Prevalence of Schistosomes and Soil-Transmitted Helminths among Schoolchildren in Lake Victoria Basin, Tanzania
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The objectives of this study was to conduct a survey on schistosomiasis and soil-transmitted helminth (STH) infections in order to come up with feasible control strategies in Lake Victoria basin, Tanzania. Depending on the size of the school, 150-200 schoolchildren were recruited for the study. Duplicate Kato-Katz stool smears were prepared from each child and microscopically examined for Schistosoma mansoni and STHs. Urine specimens were examined for Schistosoma haematobium eggs using the filtration technique. After the survey, mass drug administration was done using praziquantel and albendazole for schistosomiasis and STHs infections, respectively. A total of 5,952 schoolchildren from 36 schools were recruited for the study and had their stool and urine specimens examined. Out of 5,952 schoolchildren, 898 (15.1%) were positive for S. mansoni, 754 (12.6%) for hookworms, 188 (3.2%) for Ascaris lumblicoides, and 5 (0.008%) for Trichuris trichiura. Out of 5,826 schoolchildren who provided urine samples, 519 (8.9%) were positive for S. haematobium eggs. The results revealed that intestinal schistosomiasis, urogenital schistosomiasis, and STH infections are highly prevalent throughought the lake basin. The high prevalence of intestinal and urogenital schistosomisiasis in the study area was a function of the distance from Lake Victoria, the former being more prevalent at localities close to the lake, whilst the latter is more so away from it. Control of schistosomiasis and STHs in the study area requires an integrated strategy that involves provision of health education to communities, regular treatments, and provision of adequate safe water supply and sanitation facilities.
Abstract
The objectives of this study was to conduct a survey on schistosomiasis and soil-transmitted helminth (STH) infections in order to come up with feasible control strategies in Lake Victoria basin, Tanzania. Depending on the size of the school, 150-200 schoolchildren were recruited for the study. Duplicate Kato-Katz stool smears were prepared from each child and microscopically examined for Schistosoma mansoni and STHs. Urine specimens were examined for Schistosoma haematobium eggs using the filtration technique. After the survey, mass drug administration was done using praziquantel and albendazole for schistosomiasis and STHs infections, respectively. A total of 5,952 schoolchildren from 36 schools were recruited for the study and had their stool and urine specimens examined. Out of 5,952 schoolchildren, 898 (15.1%) were positive for S. mansoni, 754 (12.6%) for hookworms, 188 (3.2%) for Ascaris lumblicoides, and 5 (0.008%) for Trichuris trichiura. Out of 5,826 schoolchildren who provided urine samples, 519 (8.9%) were positive for S. haematobium eggs. The results revealed that intestinal schistosomiasis, urogenital schistosomiasis, and STH infections are highly prevalent throughought the lake basin. The high prevalence of intestinal and urogenital schistosomisiasis in the study area was a function of the distance from Lake Victoria, the former being more prevalent at localities close to the lake, whilst the latter is more so away from it. Control of schistosomiasis and STHs in the study area requires an integrated strategy that involves provision of health education to communities, regular treatments, and provision of adequate safe water supply and sanitation facilities.
