Patient Factors Influencing Outpatient Retention in Patients with Affective and Anxiety Disorders: A Retrospective Study
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective: The aim of the present study is to identify the factors that affect retention in outpatients with psychiatric disorders as indicators of treatment adherence, including Minnesota Multiphasic Personality Inventory (MMPI) scores. Methods: The medical records of 146 patients diagnosed with major depressive disorder, bipolar disorder, or anxiety disorder for at least 10 years and discharged were retrospectively reviewed in the present study. The subjects were categorized based on the duration of outpatient treatment as ＜ 6 months (L6) or ≥ 6 months (M6) groups and reclassified as ＜ 36 months (L36) and ≥ 36 months (M36) groups. The demographic, clinical, and personality characteristics of the groups were compared. Results: Patients in M6 and M36 groups were more likely to have a higher educational level compared with those in the L6 and L36 groups, respectively. Patients in the M6 group showed significantly lower hypomania (Ma) scores on the MMPI test than did patients in the L6 group. Conclusion: The association between high Ma score on the MMPI test and early discontinuation of treatment suggests that impulsivity, hostility, and disinhibition confer higher risk of nonadherence.
Abstract
Objective: The aim of the present study is to identify the factors that affect retention in outpatients with psychiatric disorders as indicators of treatment adherence, including Minnesota Multiphasic Personality Inventory (MMPI) scores. Methods: The medical records of 146 patients diagnosed with major depressive disorder, bipolar disorder, or anxiety disorder for at least 10 years and discharged were retrospectively reviewed in the present study. The subjects were categorized based on the duration of outpatient treatment as ＜ 6 months (L6) or ≥ 6 months (M6) groups and reclassified as ＜ 36 months (L36) and ≥ 36 months (M36) groups. The demographic, clinical, and personality characteristics of the groups were compared. Results: Patients in M6 and M36 groups were more likely to have a higher educational level compared with those in the L6 and L36 groups, respectively. Patients in the M6 group showed significantly lower hypomania (Ma) scores on the MMPI test than did patients in the L6 group. Conclusion: The association between high Ma score on the MMPI test and early discontinuation of treatment suggests that impulsivity, hostility, and disinhibition confer higher risk of nonadherence.
참고문헌 (44)
- Weiden PJ, "Understanding and addressing adherence issues in schizophrenia : from theory to practice", J Clin Psychiatry, 68(Suppl 14), pp.14~19 (2007)
- ten Doesschate MC, "Predictors of nonadherence to continuation and maintenance antidepressant medication in patients with remitted recurrent depression", J Clin Psychiatry, 70, pp.63~69 (2009)
- Chui E, "Validation study of the Brief Medication Adherence Scale(BMAS)in patients with schizophrenia and related disorders in Hong Kong", Asian J Psychiatr, 37, pp.154~160 (2018)
- Kaplan G, "Impact of long-acting injectable antipsychotics on medication adherence and clinical, functional, and economic outcomes of schizophrenia", Patient Prefer Adherence, 7, pp.1171~1180 (2013)
- Lingam R, "Treatment non-adherence in affective disorders", Acta Psychiatr Scand, 105, pp.164~172 (2002)
- Sajatovic M, "A 6-month, prospective, randomized controlled trial of customized adherence enhancement versus bipolar-specific educational control in poorly adherent individuals with bipolar disorder", J Clin Psychiatry, 79, pp.17~ (2018)
- Sajatovic M, "Treatment adherence with antipsychotic medications in bipolar disorder", Bipolar Disord, 8, pp.232~241 (2006)
- Keyloun KR, "Adherence and persistence across antidepressant therapeutic classes : a retrospective claims analysis among insured US patients with major depressive disorder(MDD)", CNS Drugs, 31, pp.421~432 (2017)
- Pompili M, "Mood disorders medications : predictors of nonadherence-review of the current literature", Expert Rev Neurother, 13, pp.809~825 (2013)
- Yujin Lee, "Medication Adherence Using Electronic Monitoring in Severe Psychiatric Illness: 4 and 24 Weeks after Discharge", Clinical Psychopharmacology and Neuroscience, 17(2), pp.288~296 (2019), 대한정신약물학회[DOI]
- 김종기, "Childhood Trauma and Treatment Implications in Major Depressive Disorder in South Korea: Comparison with Medical Outpatients and Two-Year Follow-Up", Mood and Emotion, 17(3), pp.89~98 (2019), 대한우울조울병학회
- Haddad PM, "Nonadherence with antipsychotic medication in schizophrenia : challenges and management strategies", Patient Relat Outcome Meas, 5, pp.43~62 (2014)
- Wiebe JS, "Patient adherence in chronic illness : personality and coping in context", J Pers, 64, pp.815~835 (1996)
