본문 바로가기
KERD
논문KCI 등재

Prevalence and Comorbidities of Attention Deficit Hyperactivity Disorder Among Adults and Children/Adolescents in Korea

2

조회

0

다운로드

9

인용

0

참고문헌

키워드

초록

Objective: This study investigated the prevalence and comorbidities of attention deficit hyperactivity disorder (ADHD) among adults and children/adolescents in Korea. Methods: This study used data from the Korea Health Insurance Review and Assessment Service collected from 2008 to 2018. Study participants comprised patients with at least one diagnosis of ADHD (International Statistical Classification of Diseases and Related Health Provisions, 10th revision code F90.0). Prevalence rates and psychiatric comorbidities were also analyzed. Results: We identified 878,996 patients diagnosed with ADHD between 2008 and 2018. The overall prevalence rate of diagnosed ADHD increased steeply from 127.1/100,000 in 2008 to 192.9/100,000 in 2018; it increased 1.47 times in children/adolescents (≤ 18 years) and 10.1 times in adults (> 18 years) during this period. Among adult and children/ adolescent ADHD patients, 61.84% (95% confidence interval [95% CI] 61.74−61.93) and 78.72% (95% CI 78.53− 78.91) had at least one psychiatric comorbidity, respectively. Conclusion: Our results showed that the prevalence rate of diagnosed ADHD has increased in Korea; however, it is lower than the global average. Further studies are required to identify and treat vulnerable populations appropriately.

Abstract

Objective: This study investigated the prevalence and comorbidities of attention deficit hyperactivity disorder (ADHD) among adults and children/adolescents in Korea. Methods: This study used data from the Korea Health Insurance Review and Assessment Service collected from 2008 to 2018. Study participants comprised patients with at least one diagnosis of ADHD (International Statistical Classification of Diseases and Related Health Provisions, 10th revision code F90.0). Prevalence rates and psychiatric comorbidities were also analyzed. Results: We identified 878,996 patients diagnosed with ADHD between 2008 and 2018. The overall prevalence rate of diagnosed ADHD increased steeply from 127.1/100,000 in 2008 to 192.9/100,000 in 2018; it increased 1.47 times in children/adolescents (≤ 18 years) and 10.1 times in adults (> 18 years) during this period. Among adult and children/ adolescent ADHD patients, 61.84% (95% confidence interval [95% CI] 61.74−61.93) and 78.72% (95% CI 78.53− 78.91) had at least one psychiatric comorbidity, respectively. Conclusion: Our results showed that the prevalence rate of diagnosed ADHD has increased in Korea; however, it is lower than the global average. Further studies are required to identify and treat vulnerable populations appropriately.

참고문헌 (46)

