The Role of the PI3K Pathway in the Regeneration of the Damaged Brain by Neural Stem Cells after Cerebral Infarction

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참고문헌 (71)

1. Del Zoppo GJ, "Expansion of the time window for treatment of acute ischemic stroke with intravenous tissue plasminogen activator: a science advisory from the American Heart Association", American Stroke Association, 2009, pp.40, 2945~2948[DOI]
2. Zhao H, "Ischemic postconditioning as a novel avenue to protect against brain injury after stroke", J Cereb Blood Flow Metab, 29, pp.873~885 (2009)
3. Chalecka-Franaszek E, "Lithium activates the serine", threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons, 1999, pp.96, 8745~8750
4. Miyawaki T, "The endogenous inhibitor of Akt, CTMP, is critical to ischemia-induced neuronal death", Nat Neurosci, 12, pp.618~626 (2009)
5. Temple S, "Division and differentiation of isolated CNS blast cells in microculture", Nature, 340, pp.471~473 (1989)
6. Doetsch F, "A niche for adult neural stem cells", Curr Opin Genet Dev, 13, pp.543~550 (2003)
7. Yagita Y, "Neurogenesis by progenitor cells in the ischemic adult rat hippocampus", Stroke, 32, pp.1890~1896 (2001)
8. Parent JM, "Rat forebrain neurogenesis and striatal neuron replacement after focal stroke", Ann Neurol, 52, pp.802~813 (2002)
9. Thored P, "Persistent production of neurons from adult brain stem cells during recovery after stroke", Stem Cells, 24, pp.739~747 (2006)
10. Crowder RJ, "Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons", J Neurosci, 18, pp.2933~2943 (1998)
11. Li BS, "Activation of phosphatidylinositol-3 kinase (PI-3K) and extracellular regulated kinases (Erk1", 2) is involved in muscarinic receptor-mediated DNA synthesis in neural progenitor cells, 2001, pp.21, 1569~1579
12. Leevers SJ, "Signalling through phosphoinositide 3-kinases: the lipids take centre stage", Curr Opin Cell Biol, 11, pp.219~225 (1999)
13. Vanhaesebroeck B, "Bilanges B. The emerging mechanisms of isoform-specific PI3K signalling", Nat Rev Mol Cell Biol, 11, pp.329~341 (2010)
14. Knight ZA, "A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling", Cell, 125, pp.733~747 (2006)
15. Auger KR, "PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells", Cell, 57, pp.167~175 (1989)
16. Liu P, "Targeting the phosphoinositide 3-kinase pathway in cancer", Nat Rev Drug Discov, 8, pp.627~644 (2009)
17. Vivanco I, "The phosphatidylinositol 3-Kinase AKT pathway in human cancer", Nat Rev Cancer, 2, pp.489~501 (2002)
18. Mahadevan D, "Phase I pharmacokinetic and pharmacodynamic study of the pan-PI3K", mTORC vascular targeted pro-drug SF1126 in patients with advanced solid tumours and B-cell malignancies, 2012, pp.48, 3319~3327
19. Noh MY, "The early activation of PI3K strongly enhances the resistance of cortical neurons to hypoxic injury via the activation of downstream targets of the PI3K pathway and the normalization of the levels of PARP activity, ATP, and NAD+", Mol Neurobiol, 47, pp.757~769 (2013)
20. Laurino L, "PI3K activation by IGF-1 is essential for the regulation of membrane expansion at the nerve growth cone", J Cell Sci, 118(16), pp.3653~3662 (2005)
21. Cuesto G, "Phosphoinositide-3-kinase activation controls synaptogenesis and spinogenesis in hippocampal neurons", J Neurosci, 31, pp.2721~2733 (2011)
22. Hasegawa Y, "Preservation of tropomyosin-related kinase B (TrkB) signaling by sodium orthovanadate attenuates early brain injury after subarachnoid hemorrhage in rats", Stroke, 42, pp.477~483 (2011)
23. Noshita N, "Copper-zinc superoxide dismutase affects Akt activation after transient focal cerebral ischemia in mice", Stroke, 34, pp.1513~1518 (2003)
24. Kilic E, "The phosphatidylinositol-3 kinase", Akt pathway mediates VEGF’s neuroprotective activity and induces blood brain barrier permeability after focal cerebral ischemia, 2006, pp.20, 1185~1187
