Mirtazapine Monotherapy for Antipsychotics-refractory Psychosis in a Patient with Very-late-onset Schizophrenia-like Psychosis: A Case Report
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Very-late-onset schizophrenia-like psychosis (VLOSLP) is a condition in which psychotic symptoms emerge after the age of 60 years. Given its heterogeneous nature, VLOSLP remains a diagnostic and therapeutic dilemma. Here, we report a case of a 68-year-old patient with psychosis refractory to antipsychotics who was successfully treated with mirtazapine monotherapy. This case suggests that mirtazapine monotherapy may be effective for the treatment of patients with antipsychotic-refractory VLOSLP.
Abstract
Very-late-onset schizophrenia-like psychosis (VLOSLP) is a condition in which psychotic symptoms emerge after the age of 60 years. Given its heterogeneous nature, VLOSLP remains a diagnostic and therapeutic dilemma. Here, we report a case of a 68-year-old patient with psychosis refractory to antipsychotics who was successfully treated with mirtazapine monotherapy. This case suggests that mirtazapine monotherapy may be effective for the treatment of patients with antipsychotic-refractory VLOSLP.
참고문헌 (12)
- Howard R, "Late-onset schizophrenia and very-late-onset schizophrenia-like psychosis : an international consensus", Am J Psychiatry, 157, pp.172~178 (2000)
- Webster J, "Late-life onset of psychotic symptoms", Am J Geriatr Psychiatry, 6, pp.196~202 (1998)
- Fleisher AS, "Clinical predictors of progression to Alzheimer disease in amnestic mild cognitive impairment", Neurology, 68, pp.1588~1595 (2007)
- Bang J, "Frontotemporal dementia", Lancet, 386, pp.1672~1682 (2015)
- Collerton D, "Systematic review and meta-analysis show that dementia with Lewy bodies is a visual-perceptual and attentional-executive dementia", Dement Geriatr Cogn Disord, 16, pp.229~237 (2003)
- Kishi T, "Meta-analysis of noradrenergic and specific serotonergic antidepressant use in schizophrenia", Int J Neuropsychopharmacol, 17, pp.343~354 (2014)
- Cummings J, "Pimavanserin : potential treatment for dementia-related psychosis", J Prev Alzheimers Dis, 5, pp.253~258 (2018)
- Pose M, "The overlap of symptomatic dimensions between frontotemporal dementia and several psychiatric disorders that appear in late adulthood", Int Rev Psychiatry, 25, pp.159~167 (2013)
- Joffe G, "Add-on mirtazapine enhances antipsychotic effect of first generation antipsychotics in schizophrenia : a double-blind, randomized, placebo-controlled trial", Schizophr Res, 108, pp.245~251 (2009)
- Meco G, "Antidepressant use in treatment of psychosis with comorbid depression in Parkinson’s disease", Prog Neuropsychopharmacol Biol Psychiatry, 31, pp.311~313 (2007)
- Seitz DP, "Antidepressants for agitation and psychosis in dementia", Cochrane Database Syst Rev, (2), pp.CD008191~ (2011)
- de Boer T, "The pharmacologic profile of mirtazapine", J Clin Psychiatry, 57(Suppl 4), pp.19~25 (1996)