  1. American Psychiatric Association, "Diagnostic and statistical manual of mental disorders: DSM-5" (2013), American Psychiatric Association
  2. Barkley RA, "The persistence of attention-deficit", hyperactivity disorder into young adulthood as a function of reporting source and definition of disorder, 2002, pp.111, 279~289
  3. Turgay A, "Lifespan persistence of ADHD : the life transition model and its application", J Clin Psychiatry, 73, pp.192~201 (2012)
  4. Trollor JN, "Attention deficit hyperactivity disorder in adults : conceptual and clinical issues", Med J Aust, 171, pp.421~425 (1999)
  5. Castellanos FX, "Is adult-onset ADHD a distinct entity?", Am J Psychiatry, 172, pp.929~931 (2015)
  6. Faraone SV, "Can attention-deficit", hyperactivity disorder onset occur in adulthood?, 2016, pp.73, 655~656
  7. Sibley MH, "Late-onset ADHD reconsidered with comprehensive repeated assessments between ages 10 and 25", Am J Psychiatry, 175, pp.140~149 (2018)
  8. Katzman MA, "Adult ADHD and comorbid disorders : clinical implications of a dimensional approach", BMC Psychiatry, 17, pp.302~ (2017)
  9. Chung W, "Trends in the prevalence and incidence of attention-deficit", hyperactivity disorder among adults and children of different racial and ethnic groups, 2019, pp.2, e1914344~
  10. Bruchmüller K, "ADHD diagnosed in accord with diagnostic criteria? Overdiagnosis and influence of client gender on diagnosis", J Consult Clin Psychol, 80, pp.128~138 (2012)
  11. Cumyn L, "Comorbidity in adults with attention-deficit hyperactivity disorder", Can J Psychiatry, 54, pp.673~683 (2009)
  12. Katzman MA, "Re : Is adult attention-deficit hyperactivity disorder being overdiagnosed?", Can J Psychiatry, 61, pp.60~61 (2016)
  13. Ginsberg Y, "Underdiagnosis of attention-deficit", hyperactivity disorder in adult patients : a review of the literature, 2014, pp.16, PCC.13r016~
  14. Harpin VA, "The effect of ADHD on the life of an individual, their family, and community from preschool to adult life", Arch Dis Child, 90(Suppl 1), pp.i2~i7 (2005)
  15. Biederman J, "Attention-deficit", hyperactivity disorder: a life-span perspective, 1998, pp.59(Suppl 7), 4~16
  16. Biederman J, "Do stimulants protect against psychiatric disorders in youth with ADHD? A 10-year follow-up study", Pediatrics, 124, pp.71~78 (2009)
  17. Bobb AJ, "Molecular genetic studies of ADHD: 1991 to 2004", J Med Genet Part B Neuropsychiatr Genet, 141B, pp.551~565 (2004)
  18. 심세훈, "The Relationship between Plasma Erythropoietin Levels and Symptoms of Attention Deficit Hyperactivity Disorder", Clinical Psychopharmacology and Neuroscience, 19(2), pp.334~340 (2021), 대한정신약물학회[DOI]
  19. 이연정, "Associations between the Mismatch-negativity Potential and Symptom Severity in Medication-naïve Children and Adolescents with Symptoms of Attention Deficit", hyperactivity Disorder, 2020, pp.18(2), 249~260[DOI]
  20. Sun Mi Kim, "Effects of Methylphenidate on Somatic Symptoms and Brain Functional Connectivity in Adolescents with Attention Deficit Hyperactivity Disorder: A Pilot Study", Clinical Psychopharmacology and Neuroscience, 20(2), pp.259~270 (2022), 대한정신약물학회[DOI]
  21. Kim L, "A guide for the utilization of Health Insurance Review and Assessment Service national patient samples", Epidemiol Health, 36, pp.e2014008~ (2014)
  22. Xu G, "Twenty-year trends in diagnosed attention-deficit", hyperactivity disorder among US children and adolescents, 1997-2016, 2018, pp.1, e181471~
  23. Zhu Y, "Prevalence of ADHD in publicly insured adults", J Atten Disord, 22, pp.182~190 (2018)
  24. Bachmann CJ, "ADHD in Germany : trends in diagnosis and pharmacotherapy", Dtsch Arztebl Int, 114, pp.141~148 (2017)
  25. Polyzoi M, "Estimated prevalence and incidence of diagnosed ADHD and health care utilization in adults in Sweden-a longitudinal population-based register study", Neuropsychiatr Dis Treat, 14, pp.1149~1161 (2018)
  26. Huang CL, "Gender ratios of administrative prevalence and incidence of attention-deficit", hyperactivity disorder(ADHD)across the lifespan : a nationwide population-based study in Taiwan, 2016, pp.244, 382~387
  27. Gershon J, "A meta-analytic review of gender differences in ADHD", J Atten Disord, 5, pp.143~154 (2002)
  28. Biederman J, "Comorbidity of attention deficit hyperactivity disorder with conduct, depressive, anxiety, and other disorders", Am J Psychiatry, 148, pp.564~577 (1991)
  29. Rutter M, "Isle of Wight revisited : twenty-five years of child psychiatric epidemiology", J Am Acad Child Adolesc Psychiatry, 28, pp.633~653 (1989)
  30. 김경민, "Associations among High Risk for Sleep-disordered Breathing, Related Risk Factors, and Attention Deficit", Hyperactivity Symptoms in Elementary School Children, 2020, pp.18(4), 553~561[DOI]
  31. Heidbreder R, "ADHD symptomatology is best conceptualized as a spectrum : a dimensional versus unitary approach to diagnosis", Atten Defic Hyperact Disord, 7, pp.249~269 (2015)
  32. Kessler RC, "The prevalence and correlates of adult ADHD in the United States : results from the National Comorbidity Survey Replication", Am J Psychiatry, 163, pp.716~723 (2006)
  33. Se-Hoon Shim, "Comparison between Atomoxetine and OROS Methylphenidate as an Adjunctive to SSRIs in Attention-deficit", Hyperactivity Disorder Adults with Comorbid Partially Responsive Major Depressive Disorder: A Head-to-head, 12-week, Randomized, Rater-blinded Clinical Trial, 2022, pp.20(1), 143~153[DOI]
  34. Jensen CM, "Comorbid mental disorders in children and adolescents with attention-deficit", hyperactivity disorder in a large nationwide study, 2015, pp.7, 27~38
  35. Yoshimasu K, "Childhood ADHD is strongly associated with a broad range of psychiatric disorders during adolescence : a population-based birth cohort study", J Child Psychol Psychiatry, 53, pp.1036~1043 (2012)
  36. Silva D, "Child attention deficit hyperactive disorder co morbidities on family stress : effect of medication", Community Ment Health J, 51, pp.347~353 (2015)
  37. Torgersen T, "ADHD in adults : a study of clinical characteristics, impairment and comorbidity", Nord J Psychiatry, 60, pp.38~43 (2006)
  38. Sobanski E, "Psychiatric comorbidity and functional impairment in a clinically referred sample of adults with attention-deficit", hyperactivity disorder(ADHD), 2007, pp.257, 371~377
  39. Reinhold JA, "Adult ADHD : a review of the clinical presentation, challenges, and treatment options", Psychiatr Times, 32, pp.41~ (2015)
  40. Grant BF, "Epidemiology of DSM-5 alcohol use disorder : results from the National Epidemiologic Survey on Alcohol and Related Conditions III", JAMA Psychiatry, 72, pp.757~766 (2015)
  41. Levy E, "Psychotic disorders comorbid with attention-deficit hyperactivity disorder : an important knowledge gap", Can J Psychiatry, 60(3 Suppl 2), pp.S48~S52 (2015)
  42. Dalsgaard S, "Association between Attention-Deficit Hyperactivity Disorder in childhood and schizophrenia later in adulthood", Eur Psychiatry, 29, pp.259~263 (2014)
  43. Owen MJ, "Schizophrenia and the neurodevelopmental continuum : evidence from genomics", World Psychiatry, 16, pp.227~235 (2017)
  44. Ekinci O, "Psychosis associated with switching from risperidone to aripiprazole in an adolescent on methylphenidate treatment", Prog Neuropsychopharmacol Biol Psychiatry, 35, pp.648~649 (2011)
  45. Kooij SJ, "European consensus statement on diagnosis and treatment of adult ADHD : The European Network Adult ADHD", BMC Psychiatry, 10, pp.67~ (2010)
  46. AbikoffH, "Attention-deficit hyperactivity and conduct disorder : comorbidity and implications for treatment", J Consult Clin Psychol, 60, pp.881~892 (1992)

