본문 바로가기
KERD
논문KCI 등재

Targeting Three Brain Regions (Bilateral SMA, Left and Right DLPFC) Sequentially in One Session Using Combined Repetitive Transcranial Magnetic Stimulation and Intermittent Theta-burst Stimulation in Treatment-refractory Obsessive-compulsive Disorder: A Case Report

0

조회

0

다운로드

0

인용

0

참고문헌

키워드

초록

Repetitive transcranial magnetic stimulation (rTMS) has been widely used as a therapy for refractory obsessive-compulsive disorder (OCD). However, it remains unclear which exact target and stimulation sequence of rTMS is most effective for OCD. Here, we report the case of an 18-year-old female with treatment-refractory OCD whose symptoms markedly improved after combined rTMS and intermittent theta-burst stimulation over the bilateral dorsolateral prefrontal cortex and supplementary motor area. Our report indicates that combining treatment sequences that stimulate different brain regions sequentially is feasible and may clinically benefit patients suffering from OCD.

Abstract

Repetitive transcranial magnetic stimulation (rTMS) has been widely used as a therapy for refractory obsessive-compulsive disorder (OCD). However, it remains unclear which exact target and stimulation sequence of rTMS is most effective for OCD. Here, we report the case of an 18-year-old female with treatment-refractory OCD whose symptoms markedly improved after combined rTMS and intermittent theta-burst stimulation over the bilateral dorsolateral prefrontal cortex and supplementary motor area. Our report indicates that combining treatment sequences that stimulate different brain regions sequentially is feasible and may clinically benefit patients suffering from OCD.

참고문헌 (21)

  1. Ruscio AM, "The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication", Mol Psychiatry, 15, pp.53~63 (2010)
  2. Simpson HB, "Response versus remission in obsessive-compulsive disorder", J Clin Psychiatry, 67, pp.269~276 (2006)
  3. Liang K, "Efficacy and tolerability of repetitive transcranial magnetic stimulation for the treatment of obsessive-compulsive disorder in adults : a systematic review and network meta-analysis", Transl Psychiatry, 11, pp.332~ (2021)
  4. Naro A, "Theta burst stimulation for the treatment of obsessivecompulsive disorder: a pilot study", J Neural Transm(Vienna), 126, pp.1667~1677 (2019)
  5. Roth Y, "Real-world efficacy of deep TMS for obsessive-compulsive disorder : post-marketing data collected from twenty-two clinical sites", J Psychiatr Res, 137, pp.667~672 (2021)
  6. Carmi L, "Efficacy and safety of deep transcranial magnetic stimulation for obsessive-compulsive disorder : a prospective multicenter randomized double-blind placebo-controlled trial", Am J Psychiatry, 176, pp.931~938 (2019)
  7. 서호준, "Adjunctive Low-frequency Repetitive Transcranial Magnetic Stimulation over the Right Dorsolateral Prefrontal Cortex in Patients with Treatment-resistant Obsessive-compulsive Disorder: A Randomized Controlled Trial", Clinical Psychopharmacology and Neuroscience, 14(2), pp.153~160 (2016), 대한정신약물학회
  8. Mantovani A, "Randomized sham-controlled trial of repetitive transcranial magnetic stimulation in treatment-resistant obsessive-compulsive disorder", Int J Neuropsychopharmacol, 13, pp.217~227 (2010)
  9. Chou PH, "Antidepressant efficacy and immune effects of bilateral theta burst stimulation monotherapy in major depression : a randomized, double-blind, sham-controlled study", Brain Behav Immun, 88, pp.144~150 (2020)
  10. Mantovani A, "Repetitive transcranial magnetic stimulation(rTMS)in the treatment of obsessive-compulsive disorder(OCD)and Tourette’s syndrome(TS)", Int J Neuropsychopharmacol, 9, pp.95~100 (2006)
  11. Beam W, "An efficient and accurate new method for locating the F3 position for prefrontal TMS applications", Brain Stimul, 2, pp.50~54 (2009)
  12. Stein DJ, "Obsessive-compulsive disorder", Nat Rev Dis Primers, 5, pp.52~ (2019)
  13. Rehn S, "A meta-analysis of the effectiveness of different cortical targets used in repetitive transcranial magnetic stimulation(rTMS)for the treatment of obsessive-compulsive disorder(OCD)", Psychiatr Q, 89, pp.645~665 (2018)
  14. Aron AR, "Inhibition and the right inferior frontal cortex", Trends Cogn Sci, 8, pp.170~177 (2004)
  15. Picard N, "Imaging the premotor areas", Curr Opin Neurobiol, 11, pp.663~672 (2001)
  16. Miller EK, "An integrative theory of prefrontal cortex function", Annu Rev Neurosci, 24, pp.167~202 (2001)
  17. Zhou DD, "An updated meta-analysis : short-term therapeutic effects of repeated transcranial magnetic stimulation in treating obsessive-compulsive disorder", J Affect Disord, 215, pp.187~196 (2017)
  18. Menzies L, "Integrating evidence from neuroimaging and neuropsychological studies of obsessive-compulsive disorder : the orbitofronto-striatal model revisited", Neurosci Biobehav Rev, 32, pp.525~549 (2008)
  19. Blumberger DM, "Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression(THREE-D) : a randomised non-inferiority trial", Lancet, 391, pp.1683~1692 (2018)
  20. Haghighi M, "Repetitive Transcranial Magnetic Stimulation(rTMS)improves symptoms and reduces clinical illness in patients suffering from OCD--results from a singleblind, randomized clinical trial with sham cross-over condition", J Psychiatr Res, 68, pp.238~244 (2015)
  21. Po-Han Chou, "Personalization of Repetitive Transcranial Magnetic Stimulation for the Treatment of Major Depressive Disorder According to the Existing Psychiatric Comorbidity", Clinical Psychopharmacology and Neuroscience, 19(2), pp.190~205 (2021), 대한정신약물학회[DOI]

