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Demographic and Clinical Correlates of Seizure Frequency: Findings from the Managing Epilepsy Well Network Database

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Background and Purpose Epilepsy is a chronic neurological disease that represents a tremendousburden on both patients and society in general. Studies have addressed how demographicvariables, socioeconomic variables, and psychological comorbidity are related to thequality of life (QOL) of people with epilepsy (PWE). However, there has been less focus on howthese factors may differ between patients who exhibit varying degrees of seizure control. Thisstudy utilized data from the Managing Epilepsy Well (MEW) Network of the Centers for DiseaseControl and Prevention with the aim of elucidating differences in demographic variables,depression, and QOL between adult PWE. Methods Demographic variables, depression, and QOL were compared between PWE whoexperience clinically relevant differences in seizure occurrence. Results Gender, ethnicity, race, education, income, and relationship status did not differ significantlybetween the seizure-frequency categories (p>0.05). People with worse seizure controlwere significantly younger (p=0.039), more depressed (as assessed using the Patient HealthQuestionnaire) (p=0.036), and had lower QOL (as determined using the 10-item Quality of Lifein Epilepsy for Adults scale) (p<0.001). Conclusions The present results underscore the importance of early screening, detection, andtreatment of depression, since these factors relate to both seizure occurrence and QOL in PWE.

Abstract

Background and Purpose Epilepsy is a chronic neurological disease that represents a tremendousburden on both patients and society in general. Studies have addressed how demographicvariables, socioeconomic variables, and psychological comorbidity are related to thequality of life (QOL) of people with epilepsy (PWE). However, there has been less focus on howthese factors may differ between patients who exhibit varying degrees of seizure control. Thisstudy utilized data from the Managing Epilepsy Well (MEW) Network of the Centers for DiseaseControl and Prevention with the aim of elucidating differences in demographic variables,depression, and QOL between adult PWE. Methods Demographic variables, depression, and QOL were compared between PWE whoexperience clinically relevant differences in seizure occurrence. Results Gender, ethnicity, race, education, income, and relationship status did not differ significantlybetween the seizure-frequency categories (p>0.05). People with worse seizure controlwere significantly younger (p=0.039), more depressed (as assessed using the Patient HealthQuestionnaire) (p=0.036), and had lower QOL (as determined using the 10-item Quality of Lifein Epilepsy for Adults scale) (p<0.001). Conclusions The present results underscore the importance of early screening, detection, andtreatment of depression, since these factors relate to both seizure occurrence and QOL in PWE.

참고문헌 (40)

