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모유수유아에서의 철결핍 빈혈과 비타민 D 결핍

Iron Deficiency Anemia and Vitamin D Deficiency in Breastfed Infants

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참고문헌

키워드

주제분류소아과학

초록

Purpose: Iron deficiency anemia (IDA) is one of the most common nutritional problems, despite a recent improvement of nutritional status of infants and children. We assessed the risk factors for IDA in infants and vitamin D deficiency and IDA by nutrition analysis. Methods: We analyzed blood tests and evaluated 103 children with IDA and 123 children without IDA, 6-36 months of age, who were cared for in our hospital between March 2006 and July 2010. Nutritional analysis using Canpro was performed among breastfed infants 6∼12 months of age who had been diagnosed with IDA and had detailed diet histories. Results: Breastfed infants accounted for 87.4% and 40.7% of the IDA and comparison groups, respectively. The IDA and comparison groups began weaning food at 6.4±1.8 and 5.9±1.3 months, respectively. In the IDA and comparison groups, 46.4% and 53.5% began to adapt to weaning food within 4 weeks, respectively. The most common reason for hospital care of the IDA group was respiratory symptoms constituting 36.2%. Only 18.6% visited the hospital for palloror anemia. The Canpro analysis, performed on 11 infants with IDA, showed that iron and vitamin D were <40% and 30% of recommended intakes, respectively. Conclusion: Weaning food should be started 4∼6 months of age in breastfed infants. In infants at high risk for IDA and vitamin D deficiency, screening tests should be recommended. The high-risk infants may require iron, vitamin D fortified formula, or oral supplements. (Korean J Pediatr Gastroenterol Nutr 2010; 13: 164∼171)

Abstract

Purpose: Iron deficiency anemia (IDA) is one of the most common nutritional problems, despite a recent improvement of nutritional status of infants and children. We assessed the risk factors for IDA in infants and vitamin D deficiency and IDA by nutrition analysis. Methods: We analyzed blood tests and evaluated 103 children with IDA and 123 children without IDA, 6-36 months of age, who were cared for in our hospital between March 2006 and July 2010. Nutritional analysis using Canpro was performed among breastfed infants 6∼12 months of age who had been diagnosed with IDA and had detailed diet histories. Results: Breastfed infants accounted for 87.4% and 40.7% of the IDA and comparison groups, respectively. The IDA and comparison groups began weaning food at 6.4±1.8 and 5.9±1.3 months, respectively. In the IDA and comparison groups, 46.4% and 53.5% began to adapt to weaning food within 4 weeks, respectively. The most common reason for hospital care of the IDA group was respiratory symptoms constituting 36.2%. Only 18.6% visited the hospital for palloror anemia. The Canpro analysis, performed on 11 infants with IDA, showed that iron and vitamin D were <40% and 30% of recommended intakes, respectively. Conclusion: Weaning food should be started 4∼6 months of age in breastfed infants. In infants at high risk for IDA and vitamin D deficiency, screening tests should be recommended. The high-risk infants may require iron, vitamin D fortified formula, or oral supplements. (Korean J Pediatr Gastroenterol Nutr 2010; 13: 164∼171)

참고문헌 (30)

