Late-onset Quetiapine-related Tardive Dyskinesia Side Effects in a Patient with Psychotic Depression
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The atypical antipsychotics were believed to induce less extrapyramidal syndrome, including tardive dyskinesia (TD). Since theintroduction of the quetiapine, it is also reported with less TD side effects. It even can relieve the symptoms of severe TD andreduce the risk of TD. The quetiapine’s low affinity and fast dissociation from postsynaptic dopamine D2 receptors should givethe least risk of producing the symptoms of TD. The quetiapine even can reduce the TD side effects related to clozapine, whichhas the lowest risk for TD. However, since the first case report of TD side effects related to quetiapine published on 1999,the safety of quetiapine in TD aspect has been questioned. Therefore, we want to share this case report, which was writtento describe the severe late-onset TD side effects after long-term use of quetiapine in a patient with psychotic depression. Thepatient had no significant findings after concurrent comprehensive neurological examinations, magnetic resonance imaging ofbrain and electroencephalogram since the onset of TD.
Abstract
The atypical antipsychotics were believed to induce less extrapyramidal syndrome, including tardive dyskinesia (TD). Since theintroduction of the quetiapine, it is also reported with less TD side effects. It even can relieve the symptoms of severe TD andreduce the risk of TD. The quetiapine’s low affinity and fast dissociation from postsynaptic dopamine D2 receptors should givethe least risk of producing the symptoms of TD. The quetiapine even can reduce the TD side effects related to clozapine, whichhas the lowest risk for TD. However, since the first case report of TD side effects related to quetiapine published on 1999,the safety of quetiapine in TD aspect has been questioned. Therefore, we want to share this case report, which was writtento describe the severe late-onset TD side effects after long-term use of quetiapine in a patient with psychotic depression. Thepatient had no significant findings after concurrent comprehensive neurological examinations, magnetic resonance imaging ofbrain and electroencephalogram since the onset of TD.
참고문헌 (19)
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