Recurrent Psychosis after Phentermine Administration in a Young Female: A Case Report
2
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
Phentermine is a sympathomimetic amine, like amphetamine, which is one of the most often prescribed drugs for weight loss. Although exact mechanism of phentermine causing psychosis is still not clear, numerous reports already showed that phentermine can induce psychosis. Psychotic symptoms are generally resolved once the medications are stopped. In contrast, we present a case of a 25-years-old Asian female patient who developed psychotic symptoms repeatedly after phentermine administrations. This case suggests that phentermine can cause psychotic episodes repeatedly, resulting in chronic occupational and social impairment. Therefore, a precautious measure such as government regulations for physicians prescribing and an education for patients taking phentermine are urgently needed.
Abstract
Phentermine is a sympathomimetic amine, like amphetamine, which is one of the most often prescribed drugs for weight loss. Although exact mechanism of phentermine causing psychosis is still not clear, numerous reports already showed that phentermine can induce psychosis. Psychotic symptoms are generally resolved once the medications are stopped. In contrast, we present a case of a 25-years-old Asian female patient who developed psychotic symptoms repeatedly after phentermine administrations. This case suggests that phentermine can cause psychotic episodes repeatedly, resulting in chronic occupational and social impairment. Therefore, a precautious measure such as government regulations for physicians prescribing and an education for patients taking phentermine are urgently needed.
참고문헌 (26)
- Korea Health Statistics 2014: Korea National Health and Nutrition Examination Survey (KNHANES VI-2), "Ministry of Health and Welfare", Korea Centers for Disease Control and Prevention, ~ (2015)
- Korean Society for the Study of Obesity, "Guideline for treatment of obesity 2012", Korean Society for the Study of Obesity, ~ (2012)
- 김경곤, "비만의 약물 요법", 대한의사협회지, 54(4), pp.409~418 (2011), 대한의사협회
- "Koreans overdose on diet pills" (2010)[URL]
- Daneschvar HL, "FDA-approved anti-obesity drugs in the United States", Am J Med, 129, pp.879.e1~879.e6 (2016)
- Bray GA, "Update on obesity pharmacotherapy", Ann N Y Acad Sci, 1311, pp.1~13 (2014)
- Bray GA, "A concise review on the therapeutics of obesity", Nutrition, 16, pp.953~960 (2000)
- 김경곤, "Effects on Weight Reduction and Safety of Short-Term Phentermine Administration in Korean Obese People", Yonsei Medical Journal, 47(5), pp.614~625 (2006), 연세대학교의과대학
- "Explanation materials of Yonhap News's coverage" (2016)[URL]
- Rubin RT, "Acute psychotic reaction following ingestion of phentermine", Am J Psychiatry, 120, pp.1124~1125 (1964)
- Shufman NE, "Ephedrine psychosis", Harefuah, 127, pp.166~168 (1994)
- Wang HR, "Caffeine-induced psychiatric manifestations : a review", Int Clin Psychopharmacol, 30, pp.179~182 (2015)
- Soon-Jai Kwon, "Appetite Suppressor Induced Psychosis", Clinical Psychopharmacology and Neuroscience, 8(3), pp.170~174 (2010), 대한정신약물학회
- Masakazu Hatano, "Assessment of the Latent Adverse Events of Antipsychotic Treatment Using a Subjective Questionnaire in Japanese Patients with Schizophrenia", Clinical Psychopharmacology and Neuroscience, 15(2), pp.132~137 (2017), 대한정신약물학회[DOI]
- Wolfgang Briegel, "Clinical Usefulness of Aripiprazole Treatment in a Girl with Prader-Willi Syndrome and Psychosis", Clinical Psychopharmacology and Neuroscience, 16(4), pp.497~500 (2018), 대한정신약물학회[DOI]
- Munro JF, "Comparison of continuous and intermittent anorectic therapy in obesity", Br Med J, 1, pp.352~354 (1968)
- Langlois KJ, "A double-blind clinical evaluation of the safety and efficacy of phentermine hydrochloride(Fastin)in the treatment of exogenous obesity", Curr Ther Res Clin Exp, 16, pp.289~296 (1974)
- Rothman RB, "Neurochemical mechanisms of phentermine and fenfluramine : therapeutic and adverse effects", Drug Dev Res, 51, pp.52~65 (2000)
- Ku JE, "Two cases of intoxication with phentermine", J Korean Soc Clin Toxicol, 12, pp.35~38 (2014)
- 안호영, "Phentermine, Sibutramine and Affective Disorders", Clinical Psychopharmacology and Neuroscience, 11(1), pp.7~12 (2013), 대한정신약물학회
- Devan GS, "Phentermine and psychosis", Br J Psychiatry, 156, pp.442~443 (1990)
- Alexander J, "Phentermine(Duromine)precipitated psychosis", Aust N Z J Psychiatry, 45, pp.684~685 (2011)
- Cleare AJ, "Phentermine, psychosis, and family history", J Clin Psychopharmacol, 16, pp.470~471 (1996)
- Hoffman BF, "Diet pill psychosis", Can Med Assoc J, 116, pp.351~355 (1977)
- Lee SH, "Schizophreniform-like psychotic disorder induced by phentermine: a case report", Zhonghua Yi Xue Za Zhi, 61, pp.44~47 (1998)
- National Law Information Ceter, Korea, "Enforcement rule of standard for medical care benefit of National Health Insurance, 2017", National Law Information Center, ~ (2017)