관련 논문AI추천

Prevalence and Comorbidities of Adult Attention-deficit/ hyperactivity Disorder in a Community Sample from Korea박원명, Bo-Hyun Yoon, Hyung Mo Sung, Jeong Seok Seo, Jung Goo Lee, Jung Wan Hong, Se-Hoon Shim, Sung-Yong Park, Young Sup Woo대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2023 · 제21권 제4호국민건강보험 데이터베이스를 이용한 한국의 소아와 성인에서 주의력결핍 과잉행동장애의 진단율 및 약물 사용 추세 연구경장재, 남범우, 서정석, 서정철대한신경정신의학회 · 신경정신의학2021 · 제60권 제4호Medical and Psychiatric Comorbidities in Korean Children and Adolescents with Attention-Deficit/Hyperactivity Disorder박기정, Hyo-Won Kim, Jung Sun Lee대한신경정신의학회 · PSYCHIATRY INVESTIGATION2017 · 제14권 제6호Corrigendum: Prevalence and Comorbidities of Attention Deficit Hyperactivity Disorder Among Adults and Children/Adolescents in KoreaDuk-In Jon, Hyung Mo Sung, Jeong-Cheol Seo, Jeong Seok Seo, Jeongwan Hong, Se-Hoon Shim, Sung‐Yong Park, Won-Myong Bahk, Young Sup Woo대한정신약물학회 · Clinical Psychopharmacology and Neuroscience2022 · 제20권 제2호A Comparison of Comorbidity and Psychological Outcomes in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder정유숙, 홍성도, Inchul Choi, Misun Song, Sunyoung Kim, Yoon Huh대한신경정신의학회 · PSYCHIATRY INVESTIGATION2011 · 제8권 제2호Attention-Deficit/Hyperactivity Disorder Symptom Characteristics in Korean Elementary School Children: Comparison with US PopulationChi-Hyun Choi, Ho-Jang Kwon, Hyun Woo Choi, Ki Chung Paik, Kyoung Min Kim, Myung Ho Lim, Seung-Jin Yoo대한신경정신의학회 · PSYCHIATRY INVESTIGATION2019 · 제16권 제6호

이 간행물의 다른 논문 (19건)