Burden of Ischemic Stroke in Korea: Analysis of Disability-Adjusted Life Years Lost
2
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
Background and Purpose:Disability-adjusted life years (DALY), incorporating both disability and mortality, has been widely employed to measure regional and global burdens of stroke. Thus far, the DALY lost to stroke in a population has been estimated using only the crude population-level data; no previous study has incorporated refined data from stroke registries. The aim of this study was to integrate the stroke registry data and the population-level incidence data to project the nationwide DALY lost to ischemic stroke. Methods:From the data of two large ischemic stroke registries, we derived an average DALY lost due to ischemic stroke for each of the following age groups: <45, 45-54, 55-64, 65-74, 75-84,and ≥85 years. The nationwide ischemic stroke incidence for each age group was extracted from a cardiovascular and cerebrovascular surveillance study that analyzed the 2004 Korean Health Insurance database. Results:The average DALY lost due to ischemic stroke for the age groups <45, 45-54, 55-64,65-74, 75-84, and ≥85 years was 5.07, 4.63, 4.35, 3.88, 2.88, and 1.73, respectively. By multiplying the incidence and the average DALY lost, the nationwide DALY lost was determined to be 9,952 for those <45 years, 24,608 for 45-54 years, 50,682 for 55-64 years, 88,875 for 65-74years, 52,089 for 75-84 years, and 8,192 for ≥85 years, respectively. The projected nationwide DALY lost due to 64,688 ischemic strokes in 2004 was 234,399 (121,482 for men and 113,244 for women), and the DALY lost per 100,000 person-years was 483 (500 for men and 469 for women). Conclusions:Incidence data from a population study and DALY values derived from stroke registries can be integrated to provide a more refined projection of the nationwide burden of ischemic stroke. In Korea, more than 230,000 years of healthy life are being lost annually due to ischemic stroke, and hence prompt action is imperative.
Abstract
Background and Purpose:Disability-adjusted life years (DALY), incorporating both disability and mortality, has been widely employed to measure regional and global burdens of stroke. Thus far, the DALY lost to stroke in a population has been estimated using only the crude population-level data; no previous study has incorporated refined data from stroke registries. The aim of this study was to integrate the stroke registry data and the population-level incidence data to project the nationwide DALY lost to ischemic stroke. Methods:From the data of two large ischemic stroke registries, we derived an average DALY lost due to ischemic stroke for each of the following age groups: <45, 45-54, 55-64, 65-74, 75-84,and ≥85 years. The nationwide ischemic stroke incidence for each age group was extracted from a cardiovascular and cerebrovascular surveillance study that analyzed the 2004 Korean Health Insurance database. Results:The average DALY lost due to ischemic stroke for the age groups <45, 45-54, 55-64,65-74, 75-84, and ≥85 years was 5.07, 4.63, 4.35, 3.88, 2.88, and 1.73, respectively. By multiplying the incidence and the average DALY lost, the nationwide DALY lost was determined to be 9,952 for those <45 years, 24,608 for 45-54 years, 50,682 for 55-64 years, 88,875 for 65-74years, 52,089 for 75-84 years, and 8,192 for ≥85 years, respectively. The projected nationwide DALY lost due to 64,688 ischemic strokes in 2004 was 234,399 (121,482 for men and 113,244 for women), and the DALY lost per 100,000 person-years was 483 (500 for men and 469 for women). Conclusions:Incidence data from a population study and DALY values derived from stroke registries can be integrated to provide a more refined projection of the nationwide burden of ischemic stroke. In Korea, more than 230,000 years of healthy life are being lost annually due to ischemic stroke, and hence prompt action is imperative.
참고문헌 (19)
- Murray CJ, "Rethinking DALYs in: The Global Burden of Disease and Injury Series. Vol 1.", pp.1~98 (1996), Harvard University Press
- "Estimate of DALYs by sex, cause, and WHO region"[URL]
- Johnston SC, "Global variation in stroke burden and mortality: estimates from monitoring, surveillance, and modelling", Lancet Neurol, 8, pp.345~354 (2009)
- O’Donnell MJ, "Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study", Lancet, 376, pp.112~123 (2010)
- "The global burden of cerebrovascular disease"[URL]
- Hong KS, "Quantifying the value of stroke disability outcomes: WHO global burden of disease project disability weights for each level of the modified Rankin Scale", Stroke, 40, pp.3828~3833 (2009)
- Hong KS, "Years of disability-adjusted life gained as a result of thrombolytic therapy for acute ischemic stroke", Stroke, 41, pp.471~477 (2010)
- Hong KS, "Years of Optimum Health Lost Due to Complications After Acute Ischemic Stroke Disability-Adjusted Life-Years Analysis", STROKE, 41, pp.1758~1765, LIPPINCOTT WILLIAMS & WILKINS
- Korean Center for Disease Control, "Construction of National Surveillance System for Cardiovascular & Cerebrovascular Diseases", ~ (2006)
- Hong KS, "Impact of neurological and medical complications on 3-month outcomes in acute ischaemic stroke", Eur J Neurol, 15, pp.1324~1331 (2008)
- "Life Tables for Korea"[URL]
- Eriksson M, "Functional outcome 3 months after stroke predicts long-term survival", Cerebrovasc Dis, 25, pp.423~429 (2008)
- Slot KB, "Oxfordshire Community Stroke Project, the International Stroke Trial (UK); Lothian Stroke Register. Impact of functional status at six months on long term survival in patients with ischaemic stroke: prospective cohort studies", BMJ, 336, pp.376~379 (2008)
- Fox-Rushby JA, "Calculating and presenting disability adjusted life years (DALYs) in cost-effectiveness analysis", Health Policy Plan, 16, pp.326~331 (2001)
- 윤석준, "Estimation of potential health gains from reducing multiple risk factors of stroke in Korea", PUBLIC HEALTH, 121, pp.774~780
- Lee BC, "Korean Stroke Registry. International experience", Am J Prev Med, 31, pp.243~245 (2006)
- 유경호, "한국 뇌졸중 자료은행에 등록된 10,811명의 급성기 허혈성 뇌졸중 환자 분석: 병원기반 다의료기관 전향적 자료등록 연구", 대한신경과학회지, 24(6), pp.535~543 (2006), 대한신경과학회
- Duncan PW, "Measurement of motor recovery after stroke. Outcome assessment and sample size requirements", Stroke, 23, pp.1084~1089 (1992)