25. Bai Y, "An Ang1-Tie2-PI3K axis in neural progenitor cells initiates survival responses against oxygen and glucose deprivation", Neuroscience, 160, pp.371~381 (2009)
26. Xu X, "Neuroprotective effect of humanin on cerebral ischemia", reperfusion injury is mediated by a PI3K, Brain Res, pp.2008, 1227[DOI]
27. Clarke DL, "Generalized potential of adult neural stem cells", Science, 288, pp.1660~1663 (2000)
28. Peltier J, "PI3K", Akt and CREB regulate adult neural hippocampal progenitor proliferation and differentiation, 2007, pp.67, 1348~1361
29. Nguyen N, "Neuroprotection by NGF and BDNF against neurotoxin-exerted apoptotic death in neural stem cells are mediated through Trk receptors, activating PI3-kinase and MAPK pathways", Neurochem Res, 34, pp.942~951 (2009)
30. Park SM, "Transforming growth factor-beta1 regulates the fate of cultured spinal cord-derived neural progenitor cells", Cell Prolif, 41, pp.248~264 (2008)
31. Wu Y, "CXCL12 increases human neural progenitor cell proliferation through Akt-1", FOXO3a signaling pathway, 2009, pp.109, 1157~1167
32. Sato A, "Regulation of neural stem", progenitor cell maintenance by PI3K and mTOR, 2010, pp.470, 115~120
33. Kendall SE, "Neural stem cell targeting of glioma is dependent on phosphoinositide 3-kinase signaling", Stem Cells, 26, pp.1575~1586 (2008)
34. Leong SY, "The Rho kinase pathway regulates mouse adult neural precursor cell migration", Stem Cells, 29, pp.332~343 (2011)
35. Shioda N, "Role of Akt and ERK signaling in the neurogenesis following brain ischemia", Int Rev Neurobiol, 85, pp.375~387 (2009)
36. Wang L, "Neurogenin 1 mediates erythropoietin enhanced differentiation of adult neural progenitor cells", J Cereb Blood Flow Metab, 26, pp.556~564 (2006)
37. Zhang X, "IGF-1 promotes Brn-4 expression and neuronal differentiation of neural stem cells via the PI3K", Akt pathway, 2014, pp.9, e113801~
38. Jin L, "NT3 inhibits FGF2-induced neural progenitor cell proliferation via the PI3K", GSK3 pathway, 2005, pp.93, 1251~1261
39. Chan WS, "Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neural stem", progenitors by ERK1, Front Mol Neurosci, pp.2013, 6[DOI]
40. Gambarotta G, "ErbB4 expression in neural progenitor cells (ST14A) is necessary to mediate neuregulin-1beta1-induced migration", J Biol Chem, 279, pp.48808~48816 (2004)
41. Li S, "Upregulation of CXCR4favoring neural-like cells migration via AKT activation", Neurosci Res, 67, pp.293~299 (2010)
42. Groszer M, "Negative regulation of neural stem", progenitor cell proliferation by the Pten tumor suppressor gene in vivo, 2001, pp.294, 2186~2189
43. Garcia JH, "Neuronal ischemic injury: light microscopy, ultrastructure and biochemistry", Acta Neuropathol, 43, pp.85~95 (1978)
44. Rothman S, "Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death", J Neurosci, 4, pp.1884~1891 (1984)
45. Deshpande JK, "Calcium accumulation and neuronal damage in the rat hippocampus following cerebral ischemia", J Cereb Blood Flow Metab, 7, pp.89~95 (1987)
46. Yuan-Hao Chen, "Analysis of Spatial and Temporal Protein Expression in the Cerebral Cortex after Ischemia-Reperfusion Injury", Journal of Clinical Neurology, 10(2), pp.84~93 (2014), 대한신경과학회[DOI]
47. Endoh M, "Transient global ischemia induces dynamic changes in the expression of bFGF and the FGF receptor", Brain Res Mol Brain Res, 22, pp.76~88 (1994)
48. Zhang RL, "Stroke increases neural stem cells and angiogenesis in the neurogenic niche of the adult mouse", PLoS One, 9, pp.e113972~ (2014)
49. Lindvall O, "Differential regulation of mRNAs for nerve growth factor, brainderived neurotrophic factor, and neurotrophin 3 in the adult rat brain following cerebral ischemia and hypoglycemic coma", Proc Natl Acad Sci U S A, 89, pp.648~652 (1992)
