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Abrupt Increase in Rate of Imipenem Resistance in Acinetobacter baumannii Complex Strains Isolated from General Hospitals in Korea and Correlation With Carbapenem Administration During 2002–2013

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Dear Editor, Acinetobacter baumannii is a cause of healthcare-associated infections and one of the most important pathogens found in intensive care units (ICUs). The recent dramatic spread of carbapenem-resistant A. baumannii complex (CRAB) in Korea has raised substantial concern in medical practice owing to the lack of adequate therapeutic options [1, 2]. It is well-known that the selective pressure of antibiotics contributes to emergence of new resistant strains [3]. However, there is no sufficient evidence for the association between carbapenem administration and emergence of imipenem-resistant A

Abstract

Dear Editor, Acinetobacter baumannii is a cause of healthcare-associated infections and one of the most important pathogens found in intensive care units (ICUs). The recent dramatic spread of carbapenem-resistant A. baumannii complex (CRAB) in Korea has raised substantial concern in medical practice owing to the lack of adequate therapeutic options [1, 2]. It is well-known that the selective pressure of antibiotics contributes to emergence of new resistant strains [3]. However, there is no sufficient evidence for the association between carbapenem administration and emergence of imipenem-resistant A

참고문헌 (10)

  1. Lee Y, "Recent trends in antimicrobial resistance in intensive care units in Korea", Korean J Nosocomial Infect Control, 19, pp.29~36 (2014)[DOI]
  2. Jasemi S, "Trend of extensively drug-resistant Acinetobacter baumannii and the remaining therapeutic options: a multi-center study in Tehran, Iran over a 3-year period", Lett Appl Microbiol, 63, pp.466~472 (2016)[DOI]
  3. Levy SB, "Antibacterial resistance worldwide: causes, challenges and responses", Nat Med, 10(S12), pp.S122~S129 (2004)[DOI]
  4. Lee J, "Cohort profile: The National Health Insurance Service-National Sample Cohort (NHIS-NSC), South Korea", Int J Epidemiol, 46, pp.e15~ (2017)[DOI]
  5. "Definitions and general considerations" (2016)[URL]
  6. Gurung M, "Emergence and spread of carbapenem-resistant Acinetobacter baumannii sequence type 191 in a Korean hospital", Infect Genet Evol, 19, pp.219~222 (2013)[DOI]
  7. 김용학, "Conditional probability analysis of multidrug resistance in Gram-negative bacilli isolated from tertiary medical institutions in South Korea during 1999–2009", The Journal of Microbiology, 54(1), pp.50~56 (2016), 한국미생물학회[DOI]
  8. Aliramezani A, "Clonal relatedness and biofilm formation of OXA-23-producing carbapenem resistant Acinetobacter baumannii isolates from hospital environment", Microb Pathog, 99, pp.204~208 (2016)[DOI]
  9. Morgenstern H, "Ecologic studies in epidemiology: concepts, principles, and methods", Annu Rev Public Health, 16, pp.61~81 (1995)[DOI]

관련 논문AI추천

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