Clinical Features of Ocular Toxoplasmosis in Korean Patients
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초록
We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5±13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retinochoroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.
Abstract
We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5±13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retinochoroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.
참고문헌 (20)
- Klaren VN, "Toxoplasmosis, an overview with emphasis on ocular involvement", Ocul Immunol Inflamm, 10, pp.1~26 (2002)
- Holland GN, "Ocular toxoplasmosis: a global reassessment. Part I: epidemiology and course of disease", Am J Ophthalmol, 136, pp.973~988 (2003)
- Bonfioli AA, "Toxoplasmosis", Semin Ophthalmol, 20, pp.129~141 (2005)
- Garweg JG, "Determinants of immunodiagnostic success in human ocular toxoplasmosis", Parasite Immunol, 27, pp.61~68 (2005)
- Tugal-Tutkun I, "Active ocular toxoplasmosis in Turkish patients: a report on 109 cases", Int Ophthalmol, 26, pp.221~228 (2005)
- Dodds EM, "Toxoplasmosis", Curr Opin Ophthalmol, 17, pp.557~561 (2006)
- McCannel CA, "Causes of uveitis in the general practice of ophthalmology", Am J Ophthalmol, 121, pp.35~46 (1996)
- Choi WY, "Foodborne outbreaks of human toxoplasmosis", J Infect Dis, 175, pp.1280~1282 (1997)
- Kim MH, "A toxoplasmic uveitis case of a 60-year-old male in Korea", Korean J Parasitol, 38, pp.29~31 (2000)
- Choi WY, "Toxoplasma antibody titers by indirect latex agglutination test in patients of Kangnam St. Mary’s Hospital and Cheju Medical Center", Korean J Parasitol, 27, pp.171~175 (1989)
- Choi WY, "Diagnosis and epidemiology of toxoplasmosis in Korea", Korean J Parasitol, 28, pp.41~44 (1990)
- Perkins ES, "Ocular toxoplasmosis", Br J Ophthalmol, 57, pp.1~17 (1973)
- Glasner PD, "An unusually high prevalence of ocular toxoplasmosis in southern Brazil", Am J Ophthalmol, 114, pp.136~144 (1992)
- Holland GN, "Ocular toxoplasmosis: new directions for clinical investigation", Ocul Immunol Inflamm, 8, pp.1~7 (2000)
- Atmaca LS, "Clinical features and prognosis in ocular toxoplasmosis", Jpn J Ophthalmol, 48, pp.386~391 (2004)
- Choi WY, "Detection of antibodies in serum and cerebrospinal fluid to Toxoplasma gondii by indirect latex agglutination test and enzyme-linked immunosorbent assay", Korean J Parasitol, 30, pp.83~90 (1992)
- Yang HJ, "Seroprevalence of toxoplasmosis in the residents of Cheju island, Korea", Korean J Parasitol, 38, pp.91~93 (2000)
- 김혜연, "Prevalence of Toxoplasma gondii in Stray Cats of Gyeonggi-do, Korea", The Korean Journal of Parasitology, 46(3), pp.199~201 (2008), 대한기생충학회
- 이상은, "Prevalence of Toxoplasma gondii Infection in Stray and Household Cats in Regions of Seoul, Korea", The Korean Journal of Parasitology, 48(3), pp.267~270 (2010), 대한기생충학회
- Lee SE, "Prevalence of Toxoplasma gondii infection in feral cats in Seoul, Korea", J Parasitol, 97, pp.153~155 (2011)
