Reference Range of Respiratory Muscle Strength and Its Clinical Application in Amyotrophic Lateral Sclerosis: A Single-Center Study
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Background and PurposezzEvaluating respiratory function is important in neuromuscular diseases. Tis study explored the reference ranges of the maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and snif nasal inspiratory pressure (SNIP) in healthy adults, and applied them to amyotrophic lateral sclerosis (ALS) patients. MethodszzMIP, MEP, and SNIP were measured in 67 healthy volunteers aged from 21 to 82 years. Reference ranges were evaluated by multivariate regression analysis using the generalized additive modeling of location, scale, and shape method. Tirty-six ALS patients were reviewed retrospectively, and abnormal values of MIP, MEP, and SNIP were determined according to the reference ranges. ResultszzMIP, MEP, and SNIP were abnormal in 57.1%, 51.4%, and 25.7% of the ALS patients, respectively. MIP and SNIP were signifcantly correlated with the degree of restrictive pattern and respiratory symptoms. Te ALS Functional Rating Scale-Revised score was correlated with SNIP. ConclusionszzTis study has provided the reference range of respiratory muscle strength in healthy adults. Tis range is suitable for evaluating respiratory function in ALS patients.
Abstract
Background and PurposezzEvaluating respiratory function is important in neuromuscular diseases. Tis study explored the reference ranges of the maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP), and snif nasal inspiratory pressure (SNIP) in healthy adults, and applied them to amyotrophic lateral sclerosis (ALS) patients. MethodszzMIP, MEP, and SNIP were measured in 67 healthy volunteers aged from 21 to 82 years. Reference ranges were evaluated by multivariate regression analysis using the generalized additive modeling of location, scale, and shape method. Tirty-six ALS patients were reviewed retrospectively, and abnormal values of MIP, MEP, and SNIP were determined according to the reference ranges. ResultszzMIP, MEP, and SNIP were abnormal in 57.1%, 51.4%, and 25.7% of the ALS patients, respectively. MIP and SNIP were signifcantly correlated with the degree of restrictive pattern and respiratory symptoms. Te ALS Functional Rating Scale-Revised score was correlated with SNIP. ConclusionszzTis study has provided the reference range of respiratory muscle strength in healthy adults. Tis range is suitable for evaluating respiratory function in ALS patients.
참고문헌 (25)
- Gelinas DF, "Pulmonary function screening", Semin Neurol, 23, pp.89~96 (2003)
- Evans JA, "The assessment of maximal respiratory mouth pressures in adults", Respir Care, 54, pp.1348~1359 (2009)
- Morgan RK, "Use of Sniff nasal-inspiratory force to predict survival in amyotrophic lateral sclerosis", Am J Respir Crit Care Med, 171, pp.269~274 (2005)
- 최정근, "한국인의 정상 폐활량 예측치", Tuberculosis and Respiratory Diseases, 58(3), pp.230~242 (2005), 대한결핵및호흡기학회
- Kamide N, "Sniff nasal inspiratory pressure in healthy Japanese subjects: mean values and lower limits of normal", Respiration, 77, pp.58~62 (2009)
- Brooks BR, "El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis", Amyotroph Lateral Scler Other Motor Neuron Disord, 1, pp.293~299 (2000)
- Gordon PH, "ALSFRS-R", Amyotroph Lateral Scler Other Motor Neuron Disord, 5(Suppl 1), pp.90~93 (2004)
- Rigby RA, "Generalized additive models for location, scale and shape", J R Stat Soc: Serie C (Appl Stat), 54, pp.507~554 (2005)
- Cole TJ, "Age- and size-related reference ranges: a case study of spirometry through childhood and adulthood", Stat Med, 28, pp.880~898 (2009)
- Cedarbaum JM, "The ALSFRS-R: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS Study Group (Phase III)", J Neurol Sci, 169, pp.13~21 (1999)
- Harik-Khan RI, "Determinants of maximal inspiratory pressure. The Baltimore Longitudinal Study of Aging", Am J Respir Crit Care Med, 158(5 Pt 1), pp.1459~1464 (1998)
- Pessoa IM, "Predictive equations for respiratory muscle strength according to international and Brazilian guidelines", Braz J Phys Ther, 18, pp.410~418 (2014)
- Huang CH, "Sniff nasal inspiratory pressure does not decrease in elderly subjects", J Phys Ther Sci, 26, pp.1509~1513 (2014)
- Beyerlein A, "Alternative regression models to assess increase in childhood BMI", BMC Med Res Methodol, 8, pp.59~ (2008)
- Black LF, "Maximal respiratory pressures: normal values and relationship to age and sex", Am Rev Respir Dis, 99, pp.696~702 (1969)
- Charfi MR, "Maximal ventilatory pressure through the mouth in adults:normal values and explanatory variables", Rev Mal Respir, 8, pp.367~374 (1991)
- Sclauser Pessoa IM, "Reference values for maximal inspiratory pressure:a systematic review", Can Respir J, 21, pp.43~50 (2014)
- Sachs MC, "Performance of maximum inspiratory pressure tests and maximum inspiratory pressure reference equations for 4 race", ethnic groups, 2009, pp.54, 1321~1328
- Heffernan C, "Management of respiration in MND", ALS patients: an evidence based review, 2006, pp.7, 5~15
- Hardiman O, "Management of respiratory symptoms in ALS", J Neurol, 258, pp.359~365 (2011)
- Gregory SA, "Evaluation and management of respiratory muscle dysfunction in ALS", NeuroRehabilitation, 22, pp.435~443 (2007)
- Schmidt EP, "Pulmonary predictors of survival in amyotrophic lateral sclerosis: use in clinical trial design", Muscle Nerve, 33, pp.127~132 (2006)
- Baumann F, "Use of respiratory function tests to predict survival in amyotrophic lateral sclerosis", Amyotroph Lateral Scler, 11, pp.194~202 (2010)
- Mendoza M, "A comparison of maximal inspiratory pressure and forced vital capacity as potential criteria for initiating non-invasive ventilation in amyotrophic lateral sclerosis", Amyotroph Lateral Scler, 8, pp.106~111 (2007)
- Kaufmann P, "The ALSFRSr predicts survival time in an ALS clinic population", Neurology, 64, pp.38~43 (2005)