Delayed Cerebral Toxoplasmosis in a Kidney Transplant Patient: a Case Report
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초록
Cerebral toxoplasmosis is often life-threatening in an immunocompromised patient due to delayed diagnosis and treatment. Several differential diagnoses could be possible only with preoperative brain images of cerebral toxoplasmosis which show multiple rim-enhancing lesions. Due to the rarity of cerebral toxoplasmosis cases in Korea, the diagnosis and treatment are often delayed. This paper concerns a male patient whose cerebral toxoplasmosis was activated 21 years post kidney transplantation. Brain open biopsy was decided to make an exact diagnosis. Cerebral toxoplasmosis was confirmed by immunohistochemistry and PCR analyses of the tissue samples. Although cerebral toxoplasmosis was under control with medication, the patient did not recover clinically and died due to sepsis and recurrent gastrointestinal bleeding.
Abstract
Cerebral toxoplasmosis is often life-threatening in an immunocompromised patient due to delayed diagnosis and treatment. Several differential diagnoses could be possible only with preoperative brain images of cerebral toxoplasmosis which show multiple rim-enhancing lesions. Due to the rarity of cerebral toxoplasmosis cases in Korea, the diagnosis and treatment are often delayed. This paper concerns a male patient whose cerebral toxoplasmosis was activated 21 years post kidney transplantation. Brain open biopsy was decided to make an exact diagnosis. Cerebral toxoplasmosis was confirmed by immunohistochemistry and PCR analyses of the tissue samples. Although cerebral toxoplasmosis was under control with medication, the patient did not recover clinically and died due to sepsis and recurrent gastrointestinal bleeding.
참고문헌 (9)
- Geita Saadatnia, "A review on human toxoplasmosis", Scandinavian Journal of Infectious Diseases, 44(11), pp.805~814 (2012), Informa UK Limited[DOI]
- Da Cunha S, "Cerebral toxoplasmosis after renal transplantation. Case report and review", Acta Med Port, 7, pp.61~66 (1994)[DOI]
- D. Hill, "Toxoplasma gondii: transmission, diagnosis and prevention", Clinical Microbiology and Infection, 8(10), pp.634~640 (2002), Elsevier BV[DOI]
- Sumeeta Khurana, "Toxoplasmosis in organ transplant recipients: Evaluation, implication, and prevention", Tropical Parasitology, 6(2), pp.123~128 (2016), Medknow[DOI]
- R. Clissold, "Late presentation of toxoplasmosis in renal transplant recipients", Clinical Kidney Journal, 3(5), pp.480~482 (2010), Oxford University Press (OUP)[DOI]
- A. A. E. de Joode, "Tissue is the issue: a solitary cerebral lesion 15 years after kidney transplantation", Clinical Kidney Journal, 4(6), pp.410~412 (2011), Oxford University Press (OUP)[DOI]
- RK Garg, "Multiple ring-enhancing lesions of the brain", Journal of Postgraduate Medicine, 56(4), pp.307~316 (2010), Medknow[DOI]
- K. M. Schwartz, "Pattern of T2 hypointensity associated with ring-enhancing brain lesions can help to differentiate pathology", Neuroradiology, 48(3), pp.143~149 (2006), Springer Science and Business Media LLC[DOI]
- E. Renoult, "Toxoplasmosis in Kidney Transplant Recipients: Report of Six Cases and Review", Clinical Infectious Diseases, 24(4), pp.625~634 (1997), Oxford University Press (OUP)[DOI]