50. Craig CG, "In vivo growth factor expansion of endogenous subependymal neural precursor cell populations in the adult mouse brain", J Neurosci, 16, pp.2649~2658 (1996)
51. Kuhn HG, "Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain", J Neurosci, 17, pp.5820~5829 (1997)
52. Pencea V, "Infusion of brainderived neurotrophic factor into the lateral ventricle of the adult rat leads to new neurons in the parenchyma of the striatum, septum, thalamus, and hypothalamus", J Neurosci, 21, pp.6706~6717 (2001)
53. Nakatomi H, "Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors", Cell, 110, pp.429~441 (2002)
54. Teramoto T, "EGF amplifies the replacement of parvalbumin-expressing striatal interneurons after ischemia", J Clin Invest, 111, pp.1125~1132 (2003)
55. Jin K, "Heparinbinding epidermal growth factor-like growth factor stimulates cell proliferation in cerebral cortical cultures through phosphatidylinositol 3’-kinase and mitogen-activated protein kinase", J Neurosci Res, 81, pp.497~505 (2005)
56. Wang L, "Matrix metalloproteinase 2 (MMP2) and MMP9 secreted by erythropoietin-activated endothelial cells promote neural progenitor cell migration", J Neurosci, 26, pp.5996~6003 (2006)
57. Lee SR, "Involvement of matrix metalloproteinase in neuroblast cell migration from the subventricular zone after stroke", J Neurosci, 26, pp.3491~3495 (2006)
58. Lee JS, "A long-term follow-up study of intravenous autologous mesenchymal stem cell transplantation in patients with ischemic stroke", Stem Cells, 28, pp.1099~1106 (2010), STARTING collaborators
59. Wahane SD, "PI3K-p110-alpha-subtype signalling mediates survival, proliferation and neurogenesis of cortical progenitor cells via activation of mTORC2", J Neurochem, 130, pp.255~267 (2014)
60. Zhang BY, "Akt-independent GSK3 inactivation downstream of PI3K signaling regulates mammalian axon regeneration", Biochem Biophys Res Commun, 443, pp.743~748 (2014)
61. Saijilafu, "PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1", Nat Commun, 4, pp.2690~ (2013)
62. Choi H, "Coenzyme Q10 restores amyloid beta-inhibited proliferation of neural stem cells by activating the PI3K pathway", Stem Cells Dev, 22, pp.2112~2120 (2013)
63. Song J, "The protective effect of melatoninon neural stem cell against LPS-induced inflammation", Biomed Res Int, 2015, pp.854359~ (2015)
64. Sütterlin P, "The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function", Mol Cell Neurosci, 52, pp.20~30 (2013)
65. Dolcet X, "Activation of phosphatidylinositol 3-kinase, but not extracellular-regulated kinases, is necessary to mediate brain-derived neurotrophic factor-induced motoneuron survival", J Neurochem, 73, pp.521~531 (1999)
66. Tsai YW, "Post ischemia intermittent hypoxia induces hippocampal neurogenesis and synaptic alterations and alleviates long-term memory impairment", J Cereb Blood Flow Metab, 33, pp.764~773 (2013)
67. Wang H, "The early stage formation of PI3K-AMPAR GluR2 subunit complex facilitates the long term neuroprotection induced by propofol post-conditioning in rats", PLoS One, 8, pp.e65187~ (2013)
68. Zhu Y, "Vascular endothelial growth factor promotes proliferation of cortical neuron precursors by regulating E2F expression", FASEB J, 17, pp.186~193 (2003)
69. Tu XK, "Repetitive ischemic preconditioning attenuates inflammatory reaction and brain damage after focal cerebral ischemia in rats: involvement of PI3K", Akt and ERK1, J Mol Neurosci, pp.2015, 55[DOI]
70. Qi D, "HO-1 attenuates hippocampal neurons injury via the activation of BDNF-TrkBPI3K", Akt signaling pathway in stroke, 2014, pp.1577, 69~76
71. Liang K, "Formononetin mediates neuroprotection against cerebral ischemia", reperfusion in rats via downregulation of the Bax, Akt signaling pathway, pp.J Neurol Sci, 2014[DOI]

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