  1. Brundtland GH, "Reducing risks to health, promoting healthy life", JAMA, 288, pp.1974~ (2002)
  2. Brundtland GH, "Iron deficiency anaemia: assessment, prevention, and control", A guide for programme managers. WHO, 2001, pp.3, 15~22
  3. Yip R, "Declining prevalence of anemia among low-income children in the United States", JAMA, 258, pp.1619~1623 (1987)
  4. Yang YJ, "The prevalence of iron deficiency in preschool children", Korean J Pediatr Hematol Oncol, 5, pp.14~20 (1998)
  5. "National Health Insurance Corporation. Iron deficiency anemia"[URL]
  6. Brotanek JM, "Iron deficiency, prolonged bottle feeding, and racial", ethnic disparities in young children, 2005, pp.159, 1038~1042
  7. 장주희, "철결핍빈혈 영유아의 식이력 조사 및 이유지식의 평가", Korean Journal of Pediatrics, 52(2), pp.159~166 (2009), 대한소아과학회
  8. Ahmed F, "Efficacy of twice-weekly multiple micronutrient supplementation for improving the hemoglobin and micronutrient status of anemic adolescent schoolgirls in Bangladesh", Am J Clin Nutr, 82, pp.829~835 (2005)
  9. Giovannini M, "Double-blind, placebo-controlled trial comparing effects of supplementation with two different combinations of micronutrients delivered as sprinkles on growth, anemia, and iron deficiency in cambodian infants", J Pediatr Gastroenterol Nutr, 42, pp.306~312 (2006)
  10. Henderson A, "Vitamin D and the breastfed infant", J Obstet Gynecol Neonatal Nurs, 34, pp.367~372 (2005)
  11. Dawodu A, "Hypovitaminosis D and vitamin D deficiency in exclusively breast-feeding infants and their mothers in summer: a justification for vitamin D supplementation of breast-feeding infants", J Pediatr, 142, pp.169~173 (2003)
  12. Atiq M, "Vitamin D status of breastfed Pakistani infants", Acta Paediatr, 87, pp.737~740 (1998)
  13. Ho ML, "Randomized study of sunshine exposure and serum 25-OHD in breast-fed infants in Beijing, China", J Pediatr, 107, pp.928~931 (1985)
  14. 박신영, "모유 수유아에서의 무증상적 구루병", Korean Journal of Pediatrics, 50(12), pp.1188~1193 (2007), 대한소아과학회
  15. Dallman PR, "Percentile curves for hemoglobin and red cell volume in infancy and childhood", J Pediatr, 94, pp.26~31 (1979)
  16. "The Korean Nutrition Society. Dietary referance intakes for Koreans"[URL]
  17. Committee on Nutrition, "American Academy of Pediatrics. Pediatric nutrition handbook", American Academy of Pediatrics, ~ (1993)
  18. Hallberg L, "Bioavailable nutrient density: a new concept applied in the interpretation of food iron absorption data", Am J Clin Nutr, 34, pp.2242~2247 (1981)
  19. Lee JS, "Changes on breast milk intake and weight of breast-fed infants during the lactation", The Korean Journal of Nutrition, 30, pp.506~511 (1997)
  20. Dallman PR, "Iron deficiency in infancy and childhood", Am J Clin Nutr, 33, pp.86~118 (1980)
  21. Oski FA, "Effect of iron therapy on behavior performance in nonanemic, iron- deficient infants", Pediatrics, 71, pp.877~880 (1983)
  22. Lozoff B, "Iron deficiency and child development", Food Nutr Bull, 28, pp.560~571 (2007)
  23. Lozoff B, "Long-term developmental outcome of infants with iron deficiency", N Engl J Med, 325, pp.687~694 (1991)
  24. Agaoglu L, "Effects of iron deficiency anemia on cognitive function in children", Arzneimittelforschung, 57, pp.426~430 (2007)
  25. Kajosaari M, "Prophylaxis of atopic disease by six months total solid food elimination. Evaluation of 135 exclusively breast-fed infants of atopic families", Acta Paediatr Scand, 72, pp.411~414 (1983)
  26. Fox AT, "Food allergy as a risk factor for nutritional rickets", Pediatr Allergy Immunol, 15, pp.566~569 (2004)
  27. Schoetzau A, "Effect of exclusive breast-feeding and early solid food avoidance on the incidence of atopic dermatitis in high-risk infants at 1 year of age", Pediatr Allergy Immunol, 13, pp.234~242 (2002)
  28. Frank RG, "and the Committee on Nutrition and Section on Allergy and Immunology. Effects of early nutritional interventions on the development of atopic disease in infants and children: the role of maternal dietary restriction, breastfeeding, timing of introduction of complementary foods, and hydrolyzed formulas", Pediatrics, 121, pp.183~191 (2008)
  29. Wagner CL, "American Academy of Pediatrics, Section on Breastfeeding and Committee on Nutrition. Prevention of rickets and vitamin D deficiency in infants, children, and adolescents", Pediatrics, 122, pp.1142~1152 (2008)
  30. Specker BL, "Effect of race and diet on human milk vitamin D and 25-hydroxyvitamin D", American Journal of Diseases in Children, 139, pp.1134~1137 (1985)

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