Reliability of the Korean Nottingham Onset Schedule (K-NOS) in Korean First-episode Psychosis Patients
1
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Objective：The duration of untreated psychosis (DUP) has been associated with patient treatment outcome. This study assessed the reliability of the Korean version of the Nottingham Onset Schedule (K-NOS) in assessing DUP among Korean first-episode psychosis patients. Methods：A total of 20 first-episode psychosis patients (mean age=27.1±9.7, range 17−51, males=11) participated in the study. Inter-rater reliability and test-retest reliability were assessed for all subjects using Kappa coefficients and intra-class correlation coefficient (ICC). Five duration criteria of untreated psychosis were determined. Results：The most common prodromal symptoms were irritability, poor mood, sleep changes, and the tendency to avoid people. The most common first psychotic symptoms were auditory hallucination and persecutory delusions. The duration of untreated illness was 332±342 weeks at the time of testing and 336±346 weeks at the time of retesting, and the duration of untreated manifest psychosis was 34±52 weeks at the time of testing and 34±52 weeks at the time of retesting. The duration of untreated emergent psychosis was 78±145 weeks at the time of testing and 77±145 weeks at the time of retesting. Inter-rater reliability of the NOS interview was statistically significant (P-DDx, ICC=0.992, p＜0.001; FPS-DDx, ICC=0.851, p＜0.001; P-T, ICC=0.996, p＜0.001; FBS-T, ICC=0.941, p＜0.001; DDx-T, ICC=0.888, p＜0.001). Test-retest reliability of the NOS interview was also very high (P-DDx, ICC=0.975, p＜0.001; FPS-DDx, ICC=1, p＜0.001; P-T, ICC=0.999, p＜0.001; FBS-T, ICC=0.999, p＜0.001; DDx-T, ICC=1, p＜0.001). Conclusions：The results of this study suggest that the Korean version of Nottingham Onset Schedule measures DUP among Korean first-episode psychosis patients with acceptable reliability.
Abstract
Objective：The duration of untreated psychosis (DUP) has been associated with patient treatment outcome. This study assessed the reliability of the Korean version of the Nottingham Onset Schedule (K-NOS) in assessing DUP among Korean first-episode psychosis patients. Methods：A total of 20 first-episode psychosis patients (mean age=27.1±9.7, range 17−51, males=11) participated in the study. Inter-rater reliability and test-retest reliability were assessed for all subjects using Kappa coefficients and intra-class correlation coefficient (ICC). Five duration criteria of untreated psychosis were determined. Results：The most common prodromal symptoms were irritability, poor mood, sleep changes, and the tendency to avoid people. The most common first psychotic symptoms were auditory hallucination and persecutory delusions. The duration of untreated illness was 332±342 weeks at the time of testing and 336±346 weeks at the time of retesting, and the duration of untreated manifest psychosis was 34±52 weeks at the time of testing and 34±52 weeks at the time of retesting. The duration of untreated emergent psychosis was 78±145 weeks at the time of testing and 77±145 weeks at the time of retesting. Inter-rater reliability of the NOS interview was statistically significant (P-DDx, ICC=0.992, p＜0.001; FPS-DDx, ICC=0.851, p＜0.001; P-T, ICC=0.996, p＜0.001; FBS-T, ICC=0.941, p＜0.001; DDx-T, ICC=0.888, p＜0.001). Test-retest reliability of the NOS interview was also very high (P-DDx, ICC=0.975, p＜0.001; FPS-DDx, ICC=1, p＜0.001; P-T, ICC=0.999, p＜0.001; FBS-T, ICC=0.999, p＜0.001; DDx-T, ICC=1, p＜0.001). Conclusions：The results of this study suggest that the Korean version of Nottingham Onset Schedule measures DUP among Korean first-episode psychosis patients with acceptable reliability.
참고문헌 (23)
- Kelly C, "Nithsdale schizophrenia surveys. 17. Fifteen-year review", Br J Psychiatry, 172, pp.513~517 (1998)
- Larsen TK, "First-episode schizophrenia with long duration of untreated psychosis. Pathways to care", Br J Psychiatry Suppl, 172, pp.45~52 (1998)
- Helgason L, "Twenty years' follow-up of first psychiatric presentation for schizophrenia: what could have been prevented?", Acta Psychiatr Scand, 81, pp.231~235 (1990)
- Johnstone EC, "The Northwick Park study of first episodes of schizophrenia. I. Presentation of the illness and problems relating to admission", Br J Psychiatry, 148, pp.115~120 (1986)
- Loebel AD, "Mayerhoff DI, GeislerSH, Szymanski SR. Duration of psychosis and outcome in first-episode schizophrenia", Am J Psychiatry, 149, pp.1183~1188 (1992)
- Barnes TR, "West London first-episode study of schizophrenia. Clinical correlates of duration of untreated psychosis", Br J Psychiatry, 177, pp.207~211 (2000)
- Ho BC, "Untreated initial psychosis: Its relation to quality of life and symptom remission in first-episode schizophrenia", Am J Psychiatry, 157, pp.808~815 (2000)
- Browne S, "Determinants of quality of life at first presentation with schizophrenia", Br J Psychiatry, 176, pp.173~176 (2000)
- Lincoln CV, "Who cares? Pathways to psychiatric care for young people experiencing a first episode of psychosis", Psychiatr Serv, 46, pp.1166~1171 (1995)
- Moscarelli M, "Cost evaluation of chronic schizophrenic patients during the first 3 years after the first contact", Schizophr Bull, 17, pp.421~426 (1991)
- Wyatt RJ, "Early intervention with neuroleptics may decrease the long-term morbidity of schizophrenia", Schizophr Res, 5, pp.201~202 (1991)
- Birchwood M, "Early intervention in schizophrenia", Aust N Z J Psychiatry, 27, pp.374~378 (1993)
- McGlashan TH, "Early detection and intervention in schizophrenia: editor's introduction", Schizophr Bull, 22, pp.197~199 (1996)
- Singh SP, "Determining the chronology and components of psychosis onset: the Nottingham Onset Schedule (NOS)", Schizophr Res, 80, pp.117~130 (2005)
- Joa I, "Baseline profiles of adolescent vs. adult-onset first-episode psychosis in an early detection program", Acta Psychiatr Scand, 119, pp.494~500 (2009)
- Yung AR, "prodromal phase of firstepisode psychosis: past and current conceptualizations", Schizophr Bull, 22, pp.353~370 (1996)
- Norman RM, "Duration of untreated psychosis: a critical examination of the concept and its importance", Psychol Med, 31, pp.381~400 (2001)
- Altamura AC, "Duration of untreated psychosis as a predictor of outcome in first-episode schizophrenia: a retrospective study", Schizophr Res, 52, pp.29~36 (2001)
- Norman RM, "Duration of untreated psychosis and its relationship to clinical outcome", Br J Psychiatry Suppl, 48, pp.s19~s23 (2005)
- Yung AR, "Prediction of psychosis. A step towards indicated prevention of schizophrenia", Br J Psychiatry Suppl, 172, pp.14~20 (1998)
- Linszen D, "Early intervention, untreated psychosis and the course of early schizophrenia", Br J Psychiatry Suppl, 172, pp.84~89 (1998)
- Szymanski SR, "Course of treatment response in first-episode and chronic schizophrenia", Am J Psychiatry, 153, pp.519~525 (1996)
- Barnes TR, "Duration of untreated psychosis and social function: 1-year follow-up study of first-episode schizophrenia", Br J Psychiatry, 193, pp.203~209 (2008)