관련 논문AI추천

Adjunctive Low-frequency Repetitive Transcranial Magnetic Stimulation over the Right Dorsolateral Prefrontal Cortex in Patients with Treatment-resistant Obsessive-compulsive Disorder: A Randomized Controlled Trial서호준, 엄유현, 이창욱, 임현국, 정영은, 채정호대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2016 · 제14권 제2호A Case Series on the Effect of Continuous Theta Burst Stimulation over Supplementary Motor Cortex in Obsessive-compulsive DisorderAmit Singh, Babli Kumari, Mohita Joshi, Sujita Kumar Kar대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2025 · 제23권 제2호Personalization of Repetitive Transcranial Magnetic Stimulation for the Treatment of Major Depressive Disorder According to the Existing Psychiatric ComorbidityAlexander T. Sack, Che-Sheng Chu, Hsin-An Chang, Kuan-Pin Su, Ming-Kuei Lu, Po-Han Chou, Taishiro Kishimoto, Wei Hung Chang, Yen-Feng Lin대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2021 · 제19권 제2호New Onset Obsessive Compulsive Disorder Following High Frequency Repetitive Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex for Treatment of Negative Symptoms in a Patient with SchizophreniaHarshit Garg, Nand Kumar, Rohit Verma, Saurabh Kumar, Swarndeep Singh대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2019 · 제17권 제3호Safety and Efficacy of an Intensified and Repeated Transcranial Direct Current Stimulation Targeting Supplementary Motor Area and Dorsolateral Prefrontal Cortex in Trichotillomania (Hair Pulling Disorder): A Case ReportAsghar Pouresmali, Jaber Alizadehgoradel, Mina Taherifard대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2024 · 제22권 제1호Repetitive Transcranial Magnetic Stimulation for Treatment of Trichotillomania: Case SeriesAslı Tutan, Efruz Pirdoğan Aydın, Jülide Güler Kenar, Kayıhan Oğuz Karamustafalıoğlu, Ömer Akil Özer대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2020 · 제18권 제4호

이 간행물의 다른 논문 (19건)