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임상 증상에 따라 서로 다른 치료 방법을 선택한 미로내 신경초종 2예

2 Cases of Intra-Labyrinthine Schw annomas With Different Treatment Options Based on Clinical Presentation

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초록

Vestibular schwannoma is a benign tumor that arises from the eighth cranial nerve and is themost common neoplasm in the internal auditory canal (IAC). It typically arises in the cerebel-lopontine angle or in IAC; however, in rare cases, they can arise within the labyrinth. Thesetumors arising in the labyrinth have been termed intra-labyrinthine schwannomas (ILS) andhave different clinical features than the typical vestibular schwannomas. Clinical manifesta-tions of an ILS typically include hearing loss, tinnitus, and vertigo, with unusual symptomsincluding a sense of fullness or imbalance. Temporal bone MRI is considered the most impor-tant test for diagnosing ILS. Tumors show nodular enhancement on T1-weighted images andfilling defects on T2-weighted images. Treatment of ILS may include observation, microsurgi-cal resection, and stereotactic radiosurgery depending on the location, size, and clinical pre-sentation. In this paper, we present two cases diagnosed as ILS with different treatment op-tions and provide a literature review for each case.

Abstract

Vestibular schwannoma is a benign tumor that arises from the eighth cranial nerve and is themost common neoplasm in the internal auditory canal (IAC). It typically arises in the cerebel-lopontine angle or in IAC; however, in rare cases, they can arise within the labyrinth. Thesetumors arising in the labyrinth have been termed intra-labyrinthine schwannomas (ILS) andhave different clinical features than the typical vestibular schwannomas. Clinical manifesta-tions of an ILS typically include hearing loss, tinnitus, and vertigo, with unusual symptomsincluding a sense of fullness or imbalance. Temporal bone MRI is considered the most impor-tant test for diagnosing ILS. Tumors show nodular enhancement on T1-weighted images andfilling defects on T2-weighted images. Treatment of ILS may include observation, microsurgi-cal resection, and stereotactic radiosurgery depending on the location, size, and clinical pre-sentation. In this paper, we present two cases diagnosed as ILS with different treatment op-tions and provide a literature review for each case.

참고문헌 (10)

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  2. Wolf JS, "Imaging quiz case 2. Intralabyrinthine schwannoma", Arch Otolaryngol Head Neck Surg, 125(1), pp.107~109 (1999)
  3. Kennedy RJ, "Intralabyrinthine schwannomas: Diagnosis, management, and a new classification system", Otol Neurotol, 25(2), pp.160~167 (2004)
  4. Neff BA, "Intralabyrinthine schwannomas", Otol Neurotol, 24(2), pp.299~307 (2003)
  5. Kronenberg J, "Intracochlear schwannoma and cochlear implantation", Ann Otol Rhinol Laryngol, 108(7 Pt 1), pp.659~660 (1999)
  6. Salzman KL, "Intralabyrinthine schwannomas : Imaging diagnosis and classification", AJNR Am J Neuroradiol, 33(1), pp.104~109 (2012)
  7. Falcioni M, "Inner ear extension of vestibular schwannomas", Laryngoscope, 113(9), pp.1605~1608 (2003)
  8. Doyle KJ, "Intralabyrinthine schwannomas", Otolaryngol Head Neck Surg, 110(6), pp.517~523 (1994)
  9. Frisch CD, "Intralabyrinthine schwannomas", Otolaryngol Clin North Am, 48(3), pp.423~441 (2015)
  10. Di Lullo AM, "Diagnosis and management of intralabyrinthine schwannoma : Case series and review of the literature", Acta Biomed, 91(8-S), pp.136~144 (2020)

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