus (HSN), and ipsilesional to contralesional biphasic type HSN. The sensitivity and specificity of the NBSS were 56.5% and 82.9%, respectively. Conclusion NBSS may be used as a supplementary test to ABR in detecting VS of ASNHL.
참고문헌 (30)
- Tos M, "What is the real incidence of vestibular schwannoma?", Arch Otolaryngol Head Neck Surg, 130(2), pp.216~220 (2004)
- Stangerup SE, "True incidence of vestibular schwannoma?", Neurosurgery, 67(5), pp.1335~1340 (2010)
- D’Haese S, "Vestibular schwannoma : Natural growth and possible predictive factors", Acta Otolaryngol, 139(9), pp.753~758 (2019)
- Scholte M, "Potential savings in the diagnosis of vestibular schwannoma", Clin Otolaryngol, 43(1), pp.285~290 (2018)
- Koors PD, "ABR in the diagnosis of vestibular schwannomas : A meta-analysis", Am J Otolaryngol, 34(3), pp.195~204 (2013)
- Park Marn Joon, "Diagnostic Validity of Auditory Brainstem Response for the Initial Screening of Vestibular Schwannoma", Journal of Audiology & Otology, 26(1), pp.36~42 (2022), 대한청각학회[DOI]
- Watson DR, "The effects of cochlear hearing loss, age and sex on the auditory brainstem response", Audiology, 35(5), pp.246~258 (1996)
- Li FJ, "Clinical study on 136 children with sudden sensorineural hearing loss", Chin Med J(Engl), 129(8), pp.946~952 (2016)
- Kraus N, "Absent auditory brain stem response : Peripheral hearing loss or brain stem dysfunction?", Laryngoscope, 94(3), pp.400~406 (1984)
- Zhang H, "Analyses of audiological examination in children without auditory brainstem response", Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 54(7), pp.540~543 (2019)
- Hain TC, "Head-shaking nystagmus in patients with unilateral peripheral vestibular lesions", Am J Otolaryngol, 8(1), pp.36~47 (1987)
- Kamei T, "The two-phase occurrence of head-shaking nystagmus (author’s transl)", Arch Otorhinolaryngol, 209(1), pp.59~67 (1975)
- Takahashi S, "Clinical significance of biphasic head-shaking nystagmus", Auris Nasus Larynx, 13(Suppl 2), pp.S199~204 (1986)
- Humphriss RL, "Head-shaking nystagmus in patients with a vestibular schwannoma", Clin Otolaryngol Allied Sci, 28(6), pp.514~519 (2003)
- Asawavichiangianda S, "Significance of head-shaking nystagmus in the evaluation of the dizzy patient", Acta Otolaryngol Suppl, 119(540), pp.27~33 (1999)
- Wei D, "Head-shaking nystagmus : Associations with canal paresis and hearing loss", Acta Otolaryngol, 108(5-6), pp.362~367 (1989)
- Jacobson GP, "Sensitivity and specificity of the head-shaking test for detecting vestibular system abnormalities", Ann Otol Rhinol Laryngol, 99(7 Pt 1), pp.539~542 (1990)
- Takahashi S, "The clinical significance of head-shaking nystagmus in the dizzy patient", Acta Otolaryngol, 109(1-2), pp.8~14 (1990)
- Hall SF, "Is head-shaking nystagmus a sign of vestibular dysfunction?", J Otolaryngol, 21(3), pp.209~212 (1992)
- Fujimoto M, "A study into the phenomenon of headshaking nystagmus : Its presence in a dizzy population", J Otolaryngol, 22(5), pp.376~379 (1993)
- Büttner U, "Gaze-evoked nystagmus and smooth pursuit deficits : Their relationship studied in 52 patients", J Neurol, 242(6), pp.384~389 (1995)
- Yetiser S, "Optokinetic analysis in patients with spontaneous horizontal gaze-evoked nystagmus without radiological neuropathology", Ear Nose Throat J, 98(7), pp.420~424 (2019)
- Pierrot-Deseilligny C, "Vertical nystagmus : Clinical facts and hypotheses", Brain, 128(Pt 6), pp.1237~1246 (2005)
- Strupp M, "Central ocular motor disorders, including gaze palsy and nystagmus", J Neurol, 261(Suppl 2), pp.S542~58 (2014)
- Rim HS, "Association of metabolic syndrome with sensorineural hearing loss", J Clin Med, 10(21), pp.4866~ (2021)
- 김진숙, "Test-Retest Reliability of Word Recognition Score Using Korean Standard Monosyllabic Word Lists for Adults as a Function of the Number of Test Words", Journal of Audiology & Otology, 19(2), pp.68~73 (2015), 대한청각학회
- Kim MB, "Diversity of head shaking nystagmus in peripheral vestibular disease", Otol Neurotol, 33(4), pp.634~639 (2012)
- Roosli C, "What is the site of origin of cochleovestibular schwannomas?", Audiol Neurootol, 17(2), pp.121~125 (2012)
- Komatsuzaki A, "Nerve origin of the acoustic neuroma", J Laryngol Otol, 115(5), pp.376~379 (2001)
- Saliba I, "Asymmetric hearing loss: Rule 3,000 for screening vestibular schwannoma", Otol Neurotol, 30(4), pp.515~521 (2009)