외비에서 발생한 선암종 1예
A Case of Adenocarcinoma of the External Nose
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Adenocarcinoma occurs very rarely in the paranasal sinuses; moreover, adenocarcinoma di-agnosed in the external nose is rarely reported. A 58-year-old male patient visited our hospitalwith an enlarged right nasal mass. On image studies, a 1.5 cm sized mass was found on theright nasolabial fold, which was surgically removed via sublabial approach. Intraoperative fro-zen section examination showed inflammatory tissue without tumor cells. However, adeno-carcinoma showing infiltration between the skeletal muscle layers was diagnosed on the finalhistopathologic examination after surgery. In the immunohistochemical staining test, CK7positive, CK20 negative, and GCDFP-15 positive were confirmed, so metastasis of adenocar-cinoma was considered first rather than primary cancer of the nasolabial fold. There was norecurrence and no tumor development in other sites after postoperative chemoradiation thera-py of 32 months.
Abstract
Adenocarcinoma occurs very rarely in the paranasal sinuses; moreover, adenocarcinoma di-agnosed in the external nose is rarely reported. A 58-year-old male patient visited our hospitalwith an enlarged right nasal mass. On image studies, a 1.5 cm sized mass was found on theright nasolabial fold, which was surgically removed via sublabial approach. Intraoperative fro-zen section examination showed inflammatory tissue without tumor cells. However, adeno-carcinoma showing infiltration between the skeletal muscle layers was diagnosed on the finalhistopathologic examination after surgery. In the immunohistochemical staining test, CK7positive, CK20 negative, and GCDFP-15 positive were confirmed, so metastasis of adenocar-cinoma was considered first rather than primary cancer of the nasolabial fold. There was norecurrence and no tumor development in other sites after postoperative chemoradiation thera-py of 32 months.
참고문헌 (10)
- Li X, "Risk factors and predictors for tumor site origin in metastatic adenocarcinoma of unknown primary site", Cancer Med, 10(3), pp.974~988 (2021)
- Kim S, "A case of metastatic rectal carcinoma to the frontal sinus", Korean J Otorhinolaryngol-Head Neck Surg, 60(6), pp.314~317 (2016)
- Batson OV, "The function of the vertebral veins and their role in the spread of metastases", Ann Surg, 112(1), pp.138~149 (1940)
- Haerle SK, "Sinonasal carcinomas: Epidemiology, pathology, and management", Neurosurg Clin N Am, 24(1), pp.39~49 (2013)
- Lund VJ, "Evidence for treatment strategies in sinonasal adenocarcinoma", Head Neck, 34(8), pp.1168~1178 (2012)
- Jankowski R, "Endoscopic surgery reveals that woodworkers’adenocarcinomas originate in the olfactory cleft", Rhinology, 45(4), pp.308~314 (2007)
- Leivo I, "Update on sinonasal adenocarcinoma : Classification and advances in immunophenotype and molecular genetic make-up", Head Neck Pathol, 1(1), pp.38~43 (2007)
- Ota I, "Cancer of unknown primary in the head and neck : Diagnosis and treatment", Auris Nasus Larynx, 48(1), pp.23~31 (2021)
- Jardeleza C, "Surgical outcomes of endoscopic management of adenocarcinoma of the sinonasal cavity", Rhinology, 47(4), pp.354~361 (2009)
- Leivo I, "Sinonasal adenocarcinoma: Update on classification, immunophenotype and molecular features", Head Neck Pathol, 10(1), pp.68~74 (2016)