참고문헌 (58)
- World Health Organization, "Schistosomiasis: population requiring preventive chemotherapy and number of people treated in 2010", Weekly Epidemiol Rec, 87, pp.37~44 (2012)
- Steinmann P, "Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk", Lancet Infect Dis, 6, pp.411~425 (2006)
- "Special Programme for Research and Training in Tropical Diseases (TDR)"[URL]
- Crompton DWT, "Controlling disease due to helminth infection" (2003), World Health Organization
- Chitsulo L, "The global status of schistosomiasis and its control", Acta Trop, 77, pp.41~51 (2000)
- Mazigo HD, "Epidemiology and control of human schistosomiasis in Tanzania", Parasit Vectors, 5, pp.274~ (2012)
- Morgan JAT, "Schistosoma mansoni and Biomphalaria: past history and future trends", Parasitology, 123, pp.S211~S228 (2001)
- Stothard JR, "Use of circulating cathodic antigen (CCA) dipsticks for detection of intestinal and urinary schistosomiasis", Acta Trop, 97, pp.219~228 (2006)
- Standley CJ, "Intestinal schistosomiasis and soil-transmitted helminthiasis in Ugandan schoolchildren: a rapid mapping assessment", Geospat Health, 4, pp.39~53 (2009)
- Lwambo NJ, "Patterns of concurrent hookworm infection and schistosomiasis in schoolchildren in Tanzania", Trans R Soc Trop Med Hyg, 93, pp.497~502 (1999)
- Kinung’hi SM, "The impact of anthelmintic treatment intervention on malaria infection and anaemia in school and preschool children in Magu district, Tanzania: an open label randomised intervention trial", BMC Infect Dis, 15, pp.136~ (2015)
- Brooker S, "Rapid mapping of schistosomiasis and other neglected tropical diseases in the context of integrated control programmes in Africa", Parasitology, 136, pp.1707~1718 (2009)
- Verani JR, "Schistosomiasis among young children in Usoma, Kenya", Am J Trop Med Hyg, 84, pp.787~791 (2011)
- Odogwu SE, "Schistosoma mansoni in infants (aged <3 years) along the Ugandan shoreline of Lake Victoria", Ann Trop Med Parasitol, 100, pp.315~326 (2006)
- Stothard JR, "Field evaluation of the Meade Readiview handheld microscope for diagnosis of intestinal schistosomiasis in Ugandan school children", Am J Trop Med Hyg, 73, pp.949~955 (2005)
- Smith JH, "The pathobiology of Schistosoma haematobium infection in humans", Hum Pathol, 17, pp.333~345 (1986)
- Warren KS, "The pathology, pathobiology and pathogenesis of schistosomiasis", Nature, 273, pp.609~612 (1978)
- King CH, "Reassessment of the cost of chronic helmintic infection: a meta-analysis of disability-related outcomes in endemic schistosomiasis", Lancet, 365, pp.1561~1569 (2005)
- Jukes MC, "Heavy schistosomiasis associated with poor short-term memory and slower reaction times in Tanzanian schoolchildren", Trop Med Int Health, 7, pp.104~117 (2002)
- Ndamba J, "The physical fitness and work performance of agricultural workers infected with Schistosoma mansoni in Zimbabwe", Ann Trop Med Parasitol, 87, pp.553~561 (1993)
- Collins KJ, "Physiological performance and work capacity of Sudanese cane cutters with Schistosoma mansoni infection", Am J Trop Med Hyg, 25, pp.410~421 (1976)
- Fenwick A, "The effect of Schistosoma mansoni infection of the productivity of cane cutters on a sugar estate in Tanzania", Bull World Health Organ, 47, pp.567~572 (1972)
- Guidelines for the evaluation of soil-transmitted helminthiasis and schistosomiasis at community level, "Montresor A", World Health Organization, ~, pp.WHO (1998), CTD[DOI]
- Brooker S, "Global epidemiology, ecology and control of soil-transmitted helminth infection", Adv Parasitol, 62, pp.221~261 (2006)
- Hotez PJ, "Escalating the global fight against neglected tropical diseases through interventions in the Asia Pacific region", Adv Parasitol, 72, pp.31~53 (2010)
- Soil-transmitted helminthiases. Eliminating soil-transmitted helminthiases as a public health problem in children. Progress report 2001-2010 and strategic plan 2011-2020, "World Health Organization", World Health Organisation, ~ (2012)
- Hotez PJ, "Rescuing the bottom billion through control of neglected tropical diseases", Lancet, 373, pp.1570~1575 (2009)
- Ajanga A, "Schistosoma mansoni in pregnancy and associations with anaemia in northwest, Tanzania", Trans R Soc Trop Med Hyg, 100, pp.59~63 (2006)
- Brooker S, "Epidemiology of single and multiple species of helminth infections among school children in Busia District, Kenya", East Afr Med J, 77, pp.157~161 (2000)
