Differences in Characteristics and Comorbidity of Cluster Headache According to the Presence of Migraine
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background and Purpose Cluster headache (CH) can present with migrainous symptoms such as nausea, photophobia, and phonophobia. In addition, an overlap between CH and migraine has been reported. This study aimed to determine the differences in the characteristics of CH according to the presence of comorbid migraine. Methods This study was performed using data from a prospective multicenter registry study of CH involving 16 headache clinics. CH and migraine were diagnosed by headache specialists at each hospital based on third edition of the International Classification of Headache Disorders (ICHD-3). We interviewed patients with comorbid migraine to obtain detailed information about migraine. The characteristics and psychological comorbidities of CH were compared between patients with and without comorbid migraine. Results Thirty (15.6%) of 192 patients with CH had comorbid migraine, comprising 18 with migraine without aura, 1 with migraine with aura, 3 with chronic migraine, and 8 with probable migraine. Compared to patients with CH without migraine, patients with CH with comorbid migraine had a shorter duration of CH after the first episode [5.4±7.4 vs. 9.0±8.2 years (mean±standard deviation), p=0.008], a lower frequency of episodic CH (50.0% vs. 73.5%, p= 0.010), and a higher frequency of chronic CH (13.3% vs. 3.7%, p=0.033). Psychiatric comorbidities did not differ between patients with and without comorbid migraine. The headaches experienced by patients could be distinguished based on their trigeminal autonomic symptoms, pulsating character, severity, and pain location. Conclusions Distinct characteristics of CH remained unchanged in patients with comorbid migraine with the exception of an increased frequency of chronic CH. The most appropriate management of CH requires clinicians to check the history of preceding migraine, particularly in cases of chronic CH.
Abstract
Background and Purpose Cluster headache (CH) can present with migrainous symptoms such as nausea, photophobia, and phonophobia. In addition, an overlap between CH and migraine has been reported. This study aimed to determine the differences in the characteristics of CH according to the presence of comorbid migraine. Methods This study was performed using data from a prospective multicenter registry study of CH involving 16 headache clinics. CH and migraine were diagnosed by headache specialists at each hospital based on third edition of the International Classification of Headache Disorders (ICHD-3). We interviewed patients with comorbid migraine to obtain detailed information about migraine. The characteristics and psychological comorbidities of CH were compared between patients with and without comorbid migraine. Results Thirty (15.6%) of 192 patients with CH had comorbid migraine, comprising 18 with migraine without aura, 1 with migraine with aura, 3 with chronic migraine, and 8 with probable migraine. Compared to patients with CH without migraine, patients with CH with comorbid migraine had a shorter duration of CH after the first episode [5.4±7.4 vs. 9.0±8.2 years (mean±standard deviation), p=0.008], a lower frequency of episodic CH (50.0% vs. 73.5%, p= 0.010), and a higher frequency of chronic CH (13.3% vs. 3.7%, p=0.033). Psychiatric comorbidities did not differ between patients with and without comorbid migraine. The headaches experienced by patients could be distinguished based on their trigeminal autonomic symptoms, pulsating character, severity, and pain location. Conclusions Distinct characteristics of CH remained unchanged in patients with comorbid migraine with the exception of an increased frequency of chronic CH. The most appropriate management of CH requires clinicians to check the history of preceding migraine, particularly in cases of chronic CH.
참고문헌 (26)
- "Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition", Cephalalgia, 38, pp.1~211 (2018)
- Srdjan Ljubisavljevic, "Cluster headache: pathophysiology, diagnosis and treatment", Journal of Neurology, 266(5), pp.1059~1066 (2019), Springer Science and Business Media LLC[DOI]
- Burish M, "Cluster headache and other trigeminal autonomic cephalalgias", Continuum (Minneap Minn), 24, pp.1137~1156 (2018)
- Gaul C, "Differences in clinical characteristics and frequency of accompanying migraine features in episodic and chronic cluster headache", Cephalalgia, 32, pp.571~577 (2012)
- Taga A, "Cluster headache with accompanying migraine-like features: a possible clinical phenotype", Headache, 57, pp.290~297 (2017)
- Zidverc-Trajkovic J, "A, Sternic N. Migraine-like accompanying features in patients with cluster headache. How important are they?", Headache, 53, pp.1464~1469 (2013)
- Vollesen AL, "Migraine and cluster headache-the common link", J Headache Pain, 19, pp.89~ (2018)
- Láinez MJ, "Cluster headache and other TACs: pathophysiology and neurostimulation options", Headache, 57, pp.327~335 (2017)
- Vukovic Cvetkovic V, "Neurostimulation for the treatment of chronic migraine and cluster headache", Acta Neurol Scand, 139, pp.4~17 (2019)
- Kudrow L, "Inheritance of cluster headache and its possible link to migraine", Headache, 34, pp.400~407 (1994)
- D’Amico D, "Coexistence of migraine and cluster headache: report of 10 cases and possible pathogenetic implications", Headache, 37, pp.21~25 (1997)
- Steinberg A, "Cluster headache-clinical pattern and a new severity scale in a Swedish cohort", Cephalalgia, 38, pp.1286~1295 (2018)
- Choi YJ, "Impact of cluster headache on employment status and job burden: a prospective cross-sectional multicenter study", J Headache Pain, 19, pp.78~ (2018)
- Headache Classification Committee of the International Headache Society (IHS), "The International Classification of Headache Disorders, 3rd edition (beta version)", Cephalalgia, 33, pp.629~808 (2013)
- 송태진, "Characteristics of Elderly-Onset (≥65 years) Headache Diagnosed Using the International Classification of Headache Disorders, Third Edition Beta Version", Journal of Clinical Neurology, 12(4), pp.419~425 (2016), 대한신경과학회[DOI]
- Sohn JH, "Clinical features of probable cluster headache: a prospective, cross-sectional multicenter study", Front Neurol, 9, pp.908~ (2018)
- Seo JG, "Validation of the Generalized Anxiety Disorder-7(GAD-7) and GAD-2 in patients with migraine", J Headache Pain, 16, pp.97~ (2015)
- Seo JG, "Validation of the Patient Health Questionnaire-9 (PHQ-9) and PHQ-2 in patients with migraine", J Headache Pain, 16, pp.65~ (2015)
- Lee EH, "Korean versions of the Perceived Stress Scale (PSS-14, 10 and 4): psychometric evaluation in patients with chronic disease", Scand J Caring Sci, 29, pp.183~192 (2015)
- Lee YK, "South Korean time trade-off values for EQ-5D health states: modeling with observed values for 101 health states", Value Health, 12, pp.1187~1193 (2009)
- Wei DY, "Cluster headache: epidemiology, pathophysiology, clinical features, and diagnosis", Ann Indian Acad Neurol, 21, pp.S3~S8 (2018)
- Boes CJ, "Wilfred Harris’early description of cluster headache", Cephalalgia, 22, pp.320~326 (2002)
- Mosnaim AD, "Biological correlates of migraine and cluster headaches: an overview of their potential use in diagnosis and treatment", Pragmat Obs Res, 1, pp.25~32 (2010)
- D’Andrea G, "Elevated levels of circulating trace amines in primary headaches", Neurology, 62, pp.1701~1705 (2004)
- Overeem S, "The hypothalamus in episodic brain disorders", Lancet Neurol, 1, pp.437~444 (2002)
- Bahra A, "Diagnostic delays and mis-management in cluster headache", Acta Neurol Scand, 109, pp.175~179 (2004)