A Retrospective 10-Year, Single-Institution Study of Carotid Endarterectomy with a Focus on Elderly Patients
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Background and Purpose Tis study evaluated the outcome following surgery for carotid artery stenosis in a single institution during a 10-year period and the relevance of aging to access to surgery. Methods Between January 2001 and December 2010, 649 carotid endarterectomies (CEAs) were performed in 596 patients for internal carotid artery occlusive disease at our institution; 596 patients received unilateral CEAs and 53 patients received bilateral CEAs. Data regarding patient characteristics, comorbidities, stroke, mortality, restenosis, and other surgical complications were obtained from a review of medical records. Since elderly and high-risk patients comprise a signifcant proportion of the patient group undergoing CEAs, diferences in comorbidity and mortality were evaluated according to age when the patients were divided into three age groups: <70 years, 70–79 years, and ≥80 years. Results Te mean age of the included patients was 67.5 years, and 88% were men. Symptomatic carotid stenosis was observed in 65.7% of patients. Te rate of perioperative stroke and death (within 30 days of the procedure) was 1.84%. Te overall mortality rate was higher among patients in the 70–79 years and >80 years age groups than among those in the <70 years age group, but there was no signifcant diference in stroke-related mortality among these three groups. Conclusions CEA over a 10-year period has yielded acceptable outcomes in terms of stroke and mortality. Terefore, since CEA is a safe and efective strategy, it can be performed in elderly patients with acceptable life expectancy.
Abstract
Background and Purpose Tis study evaluated the outcome following surgery for carotid artery stenosis in a single institution during a 10-year period and the relevance of aging to access to surgery. Methods Between January 2001 and December 2010, 649 carotid endarterectomies (CEAs) were performed in 596 patients for internal carotid artery occlusive disease at our institution; 596 patients received unilateral CEAs and 53 patients received bilateral CEAs. Data regarding patient characteristics, comorbidities, stroke, mortality, restenosis, and other surgical complications were obtained from a review of medical records. Since elderly and high-risk patients comprise a signifcant proportion of the patient group undergoing CEAs, diferences in comorbidity and mortality were evaluated according to age when the patients were divided into three age groups: <70 years, 70–79 years, and ≥80 years. Results Te mean age of the included patients was 67.5 years, and 88% were men. Symptomatic carotid stenosis was observed in 65.7% of patients. Te rate of perioperative stroke and death (within 30 days of the procedure) was 1.84%. Te overall mortality rate was higher among patients in the 70–79 years and >80 years age groups than among those in the <70 years age group, but there was no signifcant diference in stroke-related mortality among these three groups. Conclusions CEA over a 10-year period has yielded acceptable outcomes in terms of stroke and mortality. Terefore, since CEA is a safe and efective strategy, it can be performed in elderly patients with acceptable life expectancy.
참고문헌 (14)
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