- Clements AC, "Spatial co-distribution of neglected tropical diseases in the east African great lakes region: revisiting the justification for integrated control", Trop Med Int Health, 15, pp.198~207 (2010)
- Handzel T, "Geographic distribution of schistosomiasis and soil-transmitted helminths in Western Kenya: implication for anthelminthic mass treatment", Am J Trop Med Hyg, 69, pp.318~323 (2003)
- Nasr NA, "Towards an effective control programme of soil-transmitted helminth infections among Orang Asli in rural Malaysia. Part 1: prevalence and associated key factors", Parasit Vectors, 6, pp.27~ (2013)
- Brooker S, "Manson's Tropical Diseases", pp.848~853 (2008), Elsevier
- Hotez PJ, "Disease Control Priorities in Developing Countries", pp.467~497 (2006), Oxford University Press
- Keiser J, "Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis", JAMA, 299, pp.1937~1948 (2008)
- Taylor-Robinson DC, "Deworming drugs for treating soil-transmitted intestinal worms in children: effects on growth and school performance", Cochrane Database Syst Rev, (4), pp.CD000371~ (2007)
- Crompton DW, "Nutritional impact of intestinal helminthiasis during the human life cycle", Ann Rev Nutr, 22, pp.35~59 (2002)
- Hotez PJ, "Hookworm infection", N Engl J Med, 351, pp.799~807 (2004)
- Doenhoff MJ, "Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis", Curr Opin Infect Dis, 21, pp.659~667 (2008)
- Fleming FM, "Process evaluation of schistosomiasis control in Uganda, 2003 to 2006: perceptions, attitudes and constraints of a national programme", Parasitology, 136, pp.1759~1969 (2009)
- Hotez PJ, "Disease Control Priorities in Developing Countries" (2006), World Bank
- Kamel M, "Impact of type and stage of schistosomiasis on quality of life and productivity of infected workers", J Egypt Soc Parasitol, 3, pp.153~167 (2001)
- Conteh L, "Socioeconomic aspects of neglected tropical diseases", Lancet, 375, pp.239~247 (2010)
- Molyneux DH, "Neglected tropical diseases and the millennium development goals: why the 'other diseases' matter: reality versus rhetoric", Parasit Vectors, 4, pp.234~ (2011)
- Fincham JE, "Could control of soil-transmitted helminthic infection influence the HIV", AIDS pandemic, 2003, pp.86, 315~333
- Druilhe P, "Worms can worsen malaria: towards a new means to roll back malaria?", Trends Parasitol, 21, pp.359~362 (2005)
- Hotez PJ, "Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV", AIDS, tuberculosis, and malaria, 2006, pp.3, e102~
- Katz N, "A simple device for quantitative stool thick-smear technique in schistosomiasis mansoni", Rev Inst Med Trop Sao Paulo, 14, pp.397~400 (1972)
- Prevention and control of schistosomiasis and soil-transmitted helminthiasis: report of a WHO expert committee, "World Health Organization", World Health Organization, ~ (2001)
- Mazigo HD, "Co-infections with Plasmodium falciparum, Schistosoma mansoni and intestinal helminths among schoolchildren in endemic areas of northwestern Tanzania", Parasit Vectors, 3, pp.44~ (2010)
- Jordan P, "Schistosomiasis, Epidemiology, Treatment and Control", pp.227~229 (1982), Heinemann Medical Books
- Magendantz M, "The biology of Biomphalaria choanomphala and B. sudanica in relation to their role in the transmission of Schistosoma mansoni in Lake Victoria at Mwanza, Tanzania", Bull World Health Organ, 47, pp.331~342 (1972)
- Marti HP, "Studies on the ecology of Bulinus globosus, the intermediate host of Schistosoma haematobium, the Ifakara area, Tanzania", Acta Trop, 42, pp.171~187 (1985)
- Mwinzi PN, "Integrated community-directed intervention for schistosomiasis and soil transmitted helminths in western Kenya-a pilot study", Parasit Vectors, 5, pp.182~ (2012)
- Kariuki HC, "Distribution patterns and cercarial shedding of Bulinus nasutus and other snails in the Msambweni area, Coast Province, Kenya", Am J Trop Med Hyg, 70, pp.449~456 (2004)
- Brooker S, "Mapping soil-transmitted helminths in Southeast Asia and implications for parasite control", Southeast Asian J Trop Med Public Health, 34, pp.24~36 (2003)
- Appleton CC, "The distribution of common intestinal nematodes along an altitudinal transect in KwaZulu-Natal, South Africa", Ann Trop Med Parasitol, 90, pp.181~188 (1996)
- Kabatereine NB, "Impact of a national helminth control programme on infection and morbidity in Ugandan schoolchildren", Bull World Health Organ, 85, pp.91~99 (2007)