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Giant solitary pancreatic stone in a chronic pancreatitis patient

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Chronic pancreatitis (CP) is a chronic, progressive, inflammatory disease of the pancreas. Pancreatolithiasis is a complication of CP. In this case report, we present a patient with a giant solitary pancreatic stone that necessitated surgery. A 34-year-old patient with CP presented to our outpatient clinic with abdominal pain. Computed tomography revealed near-total atrophy of the pancreatic parenchyma and an 85-mm-long stone within the main pancreatic duct. Due to abdominal pain refractory to medical treatment and the long-term malignancy risk in the near-totally atrophic pancreas, the decision was made to perform surgery based on a multidisciplinary team meeting. Total pancreatectomy was carried out and a 30 × 85 mm pancreatic stone filling the main pancreatic duct was found in the specimen. Intractable pain, local complications of adjacent organs, and suspicion of a malignant lesion are indications for surgery in patients with CP. A case-based clinical approach is necessary for the management of pancreatic stones.

Abstract

Chronic pancreatitis (CP) is a chronic, progressive, inflammatory disease of the pancreas. Pancreatolithiasis is a complication of CP. In this case report, we present a patient with a giant solitary pancreatic stone that necessitated surgery. A 34-year-old patient with CP presented to our outpatient clinic with abdominal pain. Computed tomography revealed near-total atrophy of the pancreatic parenchyma and an 85-mm-long stone within the main pancreatic duct. Due to abdominal pain refractory to medical treatment and the long-term malignancy risk in the near-totally atrophic pancreas, the decision was made to perform surgery based on a multidisciplinary team meeting. Total pancreatectomy was carried out and a 30 × 85 mm pancreatic stone filling the main pancreatic duct was found in the specimen. Intractable pain, local complications of adjacent organs, and suspicion of a malignant lesion are indications for surgery in patients with CP. A case-based clinical approach is necessary for the management of pancreatic stones.

참고문헌 (5)

  1. van Huijgevoort NCM, "Success of extracorporeal shock wave lithotripsy and ERCP in symptomatic pancreatic duct stones : a systematic review and meta-analysis", Endosc Int Open, 8, pp.E1070~E1085 (2020)
  2. Sharzehi K, "Management of pancreatic duct stones", Curr Gastroenterol Rep, 21, pp.63~ (2019)
  3. Cahen DL, "Endoscopic versus surgical drainage of the pancreatic duct in chronic pancreatitis", N Engl J Med, 356, pp.676~684 (2007)
  4. Kirkegård J, "Chronic pancreatitis and pancreatic cancer risk : a systematic review and meta-analysis", Am J Gastroenterol, 112, pp.1366~1372 (2017)
  5. Kempeneers MA, "International consensus guidelines for surgery and the timing of intervention in chronic pancreatitis", Pancreatology, 20, pp.149~157 (2020)

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