Process Improvement to Enhance Existing Stroke Team Activity Toward More Timely Thrombolytic Treatment
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background and Purpose Process improvement (PI) is an approach for enhancing the existingquality improvement process by making changes while keeping the existing process. We haveshown that implementation of a stroke code program using a computerized physician order entrysystem is effective in reducing the in-hospital time delay to thrombolysis in acute stroke patients. We investigated whether implementation of this PI could further reduce the time delays by continuous improvement of the existing process. Methods After determining a key indicator [time interval from emergency department (ED) arrival to intravenous (IV) thrombolysis] and conducting data analysis, the target time from ED arrival to IV thrombolysis in acute stroke patients was set at 40 min. The key indicator was monitored continuously at a weekly stroke conference. The possible reasons for the delay were determinedin cases for which IV thrombolysis was not administered within the target time and, where possible, the problems were corrected. The time intervals from ED arrival to the various evaluation stepsand treatment before and after implementation of the PI were compared. Results The median time interval from ED arrival to IV thrombolysis in acute stroke patientswas significantly reduced after implementation of the PI (from 63.5 to 45 min, p=0.001). The variation in the time interval was also reduced. A reduction in the evaluation time intervals wasachieved after the PI [from 23 to 17 min for computed tomography scanning (p=0.003) and from35 to 29 min for complete blood counts (p=0.006)]. Conclusion zPI is effective for continuous improvement of the existing process by reducing thetime delays between ED arrival and IV thrombolysis in acute stroke patients.
Abstract
Background and Purpose Process improvement (PI) is an approach for enhancing the existingquality improvement process by making changes while keeping the existing process. We haveshown that implementation of a stroke code program using a computerized physician order entrysystem is effective in reducing the in-hospital time delay to thrombolysis in acute stroke patients. We investigated whether implementation of this PI could further reduce the time delays by continuous improvement of the existing process. Methods After determining a key indicator [time interval from emergency department (ED) arrival to intravenous (IV) thrombolysis] and conducting data analysis, the target time from ED arrival to IV thrombolysis in acute stroke patients was set at 40 min. The key indicator was monitored continuously at a weekly stroke conference. The possible reasons for the delay were determinedin cases for which IV thrombolysis was not administered within the target time and, where possible, the problems were corrected. The time intervals from ED arrival to the various evaluation stepsand treatment before and after implementation of the PI were compared. Results The median time interval from ED arrival to IV thrombolysis in acute stroke patientswas significantly reduced after implementation of the PI (from 63.5 to 45 min, p=0.001). The variation in the time interval was also reduced. A reduction in the evaluation time intervals wasachieved after the PI [from 23 to 17 min for computed tomography scanning (p=0.003) and from35 to 29 min for complete blood counts (p=0.006)]. Conclusion zPI is effective for continuous improvement of the existing process by reducing thetime delays between ED arrival and IV thrombolysis in acute stroke patients.
참고문헌 (18)
- Hacke W, "Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke", N Engl J Med, 359, pp.1317~1329 (2008)
- Lees KR, "Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials", Lancet, 375, pp.1695~1703 (2010)
- Fonarow GC, "Timeliness of tissue-type plasminogen activator therapy in acute ischemic stroke: patient characteristics, hospital factors, and outcomes associated with door-to-needle times within 60 minutes", Circulation, 123, pp.750~758 (2011)
- Eissa A, "Barriers to the utilization of thrombolysis for acute ischaemic stroke", J Clin Pharm Ther, 37, pp.399~409 (2012)
- California Acute Stroke Pilot Registry (CASPR) Investigators, "Prioritizing interventions to improve rates of thrombolysis for ischemic stroke", Neurology, 64, pp.654~659 (2005)
- Qureshi AI, "Time to hospital arrival, use of thrombolytics, and in-hospital outcomes in ischemic stroke", Neurology, 64, pp.2115~2120 (2005)
- García-Moncó JC, "Analysis of the reasons for exclusion from tPA therapy after early arrival in acute stroke patients", Clin Neurol Neurosurg, 109, pp.50~53 (2007)
- Köhrmann M, "Avoiding in hospital delays and eliminating the three-hour effect in thrombolysis for stroke", Int J Stroke, 6, pp.493~497 (2011)
- Nolte CH, "Improvement of door-to-imaging time in acute stroke patients by implementation of an all-points alarm", J Stroke Cerebrovasc Dis, 22, pp.149~153 (2013)
- Sung SF, "A Parallel Thrombolysis Protocol with Nurse Practitioners As Coordinators Minimized Door-to-Needle Time for Acute Ischemic Stroke", Stroke Res Treat, 2011, pp.198518~ (2011)
- Tai YJ, "Does a ‘code stroke’ rapid access protocol decrease door-to-needle time for thrombolysis?", Intern Med J, 42, pp.1316~1324 (2012)
- Nam HS, "Improved time intervals by implementation of computerized physician order entry-based stroke team approach", Cerebrovasc Dis, 23, pp.289~293 (2007)
- Heo JH, "A computerized in-hospital alert system for thrombolysis in acute stroke", Stroke, 41, pp.1978~1983 (2010)
- Varkey P, "Basics of quality improvement in health care", Mayo Clin Proc, 82, pp.735~739 (2007)
- Strbian D, "Relationship between onset-to-door time and door-to-thrombolysis time: a pooled analysis of 10 dedicated stroke centers", Stroke, 44, pp.2808~2813 (2013)
- Ferrari J, "Stroke thrombolysis: having more time translates into delayed therapy: data from the Austrian Stroke Unit Registry", Stroke, 41, pp.2001~2004 (2010)
- Kwan J, "A systematic review of barriers to delivery of thrombolysis for acute stroke", Age Ageing, 33, pp.116~121 (2004)
- Johnson M, "A review of barriers to thrombolytic therapy: implications for nursing care in the emergency department", J Neurosci Nurs, 42, pp.88~94 (2010)