  1. Kobau R, "Epilepsy in adults and access to care-United States, 2010", MMWR Morb Mortal Wkly Rep, 61, pp.909~913 (2012)
  2. Yoon D, "Economic impact of epilepsy in the United States", Epilepsia, 50, pp.2186~2191 (2009)[DOI]
  3. Dieleman JL, "US spending on personal health care and public health, 1996-2013", JAMA, 316, pp.2627~2646 (2016)[DOI]
  4. Kleen JK, "Jasper's Basic Mechanisms of the Epilepsies", pp.915~929 (2012), National Center for Biotechnology Information
  5. Lehrner J, "Health-related quality of life (HRQOL), activity of daily living (ADL) and depressive mood disorder in temporal lobe epilepsy patients", Seizure, 8, pp.88~92 (1999)[DOI]
  6. Loring DW, "Determinants of quality of life in epilepsy", Epilepsy Behav, 5, pp.976~980 (2004)[DOI]
  7. Baker GA, "The stigma of epilepsy: a European perspective", Epilepsia, 41, pp.98~104 (2000)[DOI]
  8. Johnson EK, "The relative impact of anxiety, depression, and clinical seizure features on health-related quality of life in epilepsy", Epilepsia, 45, pp.544~550 (2004)[DOI]
  9. Djibuti M, "Influence of clinical, demographic, and socioeconomic variables on quality of life in patients with epilepsy: findings from Georgian study", J Neurol Neurosurg Psychiatry, 74, pp.570~573 (2003)[DOI]
  10. Vickrey BG, "Relationships between seizure severity and health-related quality of life in refractory localization-related epilepsy", Epilepsia, 41, pp.760~764 (2000)[DOI]
  11. Gilliam F, "Psychiatric comorbidity, health, and function in epilepsy", Epilepsy Behav, 4(Suppl 4), pp.S26~S30 (2003)
  12. Azuma H, "Effects of psychosocial functioning, depression, seizure frequency, and employment on quality of life in patients with epilepsy", Epilepsy Behav, 41, pp.18~20 (2014)[DOI]
  13. van Hout B, "Relationship between seizure frequency and costs and quality of life of outpatients with partial epilepsy in France, Germany, and the United Kingdom", Epilepsia, 38, pp.1221~1226 (1997)[DOI]
  14. McLachlan RS, "Health-related quality of life and seizure control in temporal lobe epilepsy", Ann Neurol, 41, pp.482~489 (1997)[DOI]
  15. Lortie A, "The potential for increasing seizure frequency, relapse, and appearance of new seizure types with vigabatrin", Neurology, 43(11 Suppl 5), pp.S24~S27 (1993)
  16. Wiebe S, "A randomized, controlled trial of surgery for temporal-lobe epilepsy", N Engl J Med, 345, pp.311~318 (2001)[DOI]
  17. Sajatovic M, "The managing epilepsy well network: advancing epilepsy self-management", Am J Prev Med, 52(3S3), pp.S241~S245 (2017)[DOI]
  18. Sahoo SS, "Managing information well: toward an ontology-driven informatics platform for data sharing and secondary use in epilepsy self-management research centers", Health Informatics J, 22, pp.548~561 (2016)[DOI]
  19. Caller TA, "A cognitive behavioral intervention (HOBSCOTCH) improves quality of life and attention in epilepsy", Epilepsy Behav, 57, pp.111~117 (2016)
  20. DiIorio C, "Results of a research study evaluating WebEase, an online epilepsy self-management program", Epilepsy Behav, 22, pp.469~474 (2011)[DOI]
  21. Cramer JA, "A brief questionnaire to screen for quality of life in epilepsy: the QOLIE-10", Epilepsia, 37, pp.577~582 (1996)[DOI]
  22. Bautista RE, "Factors associated with utilization of healthcare resources among epilepsy patients", Epilepsy Res, 79, pp.120~129 (2008)[DOI]
  23. Bautista RE, "Factors associated with satisfaction with care among patients with epilepsy", Epilepsy Behav, 11, pp.518~524 (2007)[DOI]
  24. Kroenke K, "The PHQ-9: validity of a brief depression severity measure", J Gen Intern Med, 16, pp.606~613 (2001)[DOI]
  25. Rathore JS, "Validation of the Patient Health Questionnaire-9 (PHQ-9) for depression screening in adults with epilepsy", Epilepsy Behav, 37, pp.215~220 (2014)[DOI]
  26. Seminario NA, "Determination of prevalence of depression in an epilepsy clinic using a brief DSM-IV-based self-report questionnaire", Epilepsy Behav, 15, pp.362~366 (2009)[DOI]
  27. Fiest KM, "Patterns and frequency of the treatment of depression in persons with epilepsy", Epilepsy Behav, 39, pp.59~64 (2014)[DOI]
  28. Shcherbakova N, "Factors associated with seizure recurrence in epilepsy patients treated with antiepileptic monotherapy: a retrospective observational cohort study using US administrative insurance claims", CNS Drugs, 28, pp.1047~1058 (2014)[DOI]
  29. Escoffery C, "Differences in epilepsy self-management behaviors among young and older adults", Austin J Neurol Disord Epilepsy, 3, pp.1015~ (2016)
  30. Jokeit H, "Long term effects of refractory temporal lobe epilepsy on cognitive abilities: a cross sectional study", J Neurol Neurosurg Psychiatry, 67, pp.44~50 (1999)[DOI]
  31. Eatock J, "Managing patient adherence and quality of life in epilepsy", Neuropsychiatr Dis Treat, 3, pp.117~131 (2007)[DOI]
  32. Kerr MP, "International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy", Epilepsia, 52, pp.2133~2138 (2011)[DOI]
  33. LaFrance WC Jr, "Psychiatric comorbidities in epilepsy", Int Rev Neurobiol, 83, pp.347~383 (2008)
  34. Jing Li1, "Systemic Family Therapy of Comorbidity of Anxiety and Depression with Epilepsy in Adolescents", PSYCHIATRY INVESTIGATION, 13(3), pp.305~310 (2016), 대한신경정신의학회[DOI]
  35. DiIorio CK, "The prevention research centers' managing epilepsy well network", Epilepsy Behav, 19, pp.218~224 (2010)[DOI]
  36. Thompson NJ, "Expanding the efficacy of Project UPLIFT: distance delivery of mindfulness-based depression prevention to people with epilepsy", J Consult Clin Psychol, 83, pp.304~313 (2015)[DOI]
  37. Thompson NJ, "Distance delivery of mindfulness-based cognitive therapy for depression: project UPLIFT", Epilepsy Behav, 19, pp.247~254 (2010)[DOI]
  38. Ciechanowski P, "PEARLS depression treatment for individuals with epilepsy: a randomized controlled trial", Epilepsy Behav, 19, pp.225~231 (2010)[DOI]
  39. Chaytor N, "Long-term outcomes from the PEARLS randomized trial for the treatment of depression in patients with epilepsy", Epilepsy Behav, 20, pp.545~549 (2011)[DOI]
  40. Sajatovic M, "Targeted self-management of epilepsy and mental illness for individuals with epilepsy and psychiatric comorbidity", Epilepsy Behav, 64, pp.152~159 (2016)[DOI]

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