- Jhin Goo Chang, "Association between Therapeutic Alliance and Adherence in Outpatient Schizophrenia Patients", Clinical Psychopharmacology and Neuroscience, 17(2), pp.273~278 (2019), 대한정신약물학회[DOI]
- Levak RW, "Therapeutic feedback with the MMPI-2: a positive psychology approach" (2011), Taylor & Francis Group
- Ren XS, "Measurement of treatment adherence with antipsychotic agents in patients with schizophrenia", Neuropsychiatr Dis Treat, 5, pp.491~498 (2009)
- Greevy RA Jr, "Comparisons of persistence and durability among three oral antidiabetic therapies using electronic prescription-fill data : the impact of adherence requirements and stockpiling", Clin Pharmacol Ther, 90, pp.813~819 (2011)
- Butcher JN, "Manual for the restandardized Minnesota Multiphasic Personality Inventory: MMPI-2. An administrative and interpretive guide" (1989), University of Minnesota Press
- Butcher JN, "MMPI-2: Minnesota Multiphasic Personality Inventory-2: manual for administration, scoring, and interpretation" (2001), University of Minnesota Press
- Post RD, "MMPI predictors of mania among psychiatric inpatients", J Pers Assess, 50, pp.248~256 (1986)
- Wetzler S, "The use of the MMPI-2 for the assessment of depressive and psychotic disorders", Assessment, 5, pp.249~261 (1998)
- Cohen NL, "The 5-factor model of personality and antidepressant medication compliance", Can J Psychiatry, 49, pp.106~113 (2004)
- Fleischhacker WW, "Factors influencing compliance in schizophrenia patients", J Clin Psychiatry, 64(Suppl 16), pp.10~13 (2003)
- Misdrahi D, "The influence of therapeutic alliance and insight on medication adherence in schizophrenia", Nord J Psychiatry, 66, pp.49~54 (2012)
- Dolder CR, "Interventions to improve antipsychotic medication adherence : review of recent literature", J Clin Psychopharmacol, 23, pp.389~399 (2003)
- Llorca PM, "Partial compliance in schizophrenia and the impact on patient outcomes", Psychiatry Res, 161, pp.235~247 (2008)
- Lacro JP, "Prevalence of and risk factors for medication nonadherence in patients with schizophrenia : a comprehensive review of recent literature", J Clin Psychiatry, 63, pp.892~909 (2002)
- Masakazu Hatano, "Satisfaction Survey on Antipsychotic Formulations by Schizophrenia Patients in Japan", Clinical Psychopharmacology and Neuroscience, 19(4), pp.610~617 (2021), 대한정신약물학회[DOI]
- Fiorillo A, "The role of shared decision-making in improving adherence to pharmacological treatments in patients with schizophrenia : a clinical review", Ann Gen Psychiatry, 19, pp.43~ (2020)
- Hiroyuki Kamei, "Effectiveness in Switching from Antipsychotic Polypharmacy to Monotherapy in Patients with Schizophrenia: A Case Series", Clinical Psychopharmacology and Neuroscience, 18(1), pp.159~163 (2020), 대한정신약물학회[DOI]
- Julius RJ, "Medication adherence : a review of the literature and implications for clinical practice", J Psychiatr Pract, 15, pp.34~44 (2009)
- 장현갑, "Factors Affecting Public Prejudice and Social Distance on Mental Illness: Analysis of Contextual Effect by Multi-level Analysis", 예방의학회지, 45(2), pp.90~97 (2012), 대한예방의학회
- Yuan Q, "Attitudes to mental illness and its demographic correlates among general population in Singapore", PLoS One, 11, pp.e0167297~ (2016)
- Velligan DI, "The expert consensus guideline series: adher-ence problems in patients with serious and persistent mental illness", J Clin Psychiatry, 70(Suppl 4), pp.1~46 (2009)
- Abdullah T, "Mental illness stigma and ethnocultural beliefs, values, and norms : an integrative review", Clin Psychol Rev, 31, pp.934~948 (2011)
- Corrigan P, "How stigma interferes with mental health care", Am Psychol, 59, pp.614~625 (2004)
- Rao D, "Racial and ethnic disparities in mental illness stigma", J Nerv Ment Dis, 195, pp.1020~1023 (2007)
- Lauber C, "Stigma towards people with mental illness in developing countries in Asia", Int Rev Psychiatry, 19, pp.157~178 (2007)
- Sanchez F, "Mental health care of Filipino Americans", Psychiatr Serv, 58, pp.810~815 (2007)
- Hou R, "Do treatment and illness beliefs influence adherence to medication in patients with bipolar affective disorder? A preliminary cross-sectional study", Eur Psychiatry, 25, pp.216~219 (2010)
- Barraco A, "Description of study population and analysis of factors influencing adherence in the observational Italian study"Evaluation of Pharmacotherapy Adherence in Bipolar Disorder"(EPHAR)", CNS Neurosci Ther, 18, pp.110~118 (2012)
- Zivin K, "Antidepressant adherence after psychiatric hospitalization among VA patients with depression", Adm Policy Ment Health, 36, pp.406~415 (2009)
- Sajatovic M, "Treatment adherence with lithium and anticonvulsant medications among patients with bipolar disorder", Psychiatr Serv, 58, pp.855~863 (2007)
- Roca M, "Adherence to medication in depressive patients", J Clin Psychopharmacol, 31, pp.541~543 (2011)