A Case of Salivary-Type Amylase-Producing Multiple Myeloma Presenting as Mediastinal Plasmacytoma and Myelomatous Pleural Effusion
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Dear Editor Plasmacytoma, a neoplastic proliferation of plasma cells, is a type of plasma cell dyscrasia that may manifest as multiple my- eloma, primary amyloidosis, or monoclonal gammopathy of un- known significance. Extramedullary plasmacytoma rarely in- volves the mediastinum [1]. Simultaneous detection of mediasti- nal plasmacytoma and myelomatous pleural effusion accompa- nying myeloma is very rare. Furthermore, an amylase-producing multiple myeloma appears to be a fairly unusual phenomenon. This is a rare case of simultaneous extramedullary plasmacy- toma and myelomatous pleural effusion with increased salivary- type amylase levels without evidence of pancreatic or salivary gland involvement. This is the first reported case of mediastinal plasmacytoma and myelomatous pleural effusion as an initial presentation accompanying a salivary-type amylase-producing multiple myeloma in Korea.
Abstract
Dear Editor Plasmacytoma, a neoplastic proliferation of plasma cells, is a type of plasma cell dyscrasia that may manifest as multiple my- eloma, primary amyloidosis, or monoclonal gammopathy of un- known significance. Extramedullary plasmacytoma rarely in- volves the mediastinum [1]. Simultaneous detection of mediasti- nal plasmacytoma and myelomatous pleural effusion accompa- nying myeloma is very rare. Furthermore, an amylase-producing multiple myeloma appears to be a fairly unusual phenomenon. This is a rare case of simultaneous extramedullary plasmacy- toma and myelomatous pleural effusion with increased salivary- type amylase levels without evidence of pancreatic or salivary gland involvement. This is the first reported case of mediastinal plasmacytoma and myelomatous pleural effusion as an initial presentation accompanying a salivary-type amylase-producing multiple myeloma in Korea.
참고문헌 (7)
- Masood A, "Mediastinal plasmacytoma with multiple myeloma presenting as a diagnostic dilemma", Cases J, 1, pp.116~ (2008)
- Varettoni M, "Incidence, presenting features and outcome of extramedullary disease in multiple myeloma: a longitudinal study on 1003 consecutive patients", Ann Oncol, 21, pp.325~330 (2010)
- Delannoy A, "Amylase-producing IgD-type multiple myeloma", J Intern Med, 232, pp.457~460 (1992)
- Ohtsuki T, "Two human myeloma cell lines, amylase-producing KMS-12-PE and amylase-non-producing KMS-12-BM, were established from a patient, having the same chromosome marker, t(11;14)(q13;q32)", Br J Haematol, 73, pp.199~204 (1989)
- Lai JL, "Improved cytogenetics in multiple myeloma: a study of 151 patients including 117 patients at diagnosis", Blood, 85, pp.2490~2497 (1995)
- Sawyer JR, "Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin", Blood, 91, pp.1732~1741 (1998)
- Pinelli M, "Amylase: a disease activity index in multiple myeloma?", Leuk Lymphoma, 47, pp.151~154 (2006)